Klebsiella pneumoniae blaNDM-1: FH42_26825
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Entry
FH42_26825 CDS
T03440
Name
(GenBank) dihydrofolate reductase
KO
K18589
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00670
One carbon pool by folate
kpb00790
Folate biosynthesis
kpb01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
FH42_26825
00670 One carbon pool by folate
FH42_26825
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
kpb01504
]
FH42_26825
Enzymes [BR:
kpb01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
FH42_26825
Antimicrobial resistance genes [BR:
kpb01504
]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
FH42_26825
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DHFR_1
AA_kinase
RibD_C
Motif
Other DBs
NCBI-ProteinID:
AIJ44188
UniProt:
B9V4W1
LinkDB
All DBs
Position
plasmid1:complement(75960..76433)
Genome browser
AA seq
157 aa
AA seq
DB search
MKISLMAAKARNGVIGCGSDIPWNAKGEQLLFKAITYNQWLLVGRKTFEAMGALPNRKYA
VVSRSGSVATNDDVVVFPSIEAAMRELKTLTNHVVVSGGGEIYKSLIAHADTLHISTIDS
EPEGNVFFPEIPKEFNVVFEQEFHSNINYRYQIWQRG
NT seq
474 nt
NT seq
+upstream
nt +downstream
nt
gtgaaaatatcactaatggctgcaaaagcaagaaatggggttattggctgcggctcggat
atcccgtggaacgctaaaggtgagcagctgctttttaaagcaataacttacaatcaatgg
ctcttagtcggccgtaaaacatttgaggcaatgggggctctcccaaatagaaagtatgca
gttgtcagccgctcaggatcggtagctactaacgatgatgtggttgtgtttccatctata
gaagcagcaatgagggagctaaagactcttacgaaccatgttgttgtttctggtggtgga
gagatctacaagagtctgatcgcccatgccgacacgctacatatctcgacaatagattcc
gagccagagggcaatgttttctttccggaaatccccaaagagttcaatgtggtgttcgag
caggaatttcattcaaatataaattatcgctatcaaatctggcaaaggggttaa
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