Lactobacillus acidophilus La-14: LA14_0138
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Entry
LA14_0138 CDS
T02647
Name
(GenBank) D-alanine--D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
lad
Lactobacillus acidophilus La-14
Pathway
lad00470
D-Amino acid metabolism
lad00550
Peptidoglycan biosynthesis
lad01100
Metabolic pathways
lad01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lad00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
LA14_0138
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LA14_0138
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LA14_0138
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
lad01011
]
LA14_0138
Enzymes [BR:
lad01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
LA14_0138
Peptidoglycan biosynthesis and degradation proteins [BR:
lad01011
]
Precursor biosynthesis
Amino acid ligase
LA14_0138
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
GARS_A
CPSase_L_D2
ATPgrasp_ST
TTL
Motif
Other DBs
NCBI-ProteinID:
AGK93366
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All DBs
Position
130653..131735
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AA seq
360 aa
AA seq
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MTKKIQVGLIFGGNSSEYEVSIVSGHNIYKAIDKDKFDVHPIWITNEGYFASEEESFKVL
EDPSYQVENPHKVNNISNIIELKNLPEIDVFFPIVHGNLGEDGVLQGLFRLMNKPFVGDD
VLAAAATMDKEFTKILAQRVGVPVADWISIKRFEYDDKNNDKLNYEKVAEKLGHDMFVKP
SNQGSSVGVNHVTNAEEYAAALEEAFKYDDKVLVEETVPGTEVETAVLGNDKPIVAGVGQ
ITNAKGSFYTYENKYDDNSTSKLQIPADLPQDIVDTVRENARKVYEITECSGMARIDSML
TPDGKVVLTEVNALPGFTNISMYPKLFEEAGIPYTELITRLIQAGMDRFDHKKTLLHKHD
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atgactaaaaaaatacaagtcggattaatttttggtggtaactcatcagaatatgaagta
tcaatcgtttcaggtcataatatttataaggcaattgataaagataaatttgatgtacat
ccaatttggattactaatgaaggatactttgcaagtgaagaagaaagcttcaaagtctta
gaagatccttcgtatcaagtggaaaatccacataaggtaaataatatttcaaatattatt
gaattgaagaatttaccagagattgatgtattcttcccaattgttcacggtaatttaggt
gaagatggggtcttacagggattgtttcgcttgatgaacaagccatttgtaggtgacgat
gtcttagctgcagctgcaactatggataaggaatttaccaagattttagctcaaagagtt
ggtgttccagtagctgattggatttcaatcaagcgttttgaatacgatgataagaataat
gataaacttaattatgaaaaagtagctgaaaagcttggtcatgatatgtttgtaaaacca
tctaaccaaggttcatcagttggcgttaaccatgtaactaatgctgaagaatatgctgca
gcattagaagaagcattcaagtacgatgataaggttttagttgaagaaactgttcctggc
accgaagttgaaactgctgtccttggcaacgataagccaattgtagcaggtgttggacaa
atcaccaatgcaaaaggctcattctatacttacgaaaataagtatgatgataattcaact
tctaagttgcaaattcctgcagatttaccacaagatattgttgatactgtcagagaaaat
gctcggaaggtttacgaaattactgaatgtagtggtatggcaagaattgattctatgctt
actccagatggtaaagtagtattaactgaagtgaatgcacttcctggttttactaatatc
agtatgtatcctaagttattcgaagaagctggtattccttacactgaattgattactcgc
ttaatccaagcaggtatggatcgttttgaccacaagaagacattgcttcacaagcatgat
taa
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