KEGG ORTHOLOGY: K08887

ORTHOLOGY: K08887

Entry

K08887                      KO

Symbol

ABL2

Name

abelson tyrosine-protein kinase 2 [EC:2.7.10.2]

Pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map05208

Chemical carcinogenesis - reactive oxygen species

map05416

Viral myocarditis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K08887  ABL2; abelson tyrosine-protein kinase 2
   04014 Ras signaling pathway
    K08887  ABL2; abelson tyrosine-protein kinase 2
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K08887  ABL2; abelson tyrosine-protein kinase 2
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K08887  ABL2; abelson tyrosine-protein kinase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K08887  ABL2; abelson tyrosine-protein kinase 2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K08887  ABL2; abelson tyrosine-protein kinase 2
Protein kinases [BR:ko01001]
Non-receptor tyrosine kinases
  ABL family
   K08887  ABL2; abelson tyrosine-protein kinase 2

Other DBs

GO:

0004715

Genes

HSA:

27(ABL2)

PTR:	457552(ABL2)

PPS:	100989642(ABL2)

GGO:	101134626(ABL2)

PON:	100437449(ABL2)

NLE:	100588798(ABL2)

HMH:	116473180(ABL2)

MCC:	717037(ABL2)

MCF:	102119266(ABL2)

MTHB:

126950153

MNI:	105484502(ABL2)

CSAB:

103230516(ABL2)

CATY:

105580801(ABL2)

PANU:

101001946(ABL2)

TGE:	112612953(ABL2)

MLEU:

105530472(ABL2)

RRO:	104672008(ABL2)

RBB:	108541908(ABL2)

TFN:	117076751(ABL2)

PTEH:

111555318(ABL2)

CANG:

105526458

CJC:	100388523(ABL2)

SBQ:	101048073(ABL2)

CIMI:

108301298(ABL2)

CSYR:

103267546(ABL2)

MMUR:

105875497(ABL2)

LCAT:

123635258(ABL2)

PCOQ:

105812142(ABL2)

OGA:	100941536(ABL2)

MMU:	11352(Abl2)

MCAL:

110292303(Abl2)

MPAH:

110322217(Abl2)

RNO:	304883(Abl2)

MCOC:

116101837(Abl2)

ANU:	117716080(Abl2)

MUN:	110563282(Abl2)

CGE:	100772469(Abl2)

MAUA:

101835844(Abl2)

PROB:

127223435(Abl2)

MORG:

121454945(Abl2)

MFOT:

126497347

AAMP:

119827876(Abl2)

NGI:	103728022(Abl2)

HGL:	101704827(Abl2)

CPOC:

100714234(Abl2)

CCAN:

109693442(Abl2)

DORD:

105985112(Abl2)

DSP:	122103748(Abl2)

PLOP:

125358987(Abl2)

NCAR:

124961525

MMMA:

107147340(Abl2)

OCU:

100348328

TUP:	102477086(ABL2)

GVR:	103589503(ABL2)

CFA:	480052(ABL2)

CLUD:

112648535(ABL2)

VVP:	112921838(ABL2)

VLG:	121490712(ABL2)

NPO:	129505901(ABL2)

AML:	100463896(ABL2)

UMR:	103668568(ABL2)

UAH:	113262773(ABL2)

UAR:	123801443(ABL2)

ELK:

111150736

LLV:

125085828

MPUF:

101684271(ABL2)

MNP:	132025479(ABL2)

MLK:	131814575(ABL2)

NVS:	122918641(ABL2)

ORO:	101370104(ABL2)

EJU:	114222891(ABL2)

ZCA:	113932155(ABL2)

MLX:	118014417(ABL2)

NSU:	110574130(ABL2)

LWW:	102743285(ABL2)

FCA:	101080757(ABL2)

PYU:	121011873(ABL2)

PCOO:

112857653(ABL2)

PBG:	122475624(ABL2)

