Entry
Symbol
ribH, RIB4
Name
6,7-dimethyl-8-ribityllumazine synthase [EC:
2.5.1.78 ]
Pathway
map01110 Biosynthesis of secondary metabolites
Module
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
M00911 Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD
Reaction
R04457 5-amino-6-(D-ribitylamino)uracil butanedionetransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00740 Riboflavin metabolism
K00794 ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase
Enzymes [BR:ko01000 ]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase
K00794 ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase
BRITE hierarchy
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Genes
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Taxonomy UniProt
Reference
Authors
Mortl S, Fischer M, Richter G, Tack J, Weinkauf S, Bacher A
Title
Biosynthesis of riboflavin. Lumazine synthase of Escherichia coli.
Journal
Reference
Authors
Garcia-Ramirez JJ, Santos MA, Revuelta JL
Title
The Saccharomyces cerevisiae RIB4 gene codes for 6,7-dimethyl-8-ribityllumazine synthase involved in riboflavin biosynthesis. Molecular characterization of the gene and purification of the encoded protein.
Journal
Sequence
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