Mycobacterium kansasii ATCC 12478: MKAN_06840
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Entry
MKAN_06840 CDS
T02887
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
mkn
Mycobacterium kansasii ATCC 12478
Pathway
mkn00020
Citrate cycle (TCA cycle)
mkn00630
Glyoxylate and dicarboxylate metabolism
mkn00785
Lipoic acid metabolism
mkn01100
Metabolic pathways
mkn01110
Biosynthesis of secondary metabolites
mkn01120
Microbial metabolism in diverse environments
mkn01200
Carbon metabolism
mkn01210
2-Oxocarboxylic acid metabolism
Module
mkn_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mkn_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
mkn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MKAN_06840 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
MKAN_06840 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MKAN_06840 (kgd)
Enzymes [BR:
mkn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
MKAN_06840 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
MKAN_06840 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
MKAN_06840 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
MKAN_06840 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AGZ50021
UniProt:
U5WQ29
LinkDB
All DBs
Position
1534696..1538385
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AA seq
1229 aa
AA seq
DB search
MANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLVDYNPEPAQSAPADNQQVATAPP
PEPVRPAAEPVRPATKPAGAAGAGNGSPAAAPTKAAAPPPAEGDELQVLRGAAAAVVKNM
SASLDVPTATSVRAVPAKLLIDNRIVINNQLKRNRGGKISFTHLLGYALVQAVKQFPNMN
RHYTEVDGKPNVVTPAHTNLGLAIDLQGKDGKRSLVVAGIKRCETMRFAQFVTAYEDIVR
RARDGKLTAEDFAGVTISLTNPGTIGTVHSVPRLMAGQGAIIGVGAMEYPAEFQGASQER
IAELGIGKLITLTSTYDHRIIQGAESGDFLRTIHQMLLADDFWDEIFRELGIPYLPVRWR
SDNPDSIVDKNPRVIELIAAYRNRGHLMADIDPLRLDKTRFRSHPDLDVCSHGLTLWDLD
RLFKVDGCFGGSPYMKLRDVLSILRDAYCRHVGVEYTHILEPEQQQWLQQRVEAKHVKPT
VAQQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVI
GMPHRGRLNVLANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGVYLQMFGDNDI
QVSLTANPSHLEAVDPVLEGLVRAKQDLLDSDGEQRFSVVPMMLHGDAAFAGQGVVAETL
NLTNLPGYRVGGTIHIIVNNQIGFTTAPEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACE
WVARLAVDFRQEFHKDVVIDMLCYRRRGHNEGDDPSMTNPYMYDVVDTKRGARKSYTEAL
IGRGDISLKEAEDALRDYQGQLERVFNEVRELEKHAVQPSMSVESEQQVPRGLATAVDKA
LLARIGDAFLAFPDGFTPHPRVQPVLEKRREMAYEGKIDWAFAELLALGSLVAEGKLVRL
SGQDTRRGTFSQRHSVIIDRNTGKEFWPLQLLATNKDGTPTGGKFLVYDSPLSEYAAVGF
EYGYTVGNPDALVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQGP
DHTSGRIERFLQLWAEGSMTIAVPSTPSNYFHLLRRHALDGIMRPLIVFTPKSMLRNKAA
VSDIKDFTEIKFRSVLEEPTYEDGIGDRSKVRRILLTSGKIYYELAARKAKDNRDDIAIV
RIEQLAPLPKRRLNETLDRYPNATEFFWVQEEPANQGAWPRFGLELPELLPDKLTGLKRI
SRRAMSAPSSGSSKVHAVEQQEILDTAFG
NT seq
3690 nt
NT seq
+upstream
nt +downstream
nt
gtggccaacataagttcaccgttcgggcaaaacgaatggctggtcgaggagatgtaccgc
aagttccgcgacgacccctcctcggtcgatccaagctggcacgaattcctggttgactac
aaccccgagccggctcagagcgccccggccgacaaccagcaagttgcgaccgccccgccg
cccgagcccgtccggcccgcggcagagcccgtccggcccgcgacaaagccggccggcgcc
gcgggcgcgggcaacggctcacccgccgctgctccaaccaaggccgctgcgccgccaccg
gccgagggcgacgagctgcaggtgctgcgcggcgccgcggcggccgtcgtcaagaacatg
tcggcgtcgctggacgtgccgacggcgaccagtgtccgtgccgtcccggccaagctgttg
atcgacaaccggatcgtcatcaacaaccagctcaagcgaaaccgcggcggcaagