Mycobacterium avium subsp. paratuberculosis E93: RE97_06355
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Entry
RE97_06355 CDS
T03847
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mavu
Mycobacterium avium subsp. paratuberculosis E93
Pathway
mavu00020
Citrate cycle (TCA cycle)
mavu00630
Glyoxylate and dicarboxylate metabolism
mavu00785
Lipoic acid metabolism
mavu01100
Metabolic pathways
mavu01110
Biosynthesis of secondary metabolites
mavu01120
Microbial metabolism in diverse environments
mavu01200
Carbon metabolism
mavu01210
2-Oxocarboxylic acid metabolism
Module
mavu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mavu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mavu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
RE97_06355 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
RE97_06355 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
RE97_06355 (kgd)
Enzymes [BR:
mavu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
RE97_06355 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
RE97_06355 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
RE97_06355 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
RE97_06355 (kgd)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AJK78848
LinkDB
All DBs
Position
complement(1345842..1349564)
Genome browser
AA seq
1240 aa
AA seq
DB search
MSNISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPTGDSVLAAPASTDGPS
APAPAPCPPKRPRRLRPPSRPGPRPSPPPAPGNGASTRPAKPATPPPAEGDELQTLRGAA
AAVVKNMSASLEVPTATSVRAIPAKLLIDNRIVINNQLKRTRGGKISFTHLLGYALVQAI
KKFPNMNRHYAEIDGKPTAITPAHTNLGLAIDLQGKDGKRSLVVAGIKNCETMRFAQFVT
AYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMNGQGAIIGVGAMEYPAEF
QGASEERIAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHEMLLSDGFWDDIFRELSIP
YLPIRWSTDNPDSIVDKNARVMELIAAYRNRGHLMADIDPLRLDGSRFRSHPDLEILNHG
LTLWDLDRVFKVNGFAGAEYKKLRDILGLLRDAYCRHIGVEYTHILDPEQQEWLQQRVET
KHVKPTVAEQKFILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHG
LDEVVIGMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPAQAHGSGDVKYHLGATGVYLQM
FGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLDHGADDQGDEKAFSVVPMMLHGDAA
FAGQGVVAETLNLTHLPGYRVGGTIHIIVNNQIGFTTAPEHSRSSEYCTDVAKMIGAPIF
HVNGDDPEACAWVAKLAVDFRQKFKKDVVIDMLCYRKRGHNEGDDPSMTNPAMYDVVDIK
RGVRKSYTEALIGRGDISMKEAEDALRDYQGQLERVFNEVRELEKHGVGPSESVEADQML
PAGLATAVDKALLARIGDAFLALPEGFTAHPRVQPVLEKRREMAYEGKIDWAFAELLALG
SLVAGGKLVRLSGQDTRRGTFSQRHSVIIDRNTGEEFTPLQLLATNPDGTPTGGKFLVYD
SPLSEYAAVGFEYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVL
LLPHGHEGQGPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIKRPLIVF
TPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDGIGDRGKVSRVLLTSGKLYYELVARK
NKDNRDDVAIVRIEQLAPLPKRRLGETLDRYPNVREYFWVQEEPANQGAWPRFGLELPEL
LPDKLTGLKRISRRAMSAPSSGSSKVHAVEQQEIIDTAFA
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
gtgagcaacataagttcaccattcgggcagaacgaatggctggtcgaggagatgtaccgc
aagttccgcgacgacccctcgtcggtcgatccgagctggcacgaattcctcgtcgactac
aaccccgagcccaccggcgactcggtgctggccgccccggccagcaccgacggcccgtcc
gccccggcgccggcgccctgcccgcccaaacggccccgccggctcagaccgcccagccgg
cccggcccgcgccccagcccgccgccggccccgggcaacggggcgagcacccgcccggcc
aagcccgccactcccccgccggccgagggtgacgagctgcagacgttgcgcggcgccgcc
gcggccgtcgtcaagaacatgtccgcgtcgctggaggtgccgacggccaccagcgtgcgc
gccatcccggccaaactgctgatcgacaaccggatcgtcatcaacaaccagctcaagcgc