PVIV:

125155745(ABL2)

LRUF:

124510180

PTG:	102951925(ABL2)

PPAD:

109253434(ABL2)

PUC:

125925194

AJU:

106977934

HHV:	120247462(ABL2)

BTA:	511845(ABL2)

BOM:	102266298(ABL2)

BIU:	109570619(ABL2)

BBUB:

102401772(ABL2)

BBIS:

104996021(ABL2)

CHX:	102186140(ABL2)

OAS:	101121110(ABL2)

BTAX:

128061845(ABL2)

ODA:	120880521(ABL2)

CCAD:

122451809(ABL2)

MBEZ:

129551330(ABL2)

SSC:	100627019(ABL2)

CFR:	102517204(ABL2)

CBAI:

105068918(ABL2)

CDK:	105099976(ABL2)

VPC:	102531019(ABL2)

BACU:

103010133(ABL2)

BMUS:

118892037(ABL2)

LVE:	103079814(ABL2)

OOR:	101281891(ABL2)

DLE:	111165720(ABL2)

PCAD:

102992173(ABL2)

PSIU:

116739683(ABL2)

NASI:

112408928(ABL2)

ECB:	100053033(ABL2)

EPZ:	103552276(ABL2)

EAI:	106833930(ABL2)

MYB:	102252160(ABL2)

MYD:	102761256(ABL2)

MMYO:

118673516(ABL2)

MLF:	102427521(ABL2)

PKL:	118721410(ABL2)

EFUS:

103289991(ABL2)

MNA:	107531051(ABL2)

DRO:	112298124(ABL2)

SHON:

118979207(ABL2)

AJM:	119049579(ABL2)

PDIC:

114511873(ABL2)

PHAS:

123818357(ABL2)

MMF:	118637242(ABL2)

PPAM:

129082005(ABL2)

HAI:	109384874(ABL2)

RFQ:	117014852(ABL2)

PALE:

102898166(ABL2)

PGIG:

120617618(ABL2)

PVP:	105292845(ABL2)

RAY:	107509025(ABL2)

MJV:	108393116(ABL2)

TOD:	119241234(ABL2)

SARA:

101553006(ABL2)

SETR:

126013362(ABL2)

LAV:	100676988(ABL2)

TMU:

101351045

ETF:	101639968(ABL2)

DNM:	101437572(ABL2)

MDO:	100016915(ABL2)

GAS:	123247947(ABL2)

SHR:	100934520(ABL2)

AFZ:

127562853

PCW:	110206806(ABL2)

OAA:	100081824(ABL2)

GGA:	395410(ABL2)

PCOC:

116230437(ABL2)

MGP:	100543723(ABL2)

CJO:	107317234(ABL2)

TPAI:

128072363(ABL2)

LMUT:

125692813(ABL2)

NMEL:

110402506(ABL2)

APLA:

101792049(ABL2)

ACYG:

106042494(ABL2)

CATA:

118243610(ABL2)

AFUL:

116491951(ABL2)

TGU:	100223825(ABL2)

LSR:	110479004(ABL2)

SCAN:

103814790(ABL2)

PMOA:

120512186(ABL2)

OTC:	121344229(ABL2)

PRUF:

121359812(ABL2)

GFR:	102041022(ABL2)

FAB:	101815859(ABL2)

OMA:	130256260(ABL2)

PHI:	102102835(ABL2)

PMAJ:

107208205(ABL2)

CCAE:

111932595(ABL2)

CCW:	104693580(ABL2)

CBRC:

103617771(ABL2)

ETL:	114062571(ABL2)

ZAB:	102068637(ABL2)

ACHL:

103808157(ABL2)

SVG:	106852254(ABL2)

MMEA:

130578693(ABL2)

HRT:	120756332(ABL2)

FPG:	101919925(ABL2)

FCH:	102045785(ABL2)

CLV:	102097925(ABL2)

