Leptospira interrogans serovar Lai 56601: LA_4171
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Entry
LA_4171 CDS
T00098
Symbol
leuB
Name
(GenBank) isocitrate/isopropylmalate dehydrogenase
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
lil
Leptospira interrogans serovar Lai 56601
Pathway
lil00020
Citrate cycle (TCA cycle)
lil00480
Glutathione metabolism
lil01100
Metabolic pathways
lil01110
Biosynthesis of secondary metabolites
lil01120
Microbial metabolism in diverse environments
lil01200
Carbon metabolism
lil01210
2-Oxocarboxylic acid metabolism
lil01230
Biosynthesis of amino acids
Module
lil_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lil_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
lil00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
LA_4171 (leuB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
LA_4171 (leuB)
Enzymes [BR:
lil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
LA_4171 (leuB)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Isocitrate_DH_C_bact
DUF166
Motif
Other DBs
NCBI-ProteinID:
AAN51369
UniProt:
Q8EYP2
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All DBs
Position
I:4147754..4149220
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AA seq
488 aa
AA seq
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MSEKTKIAIAYGDGIGPEIMDATLKILNAAGAKIEPIEIEIGEKVYKEGHSSGIKPEAWD
ILRQTKVFLKAPITTPQGGGYKSLNVTVRTTLGLFANVRPCFSLYPYVETKHPSLDIVII
RENEEDLYTGIEHRQTNDTVQCLKLISHPGSEKIIRYAFEYARAYGRKKVTAMVKDNIMK
QTDGLFHDIFKEVAKEYPELEVNSQIIDIGAANLADRPQNFDVVVTLNLYGDIISDIVAQ
IAGSVGMAGSSNIGEIVSMFEAIHGSAPDIAGKNLANPSGLLNAAVMMLVHIGQPDIAAK
INNAWLLTIEEGIHTGDIFKPGVSRIKVGTKEFSDAVIGNLGHLPGKFKPVSFGKAKKII
IPEYKRNIQKKDLVGVDIFLDWVGKDPNELGNKLKSVSDELMLKIITNRGVKVYPDGQPE
TFLIDHWRCRFVSKNALIKQEDPSYHPISHKQVAELLLKLDLAGFDTIKTENLYYFNGKR
AFSLGQGE
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgtccgaaaaaactaaaatcgcaattgcctacggtgatggaatcggtcctgagattatg
gatgcgactcttaaaattttaaatgctgccggagctaaaattgaaccgattgaaatcgaa
atcggcgaaaaagtttataaggaaggacactcttccggaattaaaccggaagcctgggat
attctgagacaaactaaagtatttctaaaagcacccattacaactcctcaaggaggcggt
tacaaaagtttaaacgttactgtcagaactaccctaggtctatttgcaaacgttagaccc
tgtttttcactgtatccatacgtagaaaccaaacacccttccctagatattgtaatcatc
cgtgaaaatgaagaagatctttatactggaatagaacacagacaaaccaatgacacggtt
caatgccttaaattaatttcccacccaggatcagaaaagatcattcgttacgcattcgaa
tatgcaagagcttacggaagaaaaaaagtaaccgcgatggtaaaggacaatattatgaaa
caaacagacggtttgtttcatgacattttcaaagaagtagccaaagaatatccagaatta
gaagtaaattctcaaatcatagatataggcgcagccaacctagcagacagacctcaaaat
tttgacgtagtagttactttaaatttatatggagatattatttctgatatagtcgctcag
atcgcgggttcagtaggaatggcaggttcttccaacatcggagaaattgtttctatgttc
gaagcaatccacggttctgctccggacatagcaggaaaaaatctggcaaatccatctggc
ttactcaacgccgcagtgatgatgctcgttcacattggacaaccggacatcgctgcaaaa
attaataacgcgtggttattgaccatagaagaaggaattcataccggagatatttttaaa
ccgggagtaagcagaattaaagtgggaaccaaagaattttccgacgcggtaatcggaaat
ttaggtcatcttcctggaaaattcaaaccagtttcttttggaaaggctaagaaaattata
attcctgaatataaaagaaacattcaaaaaaaagatttagtaggagtggatatttttctg
gattgggtaggaaaggatccgaacgaactcggaaataaactcaaatctgtttccgacgaa
ctgatgttaaaaatcatcaccaaccggggagtcaaagtttatcctgacggccaaccggaa
acttttttgatcgatcattggagatgtagatttgtaagcaaaaatgcactgattaaacaa
gaggacccttcctaccatccaatttctcataaacaagtagcagaacttcttttaaagtta
gacttggccggttttgatacaatcaaaacggaaaatctttattactttaacggaaaaaga
gccttttctttagggcaaggagaatga
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