Mycolicibacterium hassiacum: MHAS_02805
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Entry
MHAS_02805 CDS
T05715
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mhas
Mycolicibacterium hassiacum
Pathway
mhas00020
Citrate cycle (TCA cycle)
mhas00630
Glyoxylate and dicarboxylate metabolism
mhas00785
Lipoic acid metabolism
mhas01100
Metabolic pathways
mhas01110
Biosynthesis of secondary metabolites
mhas01120
Microbial metabolism in diverse environments
mhas01200
Carbon metabolism
mhas01210
2-Oxocarboxylic acid metabolism
Module
mhas_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mhas_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mhas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MHAS_02805 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MHAS_02805 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MHAS_02805 (kgd)
Enzymes [BR:
mhas01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MHAS_02805 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MHAS_02805 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MHAS_02805 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MHAS_02805 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
VCT91091
UniProt:
A0A3P3ZZZ4
LinkDB
All DBs
Position
1:2995203..2998913
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AA seq
1236 aa
AA seq
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MYRKFREDPSSVDPSWHEFLADYSPEPLNESSNGQPSNTTVTAPEPAPAPPPTPSPQPTA
TPAAQPAQAAPVQKPPVQKPPAQAAPVQKPPVQPTPAQAAPEKSQPAPGSSEDVRVLRGA
AAAVVKNMEASLEVPTATSVRAIPAKLMIDNRIVINNHLKRTRGGKISFTHLIGYAVVQA
VKKFPNMNRHYAEIDGKPTAVTPEHVNLGLAIDLQGKDGNRQLVVAGIKKAETLRFSQFV
AAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMRGQGAIIGVGAMEYPAE
FQGASEERIAELGVGKLVTLTSTYDHRIIQGAESGDFLRTVHELLLDDDFFDEIFRELGI
PYEPVRWRTDNPDPIEDKNARVMELIAAYRNRGHLMADIDPLRLDKDRFRSHPDLDVLTH
GLTLWDLDREFKVNGFAGAERKKLRDVLAVLRDAYCRHIGVEYTHILEPEQQKWLQERIE
GEHEKPTVAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAVIDQCAEH
GLDEVVIAMPHRGRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGASGTYIQ
MFGDNDIQVSLVANPSHLEAVDPVVEGLVRAKQDMLDKEGDDRFSVVPLVLHGDAAFAGQ
GVVAETLNMALLRGYRTGGTIHIIVNNQIGFTTSPDDAKSSEYCTDVAKMVGAPIFHVNG
DDPEAATWVARLAVDFRQKFHKDVVIDMICYRRRGHNEGDDPSMTQPKMYDAIDVKRGVR
KSYTEALIGRGDISLKEAEDALRDYQGQLERVFNEVRELEKHPVEPSESVEADQMIPRGL
PTGIDKSLLARIGDAHMALPEGFNVHPRVKPVLEKRREMAYEGKIDWAFAELLALGSLVA
EGKTVRLSGQDSRRGTFSQRHAVIIDRKTGEEFTPLQLLTRDPDGNPTGGKFYVYDSPLS
EFAAVGFEYGYSVGNPNALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPH
GHEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHALDGIRRPLIVFTPKS
MLRNKAAVSDIRDFTESKFRSVLEEPVYTDGDGDRNKVRRLLLCSGKLYYELAARKAKDG
RDDVAIVRIEQLAPLPRRRIAETLDRYPNVEEKFWVQEEPANQGAWPTFGLTLPEVLPDY
FTGLRRISRRAMSAPSSGSSKVHAVEQQEIIDEAFA
NT seq
3711 nt
NT seq
+upstream
nt +downstream
nt
atgtatcgcaagttccgcgaggacccctcctcggtagatccgagttggcatgagttcctc
gccgactactctcccgagccactcaacgaaagcagcaacggtcaacccagcaacacgacg
gtgacggcgcccgagccggcgcccgcacccccgcccacacccagtccgcaacccaccgcc
acacccgcggctcaacccgcccaggcggccccggtccagaagcccccagttcagaagccg
ccggcccaggcggccccggtccagaagcccccagttcagccgaccccggcccaggcggcc
cccgagaagtctcagccggcccccggctcgagcgaggacgtgcgggtgctgcgcggggcg
gcggccgcggtggtcaagaacatggaggcctcgctggaggtcccgaccgccaccagcgtg
cgcgccattccggccaagttgatgatcgacaaccgcatcgtcatcaacaaccacctgaaa
cgcactcggggcgggaagatctcgttcacccacctgatcggctacgcggttgtgcaggcg
