Klebsiella pneumoniae blaNDM-1: FH42_22535
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Entry
FH42_22535 CDS
T03440
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00470
D-Amino acid metabolism
kpb00550
Peptidoglycan biosynthesis
kpb01100
Metabolic pathways
kpb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
FH42_22535
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FH42_22535
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FH42_22535
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
kpb01011
]
FH42_22535
Enzymes [BR:
kpb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
FH42_22535
Peptidoglycan biosynthesis and degradation proteins [BR:
kpb01011
]
Precursor biosynthesis
Amino acid ligase
FH42_22535
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATPgrasp_ST
GARS_A
RimK
Motif
Other DBs
NCBI-ProteinID:
AIJ43399
UniProt:
W9B565
LinkDB
All DBs
Position
complement(4658284..4659381)
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AA seq
365 aa
AA seq
DB search
MAKMRVGIVFGGKSAEHEVSLQSAKNIVEAIDKSRFDVVLLGIDKQGLWHINDAGNYLLN
AQDPARIALRPSTVTLAQIPGREAQQLINAESGQPLAAIDVIFPIVHGTLGEDGSLQGML
RMANLPFVGSDVLGSAACMDKDVTKRLLRDAGLAVAPFITLTRANRAQFSFADVEAKLGL
PLFVKPANQGSSVGVSKVKNEEQYHQAVALAFEFDHKVVVEQGIKGREIECAVLGNDHPQ
ASTCGEIVLNSEFYAYDTKYIDDQGAQVVVPAAIAPEINDKIRAIAVQAYQTLGCSGMAR
VDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLDYTSLITRLIELALERHAADRAL
KTSMN
NT seq
1098 nt
NT seq
+upstream
nt +downstream
nt
atggcaaagatgagggttgggatcgtttttggcggcaagtcggcggagcatgaagtgtcg
ctgcagtcagcgaagaatatcgtggaagcgattgataaatcgcgcttcgatgtggttctg
ttgggtattgataaacaggggctgtggcacatcaacgacgccggcaactacctgctcaac
gcacaggatcctgcccgcattgccctgcgcccttccacggtgactctggcgcagatcccg
ggccgcgaagcgcagcagctgattaacgccgaaagcggccaaccgctggcggccatcgat
gtgattttcccgatcgtccacggcacgctgggtgaagatggctccctgcaggggatgctg
cgcatggcgaatctgccgttcgtcggctccgatgtgctgggctctgcggcctgtatggac
aaagacgtgaccaaacgtctgctgcgcgacgccgggctcgccgtcgccccgtttatcaca
ctcacccgcgccaaccgcgcgcagttcagctttgccgatgtcgaagcgaagctgggcctg
ccgctgttcgttaagccggctaatcagggatcgtcggttggcgtcagcaaagttaaaaac
gaagagcagtaccatcaggcggtggccctggccttcgaatttgaccataaagtggtggtg
gagcaaggcattaaagggcgggaaattgagtgtgcggtgctgggtaacgaccacccgcag
gccagcacctgcggtgaaatcgtcctcaacagcgagttttacgcctacgacaccaagtat
atcgacgatcagggcgcgcaggtggtagtcccggccgctatcgcccctgagatcaacgac
aaaattcgcgctatcgcggtgcaggcctaccagaccctgggctgcagcggcatggctcgt
gtcgacgtgttcctcaccgccgacaacgaggtggtgatcaacgagatcaacaccctgccg
ggctttaccaacatcagcatgtatccgaagctgtggcaggccagcggtctcgactacacc
agcctgatcacccgcctgattgagctggcgctggagcgccatgccgcggaccgggcgctg
aaaacctccatgaactaa
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