Klebsiella pneumoniae blaNDM-1: FH42_22135
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Entry
FH42_22135 CDS
T03440
Symbol
gabD
Name
(GenBank) succinate-semialdehyde dehydrogenase
KO
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00250
Alanine, aspartate and glutamate metabolism
kpb00310
Lysine degradation
kpb00350
Tyrosine metabolism
kpb00650
Butanoate metabolism
kpb00760
Nicotinate and nicotinamide metabolism
kpb01100
Metabolic pathways
kpb01120
Microbial metabolism in diverse environments
Module
kpb_M00956
Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
FH42_22135 (gabD)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
FH42_22135 (gabD)
00310 Lysine degradation
FH42_22135 (gabD)
00350 Tyrosine metabolism
FH42_22135 (gabD)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
FH42_22135 (gabD)
Enzymes [BR:
kpb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
FH42_22135 (gabD)
1.2.1.20 glutarate-semialdehyde dehydrogenase
FH42_22135 (gabD)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
FH42_22135 (gabD)
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GFIT
Motif
Pfam:
Aldedh
TilS
Motif
Other DBs
NCBI-ProteinID:
AIJ43327
UniProt:
A0A086IRV3
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All DBs
Position
complement(4579316..4580764)
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AA seq
482 aa
AA seq
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MQLNDMTLFRQQALIDGQWRDAPNGDVIAVTNPANGEQLGSVPKMGADETREAIEAANRA
LPAWRALTAKERANILRRWFDLMMENQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLLVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELANRAGIPAGVFNVVTGSAGAVGGELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDG
VYDRFAEKLQQAVEKLRIGDGLQDGVTTGPLIDEKAVAKVEEHIADAIAKGAKVVTGGKP
HALGGNFFQPTILVNVPDSAKVAKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIIGINTGIISTEVAPFGGVKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgcaactcaacgatatgacactgtttcgccagcaggcgctgatcgatggccagtggcgc
gatgcgcccaacggcgacgtgattgcggtcaccaacccggccaacggcgagcagctcggc
agcgtgccgaaaatgggcgccgatgaaacccgcgaagcgattgaagccgccaatcgcgcc
ctacccgcctggcgcgccctgaccgccaaagagcgggcgaacattctgcgccgctggttc
gatcttatgatggagaatcaggacgatctcgctcgcctgatgaccctcgagcagggaaaa
ccgttggcggaagccaaaggcgaaatcagctacgccgcctcctttattgagtggttcgcc
gaagaaggtaagcgcatctacggcgacaccattcccggccaccaggccgacaagcgcctg
ctggtgattaagcagcccatcggcgttaccgccgccatcacgccgtggaacttcccggcg
gcgatgatcacccgcaaagcgggcccggcgctggccgccggctgcaccatggtcctgaaa
ccggccagccagacgccgttttccgcgctggcgctggccgaactggcgaatcgcgccggg
atccccgccggagtgttcaacgtggtcaccggctccgccggcgcggtcggcggcgaactg
accagcaacccgctggtgcgcaagctctcctttaccggctctaccgagattggccgccag
ctgatggagcagtgcgcgaaagacatcaaaaaagtctccctggagctgggcggcaacgcg
ccgtttatcgtctttgacgatgccgacctcgataaagccgtcgagggggcgctggcgtcg
aagttccgcaacgccgggcagacctgcgtctgcgccaaccgcctgtacgtccaggacggg
gtgtatgaccgtttcgccgagaagctgcagcaggcggtggaaaaactgcgcattggcgac
ggcctgcaggacggcgtcaccaccggcccgctgatcgacgagaaagccgtggccaaagtt
gaagaacacattgccgatgccatcgccaaaggcgcgaaggtggtcaccggcggcaaaccg
cacgccctgggtggcaacttcttccagccgaccatcctggtcaacgttcccgacagcgcc
aaagtggcgaaagaggagaccttcggcccgctggccccgctgttccgctttaaagatgaa
gccgacgtcattgcccaggccaacgataccgagttcggtctcgccgcctatttctacgcc
cgcgatctgagccgcgtcttccgcgtcggcgaagcgctggagtacggcatcatcggcatc
aataccggcattatctccaccgaagtcgcgccgttcggcggcgttaaggcctccggcctc
ggccgcgaagggtcgaagtacggcatcgaagattacttagaaatcaaatatatgtgcatt
ggcctttaa
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