KEGG   Leptonychotes weddellii (Weddell seal): 102739707
Entry
102739707         CDS       T08708                                 
Symbol
RELA
Name
(RefSeq) transcription factor p65
  KO
K04735  transcription factor p65
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww01523  Antifolate resistance
lww04010  MAPK signaling pathway
lww04014  Ras signaling pathway
lww04024  cAMP signaling pathway
lww04062  Chemokine signaling pathway
lww04064  NF-kappa B signaling pathway
lww04066  HIF-1 signaling pathway
lww04071  Sphingolipid signaling pathway
lww04137  Mitophagy - animal
lww04151  PI3K-Akt signaling pathway
lww04210  Apoptosis
lww04211  Longevity regulating pathway
lww04218  Cellular senescence
lww04380  Osteoclast differentiation
lww04613  Neutrophil extracellular trap formation
lww04620  Toll-like receptor signaling pathway
lww04621  NOD-like receptor signaling pathway
lww04622  RIG-I-like receptor signaling pathway
lww04623  Cytosolic DNA-sensing pathway
lww04625  C-type lectin receptor signaling pathway
lww04657  IL-17 signaling pathway
lww04658  Th1 and Th2 cell differentiation
lww04659  Th17 cell differentiation
lww04660  T cell receptor signaling pathway
lww04662  B cell receptor signaling pathway
lww04668  TNF signaling pathway
lww04722  Neurotrophin signaling pathway
lww04917  Prolactin signaling pathway
lww04920  Adipocytokine signaling pathway
lww04926  Relaxin signaling pathway
lww04931  Insulin resistance
lww04932  Non-alcoholic fatty liver disease
lww04933  AGE-RAGE signaling pathway in diabetic complications
lww04936  Alcoholic liver disease
lww05010  Alzheimer disease
lww05022  Pathways of neurodegeneration - multiple diseases
lww05030  Cocaine addiction
lww05132  Salmonella infection
lww05133  Pertussis
lww05134  Legionellosis
lww05135  Yersinia infection
lww05140  Leishmaniasis
lww05142  Chagas disease
lww05145  Toxoplasmosis
lww05146  Amoebiasis
lww05152  Tuberculosis
lww05160  Hepatitis C
lww05161  Hepatitis B
lww05162  Measles
lww05163  Human cytomegalovirus infection
lww05164  Influenza A
lww05165  Human papillomavirus infection
lww05166  Human T-cell leukemia virus 1 infection
lww05167  Kaposi sarcoma-associated herpesvirus infection
lww05168  Herpes simplex virus 1 infection
lww05169  Epstein-Barr virus infection
lww05170  Human immunodeficiency virus 1 infection
lww05171  Coronavirus disease - COVID-19
lww05200  Pathways in cancer
lww05202  Transcriptional misregulation in cancer
lww05203  Viral carcinogenesis
lww05207  Chemical carcinogenesis - receptor activation
lww05208  Chemical carcinogenesis - reactive oxygen species
lww05212  Pancreatic cancer
lww05215  Prostate cancer
lww05220  Chronic myeloid leukemia
lww05221  Acute myeloid leukemia
lww05222  Small cell lung cancer
lww05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lww05321  Inflammatory bowel disease
lww05415  Diabetic cardiomyopathy
lww05417  Lipid and atherosclerosis
lww05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lww00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102739707 (RELA)
   04014 Ras signaling pathway
    102739707 (RELA)
   04064 NF-kappa B signaling pathway
    102739707 (RELA)
   04668 TNF signaling pathway
    102739707 (RELA)
   04066 HIF-1 signaling pathway
    102739707 (RELA)
   04071 Sphingolipid signaling pathway
    102739707 (RELA)
   04024 cAMP signaling pathway
    102739707 (RELA)