gtcaagaagttcccgaacatgaaccgccactacgccgagatcgacggcaagccgaccgcg
gtcaccccggagcacgtgaacctgggcctggccatcgacctgcagggtaaggacggcaac
cgtcagctcgtggtggccggcatcaagaaagccgagaccctgcggttcagccagttcgtc
gccgcctacgaggacatcgtgcggcgcgcccgcgacggcaagctcaccgctgaagacttt
gcgggcgtgacgatttcgctcaccaacccgggcaccatcggcaccgtgcactcggtgccg
cggctgatgcggggccagggcgcgatcatcggcgtgggcgcgatggagtacccggcggaa
ttccagggcgccagcgaggaacgcatcgccgagctcggcgtgggcaagctggtgacgctg
acgtcgacctacgaccaccgcatcatccagggcgcagagtcgggcgacttcctgcgcacg
gtgcacgagctgctgctcgacgacgacttcttcgacgagatcttccgcgagctcggcatc
ccgtacgagccggtgcggtggcgcaccgacaaccccgacccgatcgaggacaagaacgcg
cgggtcatggagctgatcgcggcctaccgcaaccgcggtcacctgatggccgacatcgac
ccgctgcggctggacaaggaccggttccgcagccaccccgacctcgacgtgctcacccac
gggctgacgctgtgggatctcgaccgcgagttcaaggtcaacgggttcgccggcgcggag
cgcaagaaactgcgcgacgtgctcgcggtgctgcgcgacgcctactgccgccacatcggg
gtggagtacacccacatcctcgagccggagcagcagaagtggctgcaggagcgcatcgag
ggcgagcacgagaagccgaccgtcgcgcagcagaagtacatcctgagcaagctcaacgcc
gccgaggcgttcgagaccttcctgcagacgaaatacgttgggcagaagcgtttctcgctg
gaaggtgcggagaccgtcatcccgatgatggatgcggtgatcgaccagtgcgccgagcac
ggtctcgacgaggtcgtcatcgcgatgccgcaccgcggccgcctcaatgtgctggccaac
atcgtcggcaagccgtacagccagatcttcagcgagttcgagggcaacctgaacccgtcg
caggcgcacggctccggcgacgtcaagtaccacctgggcgccagcggaacttatatccag
atgttcggcgacaacgacattcaggtgtcgttggtggccaacccgtcgcacctggaggcg
gtcgacccggtggtcgagggcctggtgcgcgccaagcaggacatgctggacaaggagggt
gacgaccggttcagcgtggtcccgctggtgctgcacggcgatgccgcgttcgccggtcag
ggcgtggtggccgagacgctgaacatggcgctgctgcgcggctaccggaccggcggcacg
atccacatcatcgtcaacaaccagatcgggttcaccacctcgcccgacgacgccaagtcc
tcggagtactgcaccgacgtcgcgaagatggtcggcgccccgatcttccacgtcaacggc
gacgacccggaggccgccacctgggtggcgcggctggccgtggacttccggcagaagttc
cacaaggacgtcgtcatcgacatgatctgctaccggcggcgcggccacaacgagggcgac
gacccgtcgatgacccagccgaagatgtacgacgccatcgacgtcaaacgcggtgtgcgc
aagagctacaccgaggcgttgatcggccgcggcgacatctcgctcaaagaggccgaggac
gcgttgcgcgactaccagggccagttggaacgggtcttcaacgaggtgcgcgaactcgag
aaacacccggtcgaaccgagcgagtcggtggaggccgaccagatgatcccgcgcgggctg
ccgaccgggatcgacaagtcgctgctggcccgcatcggggacgcccacatggcgctgccc
gagggcttcaacgtgcacccgcgggtcaagccggtgctcgagaagcgccgcgaaatggcc
tacgagggcaagatcgactgggcgttcgcggagctgctcgcgctcggatcgctggtggcc
gagggcaagacggtgcggctcagcggccaggactcccgccgcggcacgttcagccagcgg
cacgcggtgatcatcgaccgcaagaccggcgaggagttcaccccgctgcagctgctgacc
cgcgacccggacggcaacccgaccggcggcaagttctacgtctacgactcgccgctgtcg
gagttcgccgccgtcggcttcgagtacgggtactccgtcggcaaccccaacgcgctggtg
ttgtgggaggcgcagttcggcgacttcgtcaacggggcgcagtcgatcatcgacgagttc
atctcctccggcgaggccaagtggggccagctctcggacgtggtgctgctgctgccgcac
ggccatgaggggcagggccccgaccacacctcaggccgcatcgagcggttcctgcagctg
tgggccgaggggtcgatgacgatcgcgatgccgtcgacgccggcgaactacttccacctg
ttgcgccggcacgcgctcgacgggatccgccggccgctgatcgtgttcacgccgaagtcg
atgctgcgcaacaaggccgcggtcagcgacatccgcgacttcaccgagtcgaagttccgc
tcggtgctcgaggagccggtgtacaccgacggcgacggcgaccggaacaaggtgcggcgg
ctgctgctgtgcagcggcaagctctactacgagctggccgcccgcaaggccaaggacggc
cgcgacgacgtggcgatcgtacggatcgaacagctggccccgctgccgcggcggcgcatc
gccgagacgctggaccgttaccccaacgtcgaggagaagttctgggtgcaggaggagccg
gcgaaccagggcgcgtggccgacgttcgggctgacgctgcccgaggtgctgccggactac
ttcaccgggctgcggcgcatctcgcggcgggcgatgtcggcgccgtcgtcggggtcgtcg
aaggtgcacgcggtcgagcagcaggagatcatcgacgaggcgttcgcctga
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