KEGG   Leptonychotes weddellii (Weddell seal): 102739956
Entry
102739956         CDS       T08708                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww03420  Nucleotide excision repair
lww04115  p53 signaling pathway
lww04120  Ubiquitin mediated proteolysis
lww05161  Hepatitis B
lww05169  Epstein-Barr virus infection
lww05200  Pathways in cancer
lww05202  Transcriptional misregulation in cancer
lww05210  Colorectal cancer
lww05212  Pancreatic cancer
lww05213  Endometrial cancer
lww05214  Glioma
lww05216  Thyroid cancer
lww05217  Basal cell carcinoma
lww05218  Melanoma
lww05220  Chronic myeloid leukemia
lww05222  Small cell lung cancer
lww05223  Non-small cell lung cancer
lww05224  Breast cancer
lww05225  Hepatocellular carcinoma
lww05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:lww00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102739956 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    102739956 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    102739956 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102739956 (DDB2)
   05202 Transcriptional misregulation in cancer
    102739956 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102739956 (DDB2)
   05212 Pancreatic cancer
    102739956 (DDB2)
   05225 Hepatocellular carcinoma
    102739956 (DDB2)
   05226 Gastric cancer
    102739956 (DDB2)
   05214 Glioma
    102739956 (DDB2)
   05216 Thyroid cancer
    102739956 (DDB2)
   05220 Chronic myeloid leukemia
    102739956 (DDB2)
   05217 Basal cell carcinoma
    102739956 (DDB2)
   05218 Melanoma
    102739956 (DDB2)
   05213 Endometrial cancer
    102739956 (DDB2)
   05224 Breast cancer
    102739956 (DDB2)
   05222 Small cell lung cancer
    102739956 (DDB2)
   05223 Non-small cell lung cancer
    102739956 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102739956 (DDB2)
   05169 Epstein-Barr virus infection
    102739956 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:lww04121]
    102739956 (DDB2)
   03400 DNA repair and recombination proteins [BR:lww03400]
    102739956 (DDB2)
Ubiquitin system [BR:lww04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     102739956 (DDB2)
DNA repair and recombination proteins [BR:lww03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      102739956 (DDB2)
SSDB
Motif
Pfam: WD40 NBCH_WD40 EF-hand_1
Other DBs
NCBI-GeneID: 102739956
NCBI-ProteinID: XP_006730245
UniProt: A0A2U3XFI3
LinkDB
Position
Unknown
AA seq 426 aa
MAPRKRPETQKTLEVAVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPSCSIVRALHRHKLGKAVRPSLQQGLQQAFLHSLASYRIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGTT
RLQDFKGNTLRVFTSSGTCNFWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDGA
QLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKATWHPRYNLVVVGRYPDPNF
KSCTPHELRTIDVFDGNSGKMMYQLYDPESSGIISLNEFNPMGDTLASVMGYHILIWSQE
EAGMRT
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcctaggaaacgcccagaaacccagaagaccctcgaggtggcagtacgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcgggcttggctagcctg
caggtcccgccatcatgcagcatcgtcagggccctccaccgccataagctgggcaaggct
gtccggccatcactacagcagggtctccagcaggcctttctgcactctctggcttcttac
cggatattccaaaaggctgccccctttgacaggagggccacatccttggcatggcaccca
actcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaacttt
ggcataaaggacaaacccaccttcattaaagggatcggagctggagggagcatcactggg
ctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacactctccgagtttttaccagctcaggcacctgcaac
ttctggttttgcagcctggatgtgtctgccagaagccgaatggtggtcacgggagacaat
gtggggcacgtgatcctgctcaacatggatggcagggagctttggaatctgagaatgcac
aaaaagaaagtgacccatgtggccctgaacccatgctgtgattggttcctggccacagcc
tctgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccactcgctgccgcatagccatcctgtcaacgcagcttgtttcagtcctgatggagcc
cagctcctgaccactgaccagaagagtgagctccgggtttactcggcctcccagtgggac
tgccccccaagcctgatcccacaccctcaccgccacttccagcacctgacgcccatcaag
gcaacctggcatcctcggtacaacctcgttgtcgtgggccgatacccagatcctaatttc
aaaagctgtaccccccatgaattaaggacgatcgatgtgtttgatggaaactcagggaag
atgatgtatcagctctatgacccagaatcttctggtatcatttcgctcaatgagttcaat
cccatgggggacacgctggcctctgtgatgggttatcacattctcatttggagccaggag
gaagctgggatgcggacatga

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