   04151 PI3K-Akt signaling pathway
    102739707 (RELA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    102739707 (RELA)
  09143 Cell growth and death
   04210 Apoptosis
    102739707 (RELA)
   04218 Cellular senescence
    102739707 (RELA)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102739707 (RELA)
   04620 Toll-like receptor signaling pathway
    102739707 (RELA)
   04621 NOD-like receptor signaling pathway
    102739707 (RELA)
   04622 RIG-I-like receptor signaling pathway
    102739707 (RELA)
   04623 Cytosolic DNA-sensing pathway
    102739707 (RELA)
   04625 C-type lectin receptor signaling pathway
    102739707 (RELA)
   04660 T cell receptor signaling pathway
    102739707 (RELA)
   04658 Th1 and Th2 cell differentiation
    102739707 (RELA)
   04659 Th17 cell differentiation
    102739707 (RELA)
   04657 IL-17 signaling pathway
    102739707 (RELA)
   04662 B cell receptor signaling pathway
    102739707 (RELA)
   04062 Chemokine signaling pathway
    102739707 (RELA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    102739707 (RELA)
   04917 Prolactin signaling pathway
    102739707 (RELA)
   04926 Relaxin signaling pathway
    102739707 (RELA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102739707 (RELA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102739707 (RELA)
  09149 Aging
   04211 Longevity regulating pathway
    102739707 (RELA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102739707 (RELA)
   05202 Transcriptional misregulation in cancer
    102739707 (RELA)
   05207 Chemical carcinogenesis - receptor activation
    102739707 (RELA)
   05208 Chemical carcinogenesis - reactive oxygen species
    102739707 (RELA)
   05203 Viral carcinogenesis
    102739707 (RELA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102739707 (RELA)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    102739707 (RELA)
   05221 Acute myeloid leukemia
    102739707 (RELA)
   05220 Chronic myeloid leukemia
    102739707 (RELA)
   05215 Prostate cancer
    102739707 (RELA)
   05222 Small cell lung cancer
    102739707 (RELA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102739707 (RELA)
   05170 Human immunodeficiency virus 1 infection
    102739707 (RELA)
   05161 Hepatitis B
    102739707 (RELA)
   05160 Hepatitis C
    102739707 (RELA)
   05171 Coronavirus disease - COVID-19
    102739707 (RELA)
   05164 Influenza A
    102739707 (RELA)
   05162 Measles
    102739707 (RELA)
   05168 Herpes simplex virus 1 infection
    102739707 (RELA)
   05163 Human cytomegalovirus infection
    102739707 (RELA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102739707 (RELA)
   05169 Epstein-Barr virus infection
    102739707 (RELA)
   05165 Human papillomavirus infection
    102739707 (RELA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102739707 (RELA)
   05135 Yersinia infection
    102739707 (RELA)
   05133 Pertussis
    102739707 (RELA)
   05134 Legionellosis
    102739707 (RELA)
   05152 Tuberculosis
    102739707 (RELA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102739707 (RELA)
   05145 Toxoplasmosis
    102739707 (RELA)
   05140 Leishmaniasis
    102739707 (RELA)
   05142 Chagas disease
    102739707 (RELA)
  09163 Immune disease
   05321 Inflammatory bowel disease
    102739707 (RELA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102739707 (RELA)
   05022 Pathways of neurodegeneration - multiple diseases
    102739707 (RELA)
  09165 Substance dependence
   05030 Cocaine addiction
    102739707 (RELA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102739707 (RELA)
   05418 Fluid shear stress and atherosclerosis
    102739707 (RELA)
   05415 Diabetic cardiomyopathy
    102739707 (RELA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102739707 (RELA)
   04932 Non-alcoholic fatty liver disease
    102739707 (RELA)
   04931 Insulin resistance
    102739707 (RELA)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102739707 (RELA)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102739707 (RELA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:lww03000]
    102739707 (RELA)
Transcription factors [BR:lww03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Rel/Ankyrin
    102739707 (RELA)
SSDB
Motif
Pfam: RHD_DNA_bind RHD_dimer
Other DBs
NCBI-GeneID: 102739707
NCBI-ProteinID: XP_030891354
UniProt: A0A7F8RDW8
LinkDB
Position
Unknown
AA seq 571 aa
SVRVLGGIPERRTTIGGKRSPSRDAHRVRRRSRGYGAGHVGPDLFPLIFSSEPAQASGPY
VEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKD
PPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNP
FQVPVEEQRGDYDLNAVRLCFQVTVRDPAGRPLRLSPVLSHPIFDNRAPNTAELKICRVN
RNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADP
SLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFNG
PADPRPPPRRIAVPCRSATSVPKPAPQSYPFTPSLSTINFEEFSPMVFSSGQIPNQTSAL
APAPAPAPAPILAPGLAQAVVPPAPKTTQAGEGTLSEALLQLQFDADEDLGALLGNSADP
AVFTDLASVDNSEFQQLLNQGVSVAPHTAEPMLMEYPEAITRLVTGSQRPPDPAPAPLGA
SGLPNGLLSGDEDFSSIADMDFSALLSQISS
NT seq 1716 nt   +upstreamnt  +downstreamnt
tcggtccgcgtcctgggcggaatccccgaaaggcgcacaacgattggaggaaagcggagt
ccgtcacgtgacgcccaccgggtgcgacgccggtcacgtggctacggcgcgggtcacgtg
ggaccagacctgtttcccctcatcttctcgtctgagcccgcccaggcctccggtccctat
gtggagatcatcgagcagcccaagcagcggggcatgcgcttccgctacaagtgcgagggg
cgctccgccggcagtatcccgggcgagaggagcaccgataccaccaagacccaccccacc
atcaagatcaatggctacaccgggccagggacagttcgcatctccctggtcaccaaggac
ccccctcaccggcctcacccccatgagcttgtgggaaaagactgccgagatggcttctat
gaggctgagctctgcccggaccgctgcatccacagcttccagaacctggggatccagtgt
gtaaagaagcgggacctggagcaggccatcagtcaacgcatccagaccaacaacaatccc
ttccaagttcccgtagaagaacagcgtggagactacgacctgaatgcggtgcggctctgc
ttccaggtgacagtgcgggacccagcaggcaggcccctccgcttgtcacctgtcctctct
catcccatctttgacaaccgtgcccccaacactgccgagctcaagatctgccgagtgaac
cgaaactctgggagctgcctcgggggagatgagatcttcctgctgtgtgacaaggtgcag
aaagaggacattgaagtatatttcacgggaccaggctgggaggcccgaggctccttttct
caagctgatgtccaccgacaagtggccattgtgttccggacacctccctacgcggacccc
agcctgcaggcccccgtgcgtgtctccatgcagctgcggcggccttcagatcgggagctc
agcgagcccatggaattccagtacttgccagacacagatgatcgtcaccggattgaggag
aaacgcaaaaggacatatgagaccttcaagagcatcatgaaaaagagtcctttcaatgga
cccgccgacccccggcctccaccccggcgcattgccgtgccttgccgaagcgcaacttct
gtccccaagccagctccccagtcctatccctttacgccatccctcagcaccatcaacttt
gaggagttctcccccatggtcttttcttcggggcagatcccaaaccagacctctgccttg
gccccagcccctgccccagcccctgccccaatcttagccccaggccttgctcaggctgtg
gtccccccagcccccaagaccacccaggccggggaagggacactctcagaggccctgctg
cagctgcagtttgatgccgacgaagacctgggggccctgctgggcaacagcgctgacccc
gccgtgttcacagacctggcatccgtcgacaactctgagtttcagcagctcctgaaccag
ggtgtatctgtggccccccacacagccgagcccatgctcatggagtaccctgaggcaata
acgcgcctggtgacagggtcccagaggccccctgacccagctcctgctcccctaggggcc
tctgggctccccaacggcctcctctcaggggatgaagacttctcctccattgcagatatg
gacttctcagcccttctgagtcagatcagttcctaa

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