Lactobacillus helveticus R0052: R0052_00795
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Entry
R0052_00795 CDS
T02217
Symbol
ddl
Name
(GenBank) D-alanine-D-alanine ligase Ddl
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
lhr
Lactobacillus helveticus R0052
Pathway
lhr00470
D-Amino acid metabolism
lhr00550
Peptidoglycan biosynthesis
lhr01100
Metabolic pathways
lhr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lhr00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
R0052_00795 (ddl)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
R0052_00795 (ddl)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
R0052_00795 (ddl)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
lhr01011
]
R0052_00795 (ddl)
Enzymes [BR:
lhr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
R0052_00795 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:
lhr01011
]
Precursor biosynthesis
Amino acid ligase
R0052_00795 (ddl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
GARS_A
CPSase_L_D2
TTL
Motif
Other DBs
NCBI-ProteinID:
AFR21191
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All DBs
Position
138122..139204
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AA seq
360 aa
AA seq
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MTKKTQVGLIFGGNSSEYEVSIVSGRNIYKAIDKEKFDVHPIWITNEGYFANEEESFKVL
EDPSYQVKNPHKVHNISNLIELENLPEIDVFFPIVHGNLGEDGVLQGLFRLMNKPFVGDD
ILAAAVTMDKEFTKILAQRVGVPVADWIAIKRFEYDDKNNDKLDYEKVAEKLGRDMFVKP
SNQGSSVGVSHVTNADEYAAALKEAFKYDDKVLVEKTVPGTEVETAVLGNDKPIVAGVGQ
ITNAKGSFYSYKNKYDDNSTSKLQIPADLPQEIIDTVRRNARKVYEVTECSGMARIDSML
TPGGKVVLTEVNALPGFTNISMYPKLFEEAGVPYTELITRLIEVGMERFDHKKTLLHKHD
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atgactaaaaaaacacaagttggattgatttttggtggtaactcatcagaatatgaagta
tcaattgtttcaggtcgtaatatttataaagcaatcgataaagaaaaatttgatgtacac
ccaatttggattactaatgaaggctactttgcaaatgaagaagaaagtttcaaggtttta
gaagatccttcataccaagtaaagaacccacacaaggttcacaatatttctaatttaatt
gaattagaaaacttaccagaaattgatgtctttttccctattgttcacggtaacttgggt
gaagacggcgttttacaaggtttattccgtttgatgaataagccattcgttggtgatgac
atcttggctgctgccgtaaccatggacaaagaatttaccaagattttagctcaaagagtt
ggcgttcctgttgctgactggatcgcaattaaacgttttgaatacgatgacaaaaataat
gataaacttgattatgaaaaagttgctgaaaaacttggccgtgacatgtttgttaagcca
tctaaccaaggttcatcagttggtgttagccatgtaactaacgctgatgaatatgcagca
gcattaaaagaagcatttaagtacgatgacaaggtattagttgaaaaaactgttcctggt
actgaagtagaaactgccgtacttggtaacgacaagccaattgtagcaggtgtgggacaa
atcaccaatgcaaaaggctcattctacagctataagaacaaatacgatgacaattcaact
tctaagttacaaatccctgcagatttgccacaagaaattattgacaccgtaagaagaaat
gctcgtaaagtttatgaagttaccgaatgtagtggtatggctagaattgactctatgctt
actccaggtggtaaagtagtattgactgaagttaatgctcttccaggctttactaatatc
agtatgtatcctaagttgtttgaagaagcaggtgttccttacactgagttaattactcgt
ttgattgaagtaggaatggaacgttttgaccataagaagactttgcttcataagcacgat
taa
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