KEGG   ORTHOLOGY: K12089
Entry
K12089                      KO                                     
Symbol
cag4
Name
cag pathogenicity island protein 4
Pathway
map05120  Epithelial cell signaling in Helicobacter pylori infection
Module
M00564  Helicobacter pylori pathogenicity signature, cagA pathogenicity island
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K12089  cag4; cag pathogenicity island protein 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02044 Secretion system
    K12089  cag4; cag pathogenicity island protein 4
Secretion system [BR:ko02044]
 Type IV secretion system
  Cag pathogenicity island (PAI) protein
   K12089  cag4; cag pathogenicity island protein 4
Other DBs
TC: 3.A.7.12.1
Genes
LCJ: NCTC11976_01777
HPY: HP_0523
HEO: C694_02695
HPJ: jhp_0472(orf9)
HPA: HPAG1_0498
HPS: HPSH_04310
HHP: HPSH112_04435
HHQ: HPSH169_02675
HHR: HPSH417_02490
HPG: HPG27_482(cag4)
HPP: HPP12_0530(cag4)
HPL: HPB8_722(cag4)
HEF: HPF16_0832(cag4)
HPF: HPF30_0801(cag4)
HEQ: HPF32_0502(cag4)
HEX: HPF57_0553(cag4)
HPZ: HPKB_0819
HPD: KHP_0796(cag4)
HEY: MWE_1001
HPYO: HPOK113_0544(cag4)
HPYL: HPOK310_0806(cag4)
HPYR: K747_06675
HPYI: K750_04165
HPYU: K751_03235
HPYM: K749_01315
HEB: U063_0831
HEZ: U064_0834
 » show all
Reference
  Authors
Kutter S, Buhrdorf R, Haas J, Schneider-Brachert W, Haas R, Fischer W
  Title
Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies.
  Journal
J Bacteriol 190:2161-71 (2008)
DOI:10.1128/JB.01341-07
Reference
  Authors
Fischer W, Puls J, Buhrdorf R, Gebert B, Odenbreit S, Haas R
  Title
Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8.
  Journal
Mol Microbiol 42:1337-48 (2001)
DOI:10.1046/j.1365-2958.2001.02714.x
  Sequence
[hpy:HP_0523]
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