Lemur catta (Ring-tailed lemur): 123635562 Help Entry 123635562         CDS       T08326                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism lcat  Lemur catta (Ring-tailed lemur) Pathway lcat01521   EGFR tyrosine kinase inhibitor resistance lcat04151   PI3K-Akt signaling pathway lcat04217   Necroptosis lcat04380   Osteoclast differentiation lcat04550   Signaling pathways regulating pluripotency of stem cells lcat04620   Toll-like receptor signaling pathway lcat04621   NOD-like receptor signaling pathway lcat04630   JAK-STAT signaling pathway lcat04658   Th1 and Th2 cell differentiation lcat04659   Th17 cell differentiation lcat05140   Leishmaniasis lcat05145   Toxoplasmosis lcat05152   Tuberculosis lcat05160   Hepatitis C lcat05161   Hepatitis B lcat05162   Measles lcat05163   Human cytomegalovirus infection lcat05164   Influenza A lcat05165   Human papillomavirus infection lcat05166   Human T-cell leukemia virus 1 infection lcat05167   Kaposi sarcoma-associated herpesvirus infection lcat05168   Herpes simplex virus 1 infection lcat05169   Epstein-Barr virus infection lcat05171   Coronavirus disease - COVID-19 lcat05200   Pathways in cancer lcat05203   Viral carcinogenesis lcat05212   Pancreatic cancer lcat05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:lcat00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     123635562 (JAK1)    04151 PI3K-Akt signaling pathway     123635562 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     123635562 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     123635562 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     123635562 (JAK1)    04621 NOD-like receptor signaling pathway     123635562 (JAK1)    04658 Th1 and Th2 cell differentiation     123635562 (JAK1)    04659 Th17 cell differentiation     123635562 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     123635562 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     123635562 (JAK1)    05203 Viral carcinogenesis     123635562 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     123635562 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     123635562 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     123635562 (JAK1)    05161 Hepatitis B     123635562 (JAK1)    05160 Hepatitis C     123635562 (JAK1)    05171 Coronavirus disease - COVID-19     123635562 (JAK1)    05164 Influenza A     123635562 (JAK1)    05162 Measles     123635562 (JAK1)    05168 Herpes simplex virus 1 infection     123635562 (JAK1)    05163 Human cytomegalovirus infection     123635562 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     123635562 (JAK1)    05169 Epstein-Barr virus infection     123635562 (JAK1)    05165 Human papillomavirus infection     123635562 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     123635562 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     123635562 (JAK1)    05140 Leishmaniasis     123635562 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     123635562 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:lcat01001]     123635562 (JAK1) Enzymes [BR:lcat01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      123635562 (JAK1) Protein kinases [BR:lcat01001]  Non-receptor tyrosine kinases   JAK family [OT]    123635562 (JAK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  123635562 NCBI-ProteinID:  XP_045403790 LinkDB All DBs Position 3:76783202..76902811 Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVIFYLSDREPLRLSSGEYTAEEL CIRAAQECRISPLCHNLFALYDEKTKLWYAPNRTITADDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN WFNSNDSGNVVYYEVMVTGNLGIQWRQKPNVVPFEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVNINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFERSEVLGGQKQFKNFQIEVRKGRYSLHGSDRSFPSLEDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT LMDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRRSDDLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDTECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSEKKPAAEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctccaagaagaccgaggtgaatctggaggcccccgagccgggggtggaagtgatcttc tatctgtcggacagggagcccctccggctgagcagtggagagtatactgcagaggagctg tgcatcagggctgcgcaggaatgccgtatctctcctctgtgtcacaacctctttgccctg tatgatgagaagaccaagctgtggtatgctccgaatcgcaccatcaccgccgatgacaag atgtcactccggcttcactatcggatgaggttctatttcaccaactggcatgggaccaat gacaatgagcagtcggtgtggcgacattctccaaagaaacagaaaaacggctacgagaag aaaaaggttccagatgcaacccctctccttgacgccagctcgctggaatatctgtttgct cagggacagtatgatttggtgaaatgcctggctcccattcgagaccccaagaccgagcag gatggccatgacattgagaacgagtgtctggggatggccgtcctggccatctcacactat gccatgatgaagaagatgcagctgccggaactgcccaaggatatcagctacaagcgatat attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata aataacgttttcaaggatttcctaaaagaatttaacaacaagaccatttgtgacagcagc gtgtcaacgcatgacctgaaggtgaaatacctggctaccctggaaacgttgacaaaacat tatggtgctgaaatatttgagacctccatgttactgatttcctcagaaaatgagatgaat tggtttaattcaaatgacagtggaaacgtcgtttactatgaagtgatggtgactggaaat cttggaatccagtggaggcagaaaccaaatgttgttccttttgaaaaggaaaaaaataaa ctgaagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttacttccctgaaatcactcacatcgtcataaaggaatct gtggtcaacattaacaagcaggacaacaaaaaaatggaactgaagctctcttcccacgag gaggccttgtcctttgtgtccctggtagacggctacttccggctcacagcagacgcccac cattacctctgcaccgatgtggctcccccgctgatcgtccacaacattcagaacggctgt catggcccaatctgcacagaatatgccatcaataaattgcggcaagaaggaagcgaggag gggatgtacgtgctcaggtggagctgcaccgactttgacaacatcctcatgaccgtcacc tgctttgagaggtctgaggtgctgggcggccagaagcagttcaagaacttccagatcgag gtgcgcaagggccgctacagcctgcacggctcagaccgcagcttccccagcctggaggac ctcatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagaaatctccaacctgctggtggctactaagaaggcc caggagtggcagcccgtctaccccatgagccagctgagttttgatcggatcctcaagaaa gatattatgcagggcgagcaccttgggagaggcacgagaacacacatctactctgggacc ctgatggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttccttggccttctttgaggcagccagcatg atgagacaggtctcccacaagcacatcgtgtacctctacggcgtctgtgtccgagatgtg gagaatatcatggtggaagagtttgtggaaggggggcccctggatctcttcatgcaccgg aggagtgatgatctcaccacaccatggaaattcaaagttgccaaacagctggccagtgcc ctgagctacctggaggataaagacctggtccatggaaacgtgtgcaccaaaaacctcctc ctggcccgtgagggcatcgacactgagtgcggcccattcatcaagctcagcgaccctggc atccccatcactgtgctgtccaggcaagagtgcatagaacgaatcccatggatcgctccc gagtgtgtagaagactccaagaacctgagtgtggctgctgacaaatggagctttggaact acgctctgggaaatctgctacaatggcgagatccccctgaaggacaagacactgatcgag aaagagagattctatgagagccggtgcaggcctgtgacaccatcttgcaaggaactggct gacctcatgacccgctgcatgaattatgaccccaatcagagacccttcttccgagccatc atgagagacatcaataagcttgaagagcagaatccagacatcgtttcagaaaaaaagcca gcagctgaagtggatcccacacattttgaaaagcgcttcctaaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggcgacaataca ggggaacaggtggctgtcaaatctctgaagcctgagagtggaggtaaccacatagctgat ctgaagaaggaaatagagatcttaaggaacctctatcatgagaacatcgtgaagtacaaa ggaatctgcacggaagacggaggaaatggtattaagctcatcatggaatttctgccttcg ggaagtcttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcagctg aagtatgctgttcagatttgtaagggcatggactatttgggttctcggcaatacgtccac cgggacttagcagcaagaaatgtccttgtagagagtgaacaccaagtgaaaattggagac tttggtttaactaaagcaattgaaactgataaggagtattacacagttaaggacgaccgg gacagccctgtgttttggtatgctccagaatgtctcattcagtgtaaattctacatcgcc tccgatgtctggtctttcggagtgactctgcatgaactgctcacttactgtgactcagat tctagtcccatggccttgttcctgaaaatgataggccccactcatggccagatgacagtc acaagacttgtgaatacattaaaagagggaaaacgtttgccatgtccacccaactgtcca gatgaggtttatcaacttatgagaaaatgctgggaattccaaccatccaatcggacaacc tttcagaaccttattgaaggatttgaagcacttttaaaataa

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