acccgcggcggcaagatctcgttcactcacctgttgggctacgcgctggtgcaggcgatc
aagaagttcccgaacatgaatcggcactacgccgagatcgacggcaaacccaccgcgatc
accccggcgcacaccaacctgggcctggccatcgatctgcagggcaaggacggcaagcgg
tcgttggtggtggccggcatcaagaactgcgagaccatgcggttcgcccagttcgtcacc
gcctacgaggacatcgtgcggcgggcccgcgacggcaagctgaccgccgaagactttgcc
ggcgtgacgatttcgctcaccaaccccggcaccatcggcaccgtgcactcggtgccgcgg
ctgatgaacggccagggcgccatcatcggcgtgggcgcgatggagtaccccgccgaattc
cagggggccagcgaggaacgcatcgccgaactgggcatcggcaagctgatcacactgacc
tcgacctacgaccaccgcatcatccagggcgcggaatccggtgacttcctgcgcaccatc
cacgagatgctgctgtcggacgggttctgggacgacatcttccgcgagctgagcatcccg
tacctgccgatccggtggagcaccgacaacccggactcgatcgtcgacaagaacgcccgg
gtgatggagttgatcgcggcctaccgcaaccgcgggcacctgatggccgacatcgacccg
ctgcggttggacggcagccggttccgcagccaccccgatctggagatcctcaaccacggc
ctgacgctgtgggacctggaccgggtgttcaaggtcaacggcttcgccggggcggagtac
aagaagctgcgcgacatcctgggcctgctgcgggatgcgtactgccgccacatcggcgtg
gagtacacccacatcctcgaccccgagcagcaggaatggctgcagcagcgggtcgagacc
aaacacgtcaagccgacggtggccgagcagaagttcatcctgagcaagctgaacgcggcc
gaggccttcgagaccttcttgcagaccaaatacgttgggcagaaacgcttttcgctggaa
ggcgcggaaagtgtgatcccgatgatggacgcggcgatcgatcagtgcgccgagcacggg
ctcgacgaagtggtgatcgggatgccgcaccgcggccggctcaacgtgctggccaacatc
gtcggcaagccgtactcgcagatcttctccgagttcgagggcaacctcaacccggcgcag
gcgcacggctccggcgacgtcaagtaccacctgggcgccaccggcgtgtacctacagatg
ttcggcgacaacgacattcaggtgtcgttgaccgccaacccgtcgcacctggaggccgtc
gacccggtgctggagggtctggtccgggccaagcaggacctgctggatcacggcgccgac
gaccagggagacgagaaggccttctcggtggtgccgatgatgctgcacggcgatgccgcg
ttcgccggccagggcgtggtggccgagacactgaacctgacccatctgcccggctaccgg
gtcggcggcaccatccacatcatcgtcaacaaccagatcggcttcaccacggcgccggag
cactcccgctccagcgagtactgcaccgacgtcgccaagatgatcggggcccccatcttc
cacgtcaacggcgacgacccggaggcctgcgcgtgggtggccaagctggccgtcgacttc
cggcagaaattcaagaaggacgtcgtcatcgacatgctgtgctaccgcaagcgcgggcac
aacgagggcgacgacccgtcgatgaccaacccggccatgtacgacgtcgtcgacatcaag
cgcggggtgcgcaagagctacaccgaggcgctgatcggccgcggcgacatctcgatgaaa
gaggccgaggacgcgctgcgcgactaccagggccagctggagcgggtgttcaacgaggtc
cgcgaactggagaagcacggcgtggggcccagcgagtcggtggaagccgaccagatgctg
cccgcgggcctggccaccgcggtggacaaggcgctgctggcccgcatcggcgacgcgttc
ctggcgctgccggagggtttcaccgcccaccctcgggtgcagccggtactggagaagcgc
cgggagatggcctacgagggcaagatcgactgggccttcgccgaactgctggcgctgggc
tcgctggtggccgggggcaagctggtgcggctgtccgggcaggacacccggcgcggcacc
ttctcgcaacggcactcggtgatcatcgaccgcaacaccggcgaggagttcaccccgctg
cagttgctggcgaccaaccccgacggcaccccgaccggcggcaaattcctggtgtatgac
tccccgctgtcggagtacgcggccgtcggcttcgagtacggctacaccgtgggcaacccc
gacgccctggtgctgtgggaggcgcagttcggcgacttcgtcaacggcgcgcagtcgatc
atcgacgagttcatcagctcgggtgaggccaagtggggtcagctgtccaacgtcgtgctg
ttgctgccgcacgggcacgagggccagggccccgaccacacctcggcgcgcatcgagcgc
ttcctgcagctgtgggcggaggggtcgatgacgatcgcgatgccgtccaccccgtccaac
tacttccacctgttgcgccggcacgccctggacgggatcaagcggccgctgatcgtgttc
accccgaagtcgatgctgcgcaacaaggccgcggtcagcgacatcaaggacttcaccgag
atcaagttccgctcggtgctcgaggagccgacctacgaggacggcatcggcgatcgcggc
aaggtcagccgggtgctgttgaccagcggcaagctctactacgagctggtcgcgcgcaag
aacaaggacaaccgcgacgacgtggcgatcgtgcggatcgaacagctggccccgctgccc
aagcgccggctgggcgagacgctggaccgctatccgaacgtgcgcgagtacttctgggtg
caggaggagccggccaaccagggggcctggccgcgattcggcctggagctgcccgagctg
ctgcccgacaagctgaccgggctcaagcggatttcccgccgggcgatgtcggcgccgtcg
tcgggctcgtcgaaggtgcacgccgtcgagcagcaggagatcatcgacaccgccttcgcc
tga
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