EGZ:	104131470(ABL2)

NNI:	104011337(ABL2)

PCRI:

104029494(ABL2)

PLET:

104619514(ABL2)

PCAO:

104046712(ABL2)

ACUN:

113482760(ABL2)

TALA:

104358502(ABL2)

PADL:

103914132(ABL2)

AFOR:

103896097(ABL2)

ACHC:

115348989(ABL2)

HALD:

104325848(ABL2)

HLE:	104839988(ABL2)

AGEN:

126041486

GCL:

127019004

CCRI:

104160162(ABL2)

CSTI:

104564063(ABL2)

CMAC:

104487172(ABL2)

MUI:	104534078(ABL2)

BREG:

104633596(ABL2)

FGA:	104074107(ABL2)

GSTE:

104258845(ABL2)

MNB:	103774819(ABL2)

OHA:	104334011(ABL2)

NNT:	104406673(ABL2)

SHAB:

115611675(ABL2)

DPUB:

104301526(ABL2)

PGUU:

104468021(ABL2)

ACAR:

104524355(ABL2)

CPEA:

104386100(ABL2)

AVIT:

104271865(ABL2)

CVF:	104293345(ABL2)

RTD:	128913883(ABL2)

CUCA:

104058590(ABL2)

TEO:	104382129(ABL2)

BRHI:

104497918(ABL2)

AAM:	106484954(ABL2)

AROW:

112975049(ABL2)

NPD:	112947703(ABL2)

TGT:	104578872(ABL2)

DNE:	112983699(ABL2)

SCAM:

104142723(ABL2)

ASN:	102368728(ABL2)

AMJ:	102568807(ABL2)

CPOO:

109307168(ABL2)

GGN:	109286972(ABL2)

PSS:	102448736(ABL2)

CMY:	102948203(ABL2)

CCAY:

125641193(ABL2)

DCC:	119859671(ABL2)

CPIC:

101942408(ABL2)

TST:	117881231(ABL2)

CABI:

116834215(ABL2)

MRV:	120369867(ABL2)

ACS:	100558561(abl2)

ASAO:

132774373(ABL2)

PVT:	110077070(ABL2)

SUND:

121928509(ABL2)

PBI:	103062459(ABL2)

PMUR:

107283361(ABL2)

CTIG:

120305398(ABL2)

TSR:	106546416(ABL2)

PGUT:

117661161(ABL2)

APRI:

131196191(ABL2)

PTEX:

113438094(ABL2)

NSS:	113413152(ABL2)

VKO:	123027910(ABL2)

PMUA:

114598566(ABL2)

PRAF:

128415266(ABL2)

ZVI:	118088269(ABL2)

HCG:	128322587(ABL2)

GJA:	107120711(ABL2)

STOW:

125433316(ABL2)

EMC:	129330162(ABL2)

XLA:	373818(abl2.S) 403362(abl2.L)

XTR:	100487790(abl2)

NPR:	108803294(ABL2)

RTEM:

120945834(ABL2)

BBUF:

120978815(ABL2)

BGAR:

122943435(ABL2)

MUO:	115472322(ABL2)

GSH:	117346762(ABL2)

DRE:	570636(abl2)

SRX:	107707589 107758002

SANH:

107657876 107699422

SGH:	107599009 107603207

CCAR:

109059081 109059082

CAUA:

113076349 113091168 113107120

CGIB:

127963504 128018857

PTET:

122350864(abl2)

LROH:

127169383(abl2)

OMC:	131545594(abl2)

PPRM:

120472282(abl2)

RKG:	130091619(abl2)

MAMB:

125279267(abl2)

CIDE:

127517045

MASI:

127414983 127424466

TROS:

130567962(abl2)

TDW:	130440135(abl2)

MANU:

129413650(abl2)

IPU:

108265872

IFU:	128607991(abl2)

PHYP:

113529053(abl2)

SMEO:

124399913(abl2)

TFD:	113655764(abl2)

TVC:	132853406(abl2)

AMEX:

103022317(abl2)

CMAO:

118813702(abl2)

EEE:

113572036

CHAR:

105898316(abl2)

TRU:	101076835(abl2)

TFS:	130528542(abl2)

TNG:	GSTEN00028837G001

LCO:	104929342(abl2)

TBEN:

117487527(abl2)

CGOB:

115006788(abl2)

GACU:

117561315(abl2)

EMAC:

134869723(abl2)

ELY:	117254134(abl2)

EFO:	125895632(abl2)

PLEP:

121966964(abl2)

SLUC:

116055294(abl2)

ECRA:

117950380(abl2)

ESP:	116695807(abl2)

PFLV:

114561212(abl2)

GAT:	120823792(abl2)

PPUG:

119216472(abl2)

AFB:	129094256(abl2)

CLUM:

117729538(abl2)

PSWI:

130193830(abl2)

MSAM:

119900720(abl2)

SCHU:

122877598(abl2)

CUD:	121512046(abl2)

ALAT:

119028076(abl2)

MZE:	101486332(abl2)

ONL:	100707515(abl2)

OAU:	116323142(abl2)

OLA:	101167766(abl2)

OML:	112150521(abl2)

CSAI:

133458402(abl2)

XMA:	102229613(abl2)

XCO:	114150621(abl2)

XHE:	116725324(abl2)

PRET:

103464077(abl2)

PFOR:

103138479(abl2)

PLAI:

106951085(abl2)

PMEI:

106906814(abl2)

GAF:	122838040(abl2)

PPRL:

129373611(abl2)

CVG:	107100934(abl2)

CTUL:

119780867(abl2)

GMU:	124873880(abl2)

NFU:	107393146(abl2)

KMR:	108230803(abl2)

ALIM:

106512185(abl2)

NWH:	119430647(abl2)

AOCE:

111563898(abl2)

MCEP:

125009320(abl2)

CSEM:

103393223(abl2)

POV:

109625699

SSEN:

122781227(abl2)

HHIP:

117759960(abl2)

HSP:	118120942(abl2)

SMAU:

118317946(abl2)

LCF:

108881365

SDU:	111220245(abl2)

SLAL:

111651865(abl2)

XGL:	120790508(abl2)

HCQ:

109532260

SSCV:

125968432

SBIA:

133503498(abl2)

PEE:	133406049(abl2)

PTAO:

133480592(abl2)

BPEC:

110160144(abl2)

MALB:

109967422(abl2)

BSPL:

114853829(abl2)

SJO:	128361467(abl2)

SASA:

106584319 106613905(abl2)

STRU:

115158396 115192490

OTW:	112248210 112251019

OMY:	110521572 110524437

OGO:	123996941 124037779

ONE:	115108433 115145018

OKI:	109897949 109902628

OKE:	118359126(abl2) 118391160

SALP:

111972207 111975275

SNH:	120052522 120054862

CCLU:

121533400 121540239

ELS:	105026367(abl2)

SFM:	108919074 108935246

PKI:	111848965(abl2)

AANG:

118226113(abl2)

LOC:

102686356

PSPA:

121331249(abl2)

ARUT:

117409560(abl2)

PSEX:

120538328(abl2)

LCM:	102352150(ABL2)

CMK:	103179968(abl2)

RTP:	109929176(abl2)

CPLA:

122554479(abl2)

HOC:	132819028(abl2)

LERI:

129701148(abl2)

BBEL:

109464007 109464938 109474030

SRE:	PTSG_08572

» show all

Reference

PMID:20841568

Authors

Colicelli J

Title

ABL tyrosine kinases: evolution of function, regulation, and specificity.

Journal

Sci Signal 3:re6 (2010)
DOI:10.1126/scisignal.3139re6

Sequence

[hsa:27]

LinkDB

DBGET integrated database retrieval system