KEGG   Limosilactobacillus fermentum CECT 5716: LC40_0318
Entry
LC40_0318         CDS       T01958                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
lfr  Limosilactobacillus fermentum CECT 5716
Pathway
lfr00470  D-Amino acid metabolism
lfr00550  Peptidoglycan biosynthesis
lfr01100  Metabolic pathways
lfr01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:lfr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    LC40_0318
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    LC40_0318
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    LC40_0318
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:lfr01011]
    LC40_0318
Enzymes [BR:lfr01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     LC40_0318
Peptidoglycan biosynthesis and degradation proteins [BR:lfr01011]
 Precursor biosynthesis
  Amino acid ligase
   LC40_0318
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATPgrasp_ST ATP-grasp ATP-grasp_4
Other DBs
NCBI-ProteinID: ADJ40962
LinkDB
Position
530888..532021
AA seq 377 aa
MTEKKLHVALLFGGNSSEHDVSKRSAHNIYDGMDKDKYDVSIFMFTKDGILLDNEASQRI
FDGEPEDQVVQEAYQKMDLDAPLAPIAALSTVKEIDFFYPVIHGNLGEDGTVQGLFRLLK
KPYIGSGIASSAMSFDKDLTKRILNQAGIRNTKYLLVTPQNKDQYSWSRIKEELGDLVFV
KPAKQGSSVGIHKVDTEEEYETAMKDAFTYDYKVLVEAGIKNPREIEISILGNENPIASK
LGGIRVPEGDEFYDYENKFVDASGVVFDLPVIVDDDLAKEITDMALKAYEALGMKGMARI
DFLVDEDGVPYLGEPNTLPGFTNISLYPQMWNISGISYSELIDRLIQLGIEEFEHEGQLR
YDFKALGVEKVGEKRYN
NT seq 1134 nt   +upstreamnt  +downstreamnt
atgacagaaaagaaattacacgttgccctcctgttcggtggaaactcatcagaacacgat
gtttccaagcggtccgcccacaatatttacgatggaatggacaaggacaagtacgatgtg
tcaatcttcatgttcactaaggatggcatcttgctcgacaacgaagcctcccagcggatt
tttgatggcgaaccagaagatcaagtggttcaagaggcctaccaaaagatggacctcgat
gccccattagccccgattgccgccttaagcacggttaaagaaatcgacttcttctacccg
gtgattcacggtaacctgggtgaagacgggaccgtccaaggcctgttccgtctcctcaag
aagccgtacattggctcagggattgcgtcttcggctatgtcctttgataaggacctcacc
aagcggatcctgaaccaagccgggattcggaacacgaagtacctgttggtcaccccgcaa
aacaaggatcaatactcctggtcgcggatcaaagaagagctaggggacctggtcttcgtt
aagccggccaagcaagggtcttccgttgggattcacaaggttgataccgaagaggaatac
gagacggccatgaaggatgccttcacttacgactacaaggttctggttgaagctgggatt
aagaacccgcgggaaatcgaaatctcgattctggggaacgaaaatccgattgcctctaag
ttaggggggattcgggtaccagagggtgacgaattctacgactacgaaaacaagtttgtc
gacgcttccggggtggtctttgacctgccggtaatcgttgacgacgacttagccaaggaa
atcaccgacatggccctgaaggcctacgaagcattagggatgaaggggatggcccggatc
gacttcttggtagacgaagacggcgtcccgtacctgggcgaaccaaacacgctgccaggc
ttcaccaatatctccttgtatccacaaatgtggaatatttcggggattagttactccgaa
ttgattgatcgtctgattcaactcgggattgaagaatttgaacacgaaggccagctccgg
tacgacttcaaggccctgggggtcgaaaaggtcggcgaaaagcgttataactag

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