| Entry |
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| Symbol |
ddaF
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| Name |
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| Pathway |
| map00998 | Biosynthesis of various antibiotics |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00904 | Dapdiamides biosynthesis, L-2,3-diaminopropanoate => dapdiamide A/B/C |
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| Reaction |
| R10941 | N(beta)-epoxysuccinamoyl-DAP:L-valine ligase (ADP-forming) |
| R10942 | 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-valine ligase (ADP-forming) |
| R10943 | 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-isoleucine ligase (ADP-forming) |
| R10944 | 3-{[(2E)-4-amino-4-oxobut-2-enoyl]amino}-L-alanine:L-leucine ligase (ADP-forming) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00998 Biosynthesis of various antibiotics
K22114 ddaF; dapdiamide synthase
Enzymes [BR:ko01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.47 dapdiamide synthase
K22114 ddaF; dapdiamide synthase
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| Genes |
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| Reference |
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| Authors |
Hollenhorst MA, Clardy J, Walsh CT |
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| Title |
The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics. |
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| Journal |
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| Sequence |
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| LinkDB |
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