Homo sapiens (human): 6196
Help
Entry
6196 CDS
T01001
Symbol
RPS6KA2, HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, p90RSK2, pp90RSK3
Name
(RefSeq) ribosomal protein S6 kinase A2
KO
K04373
ribosomal protein S6 kinase alpha-1/2/3/6 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04010
MAPK signaling pathway
hsa04114
Oocyte meiosis
hsa04150
mTOR signaling pathway
hsa04714
Thermogenesis
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04914
Progesterone-mediated oocyte maturation
hsa04931
Insulin resistance
hsa05135
Yersinia infection
hsa05207
Chemical carcinogenesis - receptor activation
Network
nt06526
MAPK signaling
Element
N01601
ERK-RSK signaling
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
6196 (RPS6KA2)
04150 mTOR signaling pathway
6196 (RPS6KA2)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
6196 (RPS6KA2)
09150 Organismal Systems
09152 Endocrine system
04914 Progesterone-mediated oocyte maturation
6196 (RPS6KA2)
09156 Nervous system
04720 Long-term potentiation
6196 (RPS6KA2)
04722 Neurotrophin signaling pathway
6196 (RPS6KA2)
09159 Environmental adaptation
04714 Thermogenesis
6196 (RPS6KA2)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
6196 (RPS6KA2)
09171 Infectious disease: bacterial
05135 Yersinia infection
6196 (RPS6KA2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
6196 (RPS6KA2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
6196 (RPS6KA2)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
6196 (RPS6KA2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
6196 (RPS6KA2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
6196 (RPS6KA2)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Stress granule specific factors
6196 (RPS6KA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Kdo
Pkinase_fungal
Pkinase_C
APH
YrbL-PhoP_reg
RIO1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
6196
NCBI-ProteinID:
NP_066958
OMIM:
601685
HGNC:
10431
Ensembl:
ENSG00000071242
UniProt:
Q15349
LinkDB
All DBs
Position
6:complement(166409364..166862773)
Genome browser
AA seq
733 aa
AA seq
DB search
MDLSMKKFAVRRFFSVYLRRKSRSKSSSLSRLEEEGVVKEIDISHHVKEGFEKADPSQFE
LLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPF
IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI
IYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSA
DWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCN
RLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDS
PGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVPVHPIVQQLHGNNIHFTDGYEIKED
IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK
FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY
RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL
LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR
LTAMQVLKHPWVVNREYLSPNQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSNLA
QRRGMKRLTSTRL
NT seq
2202 nt
NT seq
+upstream
nt +downstream
nt
atggacctgagcatgaagaagttcgccgtgcgcaggttcttctctgtgtacctgcgcagg
aagtcgcgctccaagagctccagcctgagccggctcgaggaagaaggcgtcgtgaaggag
atagacatcagccatcatgtgaaggagggctttgagaaggcagatccttcccagtttgag
ctgctgaaggttttaggacaaggatcctatggaaaggtgttcctggtgaggaaggtgaag
gggtccgacgctgggcagctctacgccatgaaggtccttaagaaagccaccctaaaagtt
cgggaccgagtgagatcgaagatggagagagacatcttggcagaagtgaatcaccccttc
attgtgaagcttcattatgcctttcagacggaaggaaagctctacctgatcctggacttc
ctgcggggaggggacctcttcacccggctctccaaagaggtcatgttcacggaggaggat
gtcaagttctacctggctgagctggccttggctttagaccatctccacagcctggggatc
atctacagagatctgaagcctgagaacatcctcctggatgaagaggggcacattaagatc
acagatttcggcctgagtaaggaggccattgaccacgacaagagagcgtactccttctgc
gggacgatcgagtacatggcgcccgaggtggtgaaccggcgaggacacacgcagagtgcc
gactggtggtccttcggcgtgctcatgtttgagatgctcacggggtccctgccgttccag
gggaaggacaggaaggagaccatggctctcatcctcaaagccaagctggggatgccgcag
ttcctcagtggggaggcacagagtttgctgcgagctctcttcaaacggaacccctgcaac
cggctgggtgctggcattgacggagtggaggaaattaagcgccatcccttctttgtgacc
atagactggaacacgctgtaccggaaggagatcaagccaccgttcaaaccagcagtgggc
aggcctgaggacaccttccactttgaccccgagttcacagcgcggacgcccacagactct
cctggcgtccccccgagtgcaaacgctcatcacctgtttagaggattcagctttgtggcc
tcaagcctgatccaggagccctcacagcaagatctgcacaaagtcccagttcacccaatc
gtgcagcagttacacgggaacaacatccacttcaccgatggctacgagatcaaggaggac
atcggggtgggctcctactcagtgtgcaagcgatgtgtgcataaagccacagacaccgag
tatgccgtgaagatcattgataagagcaagagagacccctcggaagagattgagatcctc
ctgcggtacggccagcacccgaacatcatcaccctcaaggatgtctatgatgatggcaag
tttgtgtacctggtaatggagctgatgcgtggtggggagctcctggaccgcatcctccgg
cagagatacttctcggagcgcgaagccagtgacgtcctgtgcaccatcaccaagaccatg
gactacctccattcccagggggttgttcatcgagacctgaagccgagtaacatcctgtac
agggatgagtcggggagcccagaatccatccgagtctgcgacttcggctttgccaagcag
ctgcgcgcggggaacgggctgctcatgacaccctgctacacggccaatttcgtggccccg
gaggtcctgaagcgtcaaggctatgatgcggcgtgtgacatctggagtttggggatcctg
ttgtacaccatgctggcaggatttaccccttttgcaaatgggccagacgatacccctgag
gagattctggcgcggatcggcagtgggaagtatgccctttctgggggaaactgggactcg
atatctgacgcagctaaagacgtcgtgtccaagatgctccacgtggaccctcatcagcgc
ctgacggcgatgcaagtgctcaaacacccgtgggtggtcaacagagagtacctgtcccca
aaccagctcagccgacaggacgtgcacctggtgaagggcgcgatggccgccacctacttt
gctctaaacagaacacctcaggccccgcggctggagcccgtgctgtcatccaacctggct
cagcgcagaggcatgaagagactcacgtccacgcggctgtag
DBGET
integrated database retrieval system
