Mus caroli (Ryukyu mouse): 110304299
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Entry
110304299 CDS
T05910
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal04140
Autophagy - animal
mcal04141
Protein processing in endoplasmic reticulum
mcal04210
Apoptosis
mcal04932
Non-alcoholic fatty liver disease
mcal05010
Alzheimer disease
mcal05012
Parkinson disease
mcal05014
Amyotrophic lateral sclerosis
mcal05016
Huntington disease
mcal05017
Spinocerebellar ataxia
mcal05022
Pathways of neurodegeneration - multiple diseases
mcal05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
110304299 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110304299 (Ern1)
09143 Cell growth and death
04210 Apoptosis
110304299 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
110304299 (Ern1)
05012 Parkinson disease
110304299 (Ern1)
05014 Amyotrophic lateral sclerosis
110304299 (Ern1)
05016 Huntington disease
110304299 (Ern1)
05017 Spinocerebellar ataxia
110304299 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
110304299 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110304299 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
110304299 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcal01001
]
110304299 (Ern1)
Enzymes [BR:
mcal01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110304299 (Ern1)
Protein kinases [BR:
mcal01001
]
Serine/threonine kinases: Other
IRE family
110304299 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
110304299
NCBI-ProteinID:
XP_021031230
Ensembl:
MGP_CAROLIEiJ_G0017324
UniProt:
A0A6P5QRL8
LinkDB
All DBs
Position
11:complement(102296690..102389750)
Genome browser
AA seq
977 aa
AA seq
DB search
MPARWLLLLLALLLQPPGPGSFGRASTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLR
KVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINIVGQTSDNTPTTV
SQDVEEKLSRAPAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQRQLQHQQ
LQKELEKIHLLQQQQLPFHPHGDLAQDPEFLGSSGPFSESSGTSSPSPSPRASNHSLHSS
SSASRAGTSPSLEQDDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAV
GRHSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGNHPFGKSLQ
RQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPVEVQETLGSIPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQTY
YWHEPTEPQPPVIPDVL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggtggctgttgctcctgctggcgctgctgctacagccgcccggccccggg
agttttggaagagccagcacagtaacactgcctgagaccttgttgtttgtctcaaccctg
gatggaagcttgcatgctgtcagcaagaggacgggctccatcaagtggactttaaaagaa
gatccagtcctgcaggtcccgacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacacttggaggcaagaacaacgaaggcctgacgaaacttcccttt
accatcccagaattagttcaggcctccccatgccgaagttcagatggaatcctctacatg
ggtaaaaagcaagatatttggtatgttatcgacctcctgactggcgagaagcagcagact
ttgtcatcggcctttgctgatagtctctgcccatcaacttcccttctatatcttggacgg
acagagtacaccatcaccatgtatgacaccaagacccgggagctccgctggaatgccacc
tattttgactatgcagcctcactgccggaagatgacgtggactacaagatgtcccacttt
gtgtccaatggcgatggactggtggtaactgtggacagtgaatctggggatgtcttgtgg
atccaaaactatgcctctcctgtggtggccttctacatctggcagcgggagggcctgaga
aaggtggtgcacatcaacgttgctgtggagactctacgctacttgaccttcatgtctggg
gaagtggggcgcatcaccaagtggaagtatccattccccaaggagacagaggccaagagc
aagctaacgcctactctgtatgttgggaagtattccaccagcctctatgcctctccctca
atggtgcatgagggggttgctgtcgtgcctcgaggcagcactcttcctttgctggaaggc
ccccagacagatggtgtcaccattggagacaaaggagagtgtgtgatcactcccagcaca
gacctcaagtttgaccctggactcaaagggaagagcaagctgaactacttgaggaattac
tggcttctcataggacaccatgaaactcctctgtctgcatccaccaagatgctggagaga
tttcctaacaacctgcccaaacatcgagaaaatgtgattcctgctgattcagaaaaaagg
agctttgaggaagttatcaacatagttggccagacttcagacaacacaccgaccaccgta
tctcaggatgtggaggagaagctctctcgtgcccctgccaagcctgaggcccccgtggac
tccatgctcaaggacatggctacgattatcctgagcaccttcctgctggttggatgggtg
gcgttcatcatcacttatcccttgagcatgcatcagcagcgtcagctccagcaccaacag
ttgcagaaggagctggagaagattcatctcctgcagcagcagcagctgcccttccatcca
cacggagaccttgcccaggaccccgagttcctgggttcatctggccccttctcagagagc
tcgggcaccagcagccccagcccatcccccagagcctccaaccactccctccactccagc
agctctgcctccagggccggcaccagcccctctctggagcaggatgatgaggatgaggaa
accagaatggtgattgttgggaaaatttcattctgccccaaggatgtcctgggtcatgga
gctgagggcacaattgtatacaaaggtatgtttgacaaccgagatgtggccgtgaagagg
atcctccctgagtgttttagctttgccgaccgtgaggtccagctgcttcgagaatcagac
gagcacccaaatgtgatccgctacttttgcacagagaaggaccggcagttccagtacatt
gccattgagctgtgtgcagccaccctacaagagtatgtggagcagaaggactttgcccac
cttggcctagagcccatcaccctgcttcatcaaaccacctcaggcctggcacacctgcat
tctctcaacattgttcacagagacctgaagccccacaacattctcctctccatgcccaac
gcacatggcaggatcaaggcgatgatctctgactttggcctctgcaagaagctggcagtg
ggcaggcacagtttcagccgccgttcaggggtacctggcactgaagggtggatcgcccca
gagatgctgagtgaagactgtaaggacaaccctacctacacggtggacatcttttctgca
ggctgtgtcttttactatgtcatctctgagggcaaccatccttttggcaaatccttgcag
cggcaggccaacatcctcctgggcgcctgcaaccttgactgcttccactcagacaagcat
gaggacgtcattgctcgtgaattgatagagaaaatgattgcaatggatccccagcagcgt
ccctctgcaaagcacgtgctgaaacaccccttcttctggagcctggagaagcagctccag
tttttccaggatgtaagtgaccgaatagaaaaggaggccttagacggtccaatcgtacgg
cagttggagagaggcgggagagctgtggtcaagatggactggcgggagaacatcactgtc
cccctgcagacagatctgcgcaaattcagaacgtacaaaggtggctctgtcagagatctc
ctccgagccatgagaaacaagaaacaccactaccgggagctccctgtggaggttcaagag
acgctgggctccatcccagatgactttgtgcgttacttcacttcccgcttcccccacctc
ctctctcacacctaccaagccatggagctgtgcagacacgagagactcttccagacctac
tactggcacgagcccacagaaccccagcctccagtgattccagatgtcctctga
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