Methanobacterium sp. MB1: MBMB1_0015
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Entry
MBMB1_0015 CDS
T02957
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
meth
Methanobacterium sp. MB1
Pathway
meth00290
Valine, leucine and isoleucine biosynthesis
meth00620
Pyruvate metabolism
meth01100
Metabolic pathways
meth01110
Biosynthesis of secondary metabolites
meth01210
2-Oxocarboxylic acid metabolism
meth01230
Biosynthesis of amino acids
Module
meth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
meth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MBMB1_0015 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MBMB1_0015 (leuA)
Enzymes [BR:
meth01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
MBMB1_0015 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Replicase
Motif
Other DBs
NCBI-ProteinID:
CDG64135
UniProt:
U6E9N5
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All DBs
Position
13711..15246
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AA seq
511 aa
AA seq
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MYVDNVKKVMKIPEKVRIFDTTLRDGEQTPGVAITPEEKIRIAKRLDKLGVDVIEVGFPA
ASLGERKAAQEIKGLGLNAKVCGLARVLQEDLDAALDSDVDYIHTFIGTSPLHREYKLHM
DQEEILSKAVDAVEYIKDHGIIAEFSAEDATRTEFEFLKNIYKAVEEAGADVINVPDTVG
VMVPASMRQLVEDLREVVSIPISVHCHDDFGLAVANSLAAVEAGAQQVHATINGLGERAG
NTSLEEVVMTLMATYGIKTNITTELLVSTSELVSRITGVKMPPNKAIVGENAFAHEAGIH
VHGVLEKAETYEPLKPEMVGHTRRIVMGKHTGARAIKSKLDDYGIEMNEDQFCTLYDQVK
KLGDKGKMVTDADLQALAETVLGKPKEEKVKLEGFTVMTGDNVLPTATVKLNIDGKIKTA
AKTGVGPVDASINVIQELVRETADIELKEYHIEAITGGTNALAEVFVIMADEDGHSATGR
STVEDIVMASVEAVLDAINKILLARDMDESP
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgtatgtagataacgtaaagaaagtaatgaaaataccggaaaaggtgcgaatatttgat
accaccctccgtgacggtgaacaaacaccaggggtggcaataactccagaagaaaagata
agaatagccaagagactggataaattgggagtcgatgtgattgaagtcgggtttccagca
gcatcacttggtgaacggaaagcagcccaggaaattaagggtctaggtctgaatgcaaag
gtttgtggtttggcaagggtgctgcaggaagacttggacgcagccttagattcagatgtg
gattacattcacactttcattggaacctctcctcttcaccgagagtacaaactccacatg
gaccaagaagagatactcagcaaggctgtggatgccgtggagtacatcaaagaccatggg
attattgctgaattctcggcggaagatgccacccgaactgagttcgaatttttgaaaaac
atttacaaggcagtggaagaagcaggggccgatgtgatcaatgttccggacactgtggga
gttatggtaccggcttccatgcgccaattagtagaggatcttcgagaagtggtgagcata
cccatcagtgtgcactgccacgatgactttggcctggccgtggccaatagcttggctgca
gtggaagctggagcccagcaggtccacgccaccataaatggattaggagaaagggcaggt
aacacctccttagaagaagtggtaatgaccctaatggccacttatggtattaaaaccaac
ataaccaccgaacttttagtaagcacctcagaactagtttccagaataacaggggtgaaa
atgcccccaaacaaggccattgttggggaaaatgcctttgcccatgaagcaggaatacat
gtccatggagtcctggagaaagcagaaacttacgagccacttaaacctgaaatggtaggt
cacacccgtaggattgtaatgggaaaacatactggagcccgtgctatcaagtccaaactg
gatgattatggaattgaaatgaacgaagaccagttctgtaccctgtacgaccaggtaaag
aagctgggtgataagggtaaaatggttactgatgccgatctccaagccctagcagaaact
gtattaggtaagcctaaggaagaaaaggttaaactggaaggattcacagtgatgactggg
gataatgtcctacccacagccacagttaaactcaacattgatggaaagataaaaaccgct
gctaaaactggtgtaggtccagttgacgcatccattaatgtgatacaggagttagtccgt
gaaacagctgatatagaacttaaagaatatcatattgaagctataactggtggtactaat
gcactggctgaagtatttgtaataatggctgatgaagatgggcacagtgccacaggccgt
tctactgtggaagatatagttatggctagtgttgaggcggttttagatgctataaataag
atcctcttagcccgagatatggatgagtcaccgtga
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