Monodelphis domestica (gray short-tailed opossum): 100025680
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Entry
100025680 CDS
T01031
Symbol
LCK
Name
(RefSeq) LCK proto-oncogene, Src family tyrosine kinase
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
mdo
Monodelphis domestica (gray short-tailed opossum)
Pathway
mdo04064
NF-kappa B signaling pathway
mdo04380
Osteoclast differentiation
mdo04650
Natural killer cell mediated cytotoxicity
mdo04658
Th1 and Th2 cell differentiation
mdo04659
Th17 cell differentiation
mdo04660
T cell receptor signaling pathway
mdo05135
Yersinia infection
mdo05166
Human T-cell leukemia virus 1 infection
mdo05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mdo05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mdo00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100025680 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100025680 (LCK)
04660 T cell receptor signaling pathway
100025680 (LCK)
04658 Th1 and Th2 cell differentiation
100025680 (LCK)
04659 Th17 cell differentiation
100025680 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
100025680 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100025680 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100025680 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
100025680 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
100025680 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mdo01001
]
100025680 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mdo03036
]
100025680 (LCK)
Enzymes [BR:
mdo01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100025680 (LCK)
Protein kinases [BR:
mdo01001
]
Non-receptor tyrosine kinases
SRC family
100025680 (LCK)
Chromosome and associated proteins [BR:
mdo03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100025680 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
Kdo
SH3_3
SH3_16
Motif
Other DBs
NCBI-GeneID:
100025680
NCBI-ProteinID:
XP_007492945
Ensembl:
ENSMODG00000017464
LinkDB
All DBs
Position
4:425628199..425661445
Genome browser
AA seq
509 aa
AA seq
DB search
MGCCCSSSLDEDWMENIDVCERCHYPIVPLDAKDMLPMRNGSEVRDPLVDYNGLDPPVSP
LQDNLVIALHSYKPSHDGDLGFEKGEQLKILEQNGEWWKAQSLTTGQEGFIPFNFVAKVN
SLEPEPWFFKDLSRKDAERQLLAPGNTHGSFLIRESETTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVQHYSKVSDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKAGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTSTGVKLTIHKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTYGRIPYPGMTNPEVIQNLEQGYRMVRPDNCPEELYKLMMLCWKER
PEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgctgctgcagctccagcctcgatgaggactggatggaaaatatcgacgtgtgc
gaacgatgccactaccctattgttccattggatgctaaggacatgctcccaatgaggaat
ggttctgaagtgcgggatcccttggtcgactataatggcttagacccacctgtgtctccg
ttacaagataacctggtcatcgccctgcacagttataaaccctcccatgatggggacctg
ggctttgagaagggggagcagctcaagatcctggagcagaatggagaatggtggaaggca
cagtccctgaccactggccaggagggcttcattcccttcaattttgtggccaaagttaac
agcctggagcctgagccttggtttttcaaggacctgagtcggaaggatgctgagagacaa
cttctggcccctgggaacacccatggatccttcctgatcagagagagtgagacaactgca
ggttccttctcactctctgtgcgagactttgaccagaaccagggggaggtggtgaaacat
tacaagatccgcaatctggacaatggtggcttctacatttccccccgaatcacctttcct
ggtctgcatgagctggtccagcattactccaaagtctcagatgggctctgcactcgattg
agccggccctgccagacccagaaaccacagaagccctggtgggaagatgagtgggaggta
ccaagagagacgctgaagctggtggagaggctgggagctggccaatttggggaggtctgg
atggggtactataatggacacaccaaggtagctgtgaaaagcctaaaagcgggcagcatg
tcccctgatgccttcctggcagaggccaacctgatgaaacagttgcagcaccaacggctg
gtacgcctgtatgcagtggtcacgcaggagcccatctacatcatcactgaatacatggag
aacgggagcctcgtagacttcctcaaaacctcaacaggggtcaaactaaccatccacaaa
ttgctggatatggctgcacagattgctgagggcatggccttcattgaggagcggaattac
attcaccgagaccttcgggcagccaacatcctcgtgtcagacacactcagctgtaagatc
gctgactttggcttggcccggctaattgaggacaatgagtacacagctagggagggagca
aaatttcccatcaagtggacagctcctgaagccatcaactacgggacattcaccatcaag
tcagatgtctggtcttttggcatcctactaacagaaattgtcacctatgggaggattccc
tacccaggaatgaccaaccccgaggtgatccagaacctggagcagggttatcggatggtg
aggcctgacaactgcccagaggagctgtacaaactgatgatgttgtgctggaaggaaagg
cctgaggagcgacctacctttgactacttgaggagtgtattagaggacttcttcactgcc
acagagggccagtaccagccccagccatga
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