Marinithermus hydrothermalis: Marky_0398
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Entry
Marky_0398 CDS
T01457
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mhd
Marinithermus hydrothermalis
Pathway
mhd00470
D-Amino acid metabolism
mhd00550
Peptidoglycan biosynthesis
mhd01100
Metabolic pathways
mhd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mhd00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
Marky_0398
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Marky_0398
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Marky_0398
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mhd01011
]
Marky_0398
Enzymes [BR:
mhd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
Marky_0398
Peptidoglycan biosynthesis and degradation proteins [BR:
mhd01011
]
Precursor biosynthesis
Amino acid ligase
Marky_0398
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AEB11151
UniProt:
F2NKW2
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All DBs
Position
381187..382161
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AA seq
324 aa
AA seq
DB search
MSKLRILLIAGGRSGEHEVSLASARGVLEAMPHPTDLAVIAKDGRWLTGTAARAALEAGR
AQRGEHPFPPPLSWHRYDVAFPLLHGRWGEDGTIQGFLEMLGLPYVGAGVGAAALCMDKE
LTKRTLAHAGIPVVPWVSLWRGEGLPELPFSPPYFVKPANTGSSVGISKVRTREALGPAL
EEAFRWDDRVLVEQGLEGVRELEVALLGNVTAEASVVGEVRYQSEFYDYATKYTPGRAEL
LIPAPVDADVARRLQEVARTAYRLLGVRGLARVDFFLAPDGALYLNELNTMPGFTPTSMY
PKLWQASGLEYEALLERLVRLALE
NT seq
975 nt
NT seq
+upstream
nt +downstream
nt
atgagtaaattacgtatattactcatcgccggggggcgttcgggggagcacgaggtctcc
ctcgcctcggcgcggggggtgttggaggccatgccccaccccaccgacctcgcggtgatc
gcgaaggacgggcggtggcttacgggaactgccgcccgggcggcgctcgaggcgggccgg
gcgcagcgcggcgagcaccccttcccgccgcccctttcctggcatcgttacgacgtggcc
ttccccttgctgcacggccgttggggggaggacggcacgatccaggggtttttggagatg
ctggggctgccctacgtaggagccggggtgggggccgccgcgctatgcatggacaaggag
cttacgaaacgcaccctggcgcacgcgggcatccccgtggtgccttgggtgagcctgtgg
cgaggcgagggcctgcccgagctgcccttttccccgccgtacttcgtcaagcccgcgaac
actggctcgtccgtagggatctccaaggtgcgcacccgcgaggcgctcggaccggccctc
gaggaggccttccgctgggacgaccgggtcctggtggagcaggggctggagggggtgcgc
gagctcgaggtggcccttttgggcaacgtgacggccgaggcgagcgtggtgggggaggtc
cgttaccagagcgagttctacgattacgcgaccaagtacaccccgggacgggccgagctc
ctgattcccgcgcctgtagacgcggacgtggcgcgccgccttcaggaggtcgcccggacg
gcctaccgccttctcggggtgcgcggcctggcgcgcgtggacttcttcctcgccccggat
ggggcgctctacctcaacgagctcaacaccatgcccgggttcaccccgacgagcatgtac
cccaagctctggcaggcctcggggctggagtacgaagcgttgctcgagcggctcgtacgc
ctcgcgcttgagtga
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