Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_00323
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Entry
KPN_00323 CDS
T00566
Symbol
ddl
Name
(GenBank) D-alanylalanine synthetase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
kpn
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00470
D-Amino acid metabolism
kpn00550
Peptidoglycan biosynthesis
kpn01100
Metabolic pathways
kpn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kpn00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
KPN_00323 (ddl)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KPN_00323 (ddl)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KPN_00323 (ddl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
kpn01011
]
KPN_00323 (ddl)
Enzymes [BR:
kpn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
KPN_00323 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:
kpn01011
]
Precursor biosynthesis
Amino acid ligase
KPN_00323 (ddl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
ATPgrasp_ST
GARS_A
RimK
Motif
Other DBs
NCBI-ProteinID:
ABR75775
UniProt:
A6T5A4
LinkDB
All DBs
Position
complement(363157..364287)
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AA seq
376 aa
AA seq
DB search
MPFDVIWMEVEMAKMRVGIVFGGKSAEHEVSLQSAKNIVEAIDKSRFDVVLLGIDKQGLW
HINDAGNYLLNAQDPARIALRPSTVTLAQIPGREAQQLINAESGQPLAAIDVIFPIVHGT
LGEDGSLQGMLRMANLPFVGSDVLGSAACMDKDVTKRLLRDAGLAVAPFITLTRANRAQF
SFADVEAKLGLPLFVKPANQGSSVGVSKVKNEEQYHQAVALAFEFDHKVVVEQGIKGREI
ECAVLGNDHPQASTCGEIVLNSEFYAYDTKYIDDQGAQVVVPAAIAPEINDKIRAIAVQA
YQTLGCSGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQASGLDYTSLITRLIEL
ALERHAADRALKTSMN
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgccctttgatgttatctggatggaagttgaaatggcaaagatgagggttgggatcgtt
tttggcggcaagtcggcggagcatgaagtgtcgctgcagtcagcgaagaatatcgtggaa
gcgattgataaatcgcgcttcgatgtggttctgttgggtattgataaacaggggctgtgg
catatcaacgacgccggcaactacctgctcaacgcacaggatcctgcccgcattgccctg
cgcccttccacggtgactctggcgcagatcccgggccgcgaagcgcagcagctgattaac
gccgaaagcggccaaccgctggcggccatcgatgtgattttcccgatcgtccacggcacg
ctgggtgaagatggctccctgcaggggatgctgcgcatggcgaatctgccgttcgtcggc
tccgatgtgctgggctctgcggcctgtatggacaaagacgtgaccaaacgtctgctgcgc
gacgccgggctcgccgtcgccccgtttatcacactcacccgcgccaaccgcgcgcagttc
agctttgccgatgtcgaagcgaagcttggcctgccgctgttcgttaagccggctaatcag
ggctcgtcggttggcgtcagcaaagttaaaaacgaagagcagtaccatcaggcggtggcc
ctggccttcgaatttgaccataaagtggtggtggagcaaggcattaaagggcgggaaatt
gagtgtgcggtgctgggtaacgaccacccgcaggccagcacctgcggtgaaatcgtcctc
aacagcgagttttacgcctacgacaccaagtatatcgacgatcagggcgcgcaggtggta
gtcccggccgctatcgcccctgagatcaacgacaaaattcgcgctatcgcggtgcaggcc
taccagaccctgggctgcagcggcatggctcgtgtcgacgtgttcctcaccgccgacaac
gaggtggtgatcaacgagatcaacaccctgccgggctttaccaacatcagcatgtatccg
aagctgtggcaggccagcggtctcgactacaccagcctgatcacccgcctgattgagctg
gcgttggagcgccatgccgcggaccgggcgctgaaaacctccatgaactaa
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