KEGG   Loxodonta africana (African savanna elephant): 100677352
Entry
100677352         CDS       T04351                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04010  MAPK signaling pathway
lav04020  Calcium signaling pathway
lav04022  cGMP-PKG signaling pathway
lav04114  Oocyte meiosis
lav04218  Cellular senescence
lav04310  Wnt signaling pathway
lav04360  Axon guidance
lav04370  VEGF signaling pathway
lav04380  Osteoclast differentiation
lav04625  C-type lectin receptor signaling pathway
lav04650  Natural killer cell mediated cytotoxicity
lav04658  Th1 and Th2 cell differentiation
lav04659  Th17 cell differentiation
lav04660  T cell receptor signaling pathway
lav04662  B cell receptor signaling pathway
lav04720  Long-term potentiation
lav04724  Glutamatergic synapse
lav04728  Dopaminergic synapse
lav04921  Oxytocin signaling pathway
lav04922  Glucagon signaling pathway
lav04924  Renin secretion
lav05010  Alzheimer disease
lav05014  Amyotrophic lateral sclerosis
lav05020  Prion disease
lav05022  Pathways of neurodegeneration - multiple diseases
lav05031  Amphetamine addiction
lav05152  Tuberculosis
lav05163  Human cytomegalovirus infection
lav05166  Human T-cell leukemia virus 1 infection
lav05167  Kaposi sarcoma-associated herpesvirus infection
lav05170  Human immunodeficiency virus 1 infection
lav05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lav05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100677352 (PPP3CB)
   04310 Wnt signaling pathway
    100677352 (PPP3CB)
   04370 VEGF signaling pathway
    100677352 (PPP3CB)
   04020 Calcium signaling pathway
    100677352 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    100677352 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100677352 (PPP3CB)
   04218 Cellular senescence
    100677352 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100677352 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    100677352 (PPP3CB)
   04660 T cell receptor signaling pathway
    100677352 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    100677352 (PPP3CB)
   04659 Th17 cell differentiation
    100677352 (PPP3CB)
   04662 B cell receptor signaling pathway
    100677352 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100677352 (PPP3CB)
   04921 Oxytocin signaling pathway
    100677352 (PPP3CB)
   04924 Renin secretion
    100677352 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    100677352 (PPP3CB)
   04728 Dopaminergic synapse
    100677352 (PPP3CB)
   04720 Long-term potentiation
    100677352 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    100677352 (PPP3CB)
   04380 Osteoclast differentiation
    100677352 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100677352 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100677352 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    100677352 (PPP3CB)
   05163 Human cytomegalovirus infection
    100677352 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100677352 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100677352 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100677352 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    100677352 (PPP3CB)
   05020 Prion disease
    100677352 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    100677352 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    100677352 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100677352 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lav01009]
    100677352 (PPP3CB)
Enzymes [BR:lav01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100677352 (PPP3CB)
Protein phosphatases and associated proteins [BR:lav01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100677352 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 100677352
NCBI-ProteinID: XP_023402838
LinkDB
Position
Unknown
AA seq 511 aa
MSVVIYLLLITKISAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLVKEGRVDEEIALRII
NEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYF
SIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSL
PLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQ
EHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITI
FSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEML
VNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLK
GLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMP
PRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtcagtagtgatttatcttttattaattacgaaaatttcagctgtcccgttcccccca
acacatcgcttgacatctgaagaagtatttgatatggatgggatacccagggttgatgtt
ctgaagaaccatttagtaaaagaaggtcgggtagatgaagaaattgcacttagaattatc
aatgagggtgctgccatccttcggagagagaaaaccatgatagaagtagaagctccaatt
acagtgtgtggtgacatccatggccaattttttgatctgatgaaactttttgaagtggga
ggatcacctgctaatacacgatacctttttcttggtgattatgtggacagaggttatttt
agtatagagtgtgtcttatacttatgggtcctgaagattctatacccaagcacattattt
cttctgagaggcaaccatgaatgcagacaccttactgaatattttacctttaagcaggaa
tgtaaaattaaatattcagaaagagtctatgaagcttgtatggaagcattcgatagcctg
cctcttgctgcacttttaaaccaacagtttctttgtgttcatggtggactttcaccagaa
atacacacactggatgatattaggagattagatagattcaaagagccacctgcatttgga
ccaatgtgtgacttgctatggtccgatccctctgaagattttggaaatgaaaaatcacag
gaacattttagtcacaatacagttcgaggatgttcttatttttataactatccagcagtg
tgtgaatttttgcaaaacaataatttgttatcgattattagagctcatgaagctcaagat
gcaggctatagaatgtacagaaaaagtcaaactacagggttcccttcattaataacaatt
ttttcggcacctaattacttagatgtctacaataataaagctgctgtattaaagtatgaa
aataatgtgatgaatattcgacagtttaattgttcaccacatccttactggttgcccaat
tttatggatgtcttcacatggtctttaccatttgttggagaaaaagtgacagaaatgttg
gtaaatgttctcagtatttgctctgatgatgaactaatgaccgaaggtgaagaccagttt
gatgtaggttcagctgcagcacggaaagaaatcataagaaacaaaattcgagcaattggc
aagatggcaagggtcttctctgttctcagggaggagagtgaaagcgtgctgacactcaag
ggcctgactcccacagggatgttgcctagtggagtgttagctggaggacggcagaccctg
caaagtgccacagttgaggcaattgaggctgaaaaagcaatacgaggattctctccacca
catagaatctgcagttttgaagaggcaaagggtttggataggatcaatgagagaatgcca
ccccggaaagatgctgtacagcaagatggtttcaattctctgaacaccgcacatgccact
gagaaccacgggactggcaaccatagtgcccagtga

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