Macaca mulatta (rhesus monkey): 695328 Help Entry 695328            CDS       T01028                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc00230   Purine metabolism mcc01100   Metabolic pathways mcc01522   Endocrine resistance mcc04015   Rap1 signaling pathway mcc04020   Calcium signaling pathway mcc04022   cGMP-PKG signaling pathway mcc04024   cAMP signaling pathway mcc04062   Chemokine signaling pathway mcc04072   Phospholipase D signaling pathway mcc04114   Oocyte meiosis mcc04211   Longevity regulating pathway mcc04213   Longevity regulating pathway - multiple species mcc04261   Adrenergic signaling in cardiomyocytes mcc04270   Vascular smooth muscle contraction mcc04371   Apelin signaling pathway mcc04540   Gap junction mcc04611   Platelet activation mcc04713   Circadian entrainment mcc04714   Thermogenesis mcc04723   Retrograde endocannabinoid signaling mcc04724   Glutamatergic synapse mcc04725   Cholinergic synapse mcc04727   GABAergic synapse mcc04750   Inflammatory mediator regulation of TRP channels mcc04911   Insulin secretion mcc04912   GnRH signaling pathway mcc04913   Ovarian steroidogenesis mcc04914   Progesterone-mediated oocyte maturation mcc04915   Estrogen signaling pathway mcc04916   Melanogenesis mcc04918   Thyroid hormone synthesis mcc04921   Oxytocin signaling pathway mcc04922   Glucagon signaling pathway mcc04923   Regulation of lipolysis in adipocytes mcc04925   Aldosterone synthesis and secretion mcc04926   Relaxin signaling pathway mcc04927   Cortisol synthesis and secretion mcc04928   Parathyroid hormone synthesis, secretion and action mcc04934   Cushing syndrome mcc04935   Growth hormone synthesis, secretion and action mcc04970   Salivary secretion mcc04971   Gastric acid secretion mcc04972   Pancreatic secretion mcc04976   Bile secretion mcc05032   Morphine addiction mcc05163   Human cytomegalovirus infection mcc05166   Human T-cell leukemia virus 1 infection mcc05200   Pathways in cancer mcc05207   Chemical carcinogenesis - receptor activation mcc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mcc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     695328 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     695328 (ADCY2)    04371 Apelin signaling pathway     695328 (ADCY2)    04020 Calcium signaling pathway     695328 (ADCY2)    04072 Phospholipase D signaling pathway     695328 (ADCY2)    04024 cAMP signaling pathway     695328 (ADCY2)    04022 cGMP-PKG signaling pathway     695328 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     695328 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     695328 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     695328 (ADCY2)    04062 Chemokine signaling pathway     695328 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     695328 (ADCY2)    04922 Glucagon signaling pathway     695328 (ADCY2)    04923 Regulation of lipolysis in adipocytes     695328 (ADCY2)    04912 GnRH signaling pathway     695328 (ADCY2)    04913 Ovarian steroidogenesis     695328 (ADCY2)    04915 Estrogen signaling pathway     695328 (ADCY2)    04914 Progesterone-mediated oocyte maturation     695328 (ADCY2)    04921 Oxytocin signaling pathway     695328 (ADCY2)    04926 Relaxin signaling pathway     695328 (ADCY2)    04935 Growth hormone synthesis, secretion and action     695328 (ADCY2)    04918 Thyroid hormone synthesis     695328 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     695328 (ADCY2)    04916 Melanogenesis     695328 (ADCY2)    04925 Aldosterone synthesis and secretion     695328 (ADCY2)    04927 Cortisol synthesis and secretion     695328 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     695328 (ADCY2)    04270 Vascular smooth muscle contraction     695328 (ADCY2)   09154 Digestive system    04970 Salivary secretion     695328 (ADCY2)    04971 Gastric acid secretion     695328 (ADCY2)    04972 Pancreatic secretion     695328 (ADCY2)    04976 Bile secretion     695328 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     695328 (ADCY2)    04727 GABAergic synapse     695328 (ADCY2)    04725 Cholinergic synapse     695328 (ADCY2)    04723 Retrograde endocannabinoid signaling     695328 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     695328 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     695328 (ADCY2)    04213 Longevity regulating pathway - multiple species     695328 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     695328 (ADCY2)    04714 Thermogenesis     695328 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     695328 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     695328 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     695328 (ADCY2)    05163 Human cytomegalovirus infection     695328 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     695328 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     695328 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     695328 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     695328 (ADCY2) Enzymes [BR:mcc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      695328 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  695328 NCBI-ProteinID:  NP_001252581 Ensembl:  ENSMMUG00000018742 UniProt:  A0A1D5RHE7 LinkDB All DBs Position 6:7279352..7704736 Genome browser AA seq 1091 aa AA seqDB search MWQQAMRRRRYLRDRAEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLA LLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAM GYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSAT PGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQ ERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFT RLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVK MGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGG VPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPR HTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTL RTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAF KYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASP LLMWLLKSSGIIANRPWPRISLTIITTAIILTMAVFNMFFLSDSEETIPPTANTTNTSFS ASNNQAAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHT HAHVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKK EREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEDLYHQSYDCVCVMFASIPDFKEFY TESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHA QEPERQYMHIGTMVEFAFALVAKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDI WGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEM SRSLSQSNVAS NT seq 3276 nt NT seq  +upstreamnt  +downstreamnt atgtggcagcaggcgatgcggcgccgccgctacctgcgggaccgcgccgaggaggcggcg ggcggcggagacgggctgccgcggtcccgggactggctctacgagtcctactactgcatg agccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgcc ctgctcgccgtcttcttcgcgctcgggctggaagttgaagaccatgtggcgtttctaata acagttccgaccgccctggcgattttctttgcgatatttatcctggtctgcatagagtct gtgtttaagaaactgctgcgcctcttctcgttggtgatatggatatgccttgttgccatg ggatacctgttcatgtgttttggaggtaccgtctctccctgggaccaggtatcgttcttc ctcttcatcatcttcgtggtgtacaccatgctgcccttcaacatgcgagacgccatcatt gccagtgtcctcacctcctcctcccacaccatcgtgcttagcgtctgcctgtctgcaacg ccgggaggcaaggagcacctggtctggcagatcctggccaatgtgatcattttcatctgt gggaacctggcgggagcctaccataagcacctcatggaacttgctcttcagcaaacatat caggacacctgtaattgcatcaagtcccggatcaagttggaatttgaaaaacgtcaacag gagcggcttctgctctccctgctgccggcccacatcgccatggagatgaaagcggagatc atccagaggttgcagggccccaaggcaggccagatggagaacacaaataacttccacaac ctgtacgtgaagcggcataccaacgtgagcatcttatacgctgacattgttggctttacc cggctggcaagtgactgctccccaggagaactagttcacatgctgaatgagctcttcgga aagtttgatcaaattgcaaaggagaatgaatgcatgagaattaaaattttaggagactgc tactactgtgtatctggactccctatatctctccctaaccatgccaagaactgtgtgaaa atgggactggacatgtgtgaagccataaagaaagtgagggatgctactggagttgatatc aatatgcgtgtgggcgtgcattctgggaacgtcctgtgcggcgtgattggtctgcagaag tggcagtatgatgtgtggtcacatgacgtgaccttggccaaccacatggaagctggaggg gtccctggacgtgttcacatttcttccgtcaccctggagcacttgaatggcgcttataaa gtggaggagggagatggtgacattagggacccatatttaaagcagcacctggtgaaaacc tactttgtaatcaaccccaagggagaacgacggagcccccagcatctcttcagacctcgc cacaccctcgacggagccaaaatgagggcctcggtccgcatgacccggtacttggagtcc tggggggcggccaagccctttgcacacctacatcacagggacagcatgaccacagagaac ggcaagatcagcaccacggatgtacccatgggtcagcataattttcaaaatcgcacctta agaaccaagtcacaaaagaaaagatttgaagaagaattgaatgaaaggatgattcaagca attgatgggattaatgcacaaaagcaatggctcaagtctgaagacattcagagaatctca ctgcttttctataacaaagtactagaaaaagagtaccgggccacggcactgccagcattc aagtattacgtgacttgtgcctgtctcatattcttctgtatcttcattgtgcagattctc gtgctgccaaaaacgtccgtcctgggcatctcctttggggctgcgtttctcttgctggcc ttcatcctcttcgtctgctttgctggacagcttctgcaatgcagcaaaaaagcctctccc ctgctcatgtggcttttgaagtcctcaggcatcattgccaaccgaccctggccacggatc tctctcacgatcatcactacagccatcattttaaccatggccgtgttcaacatgtttttc ctgagtgactcagaggaaacaatccctccaactgccaatacaacaaacacaagcttttca gcctcaaataatcaggcggcgattctgcgtgcgcaaaatttatttttcctcccgtacttt atctacagctgcattctgggactgatatcctgttccgtgttcctgcgggtgaactacgag ctgaagatgttgatcatgatggtggcgttggtgggctacaacaccatcctacttcacacc cacgcccacgtcctgggcgactacagccaggtcttgtttgagagaccaggcatttggaaa gacctgaagactatgggctctgtgtctctctctatattcttcatcacactgcttgttctg ggtagacagaatgaatattactgtaggttagacttcttatggaagaacaagttcaaaaaa gagcgggaggagatagagaccatggagaacctgaaccgtgtgctgctggagaacgtgctt cccgcacacgtcgctgagcacttcctggccaggagcctgaagaatgaggatctataccac cagtcctatgactgtgtctgcgtcatgtttgcctccattccggatttcaaagaattttat acagaatccgacgtgaacaaggagggcttggaatgccttcggctcctgaacgagatcatc gctgactttgatgatcttctttccaagccaaaattcagtggagttgaaaagattaagacc attggcagcacatacatggcagcaacaggtctgagcgctgtgcccagccaggagcacgcc caggagcccgagcggcagtacatgcacattggcaccatggtggagtttgcctttgccctg gtagcgaagctggatgccatcaacaagcactccttcaacgacttcaaattgcgagtaggt attaaccatggacctgtgatagctggtgtgattggagctcagaagccacaatatgatatc tggggcaacactgtcaatgtggccagtaggatggacagcaccggagtcctggacaaaata caggttacggaggagacaagcctcgtcctgcagaccctcggatacacatgcacctgtcga ggaataatcaacgtgaaaggaaagggggacctgaagacgtactttgtaaacacagaaatg tcaaggtccctttcccagagcaatgtggcatcctga

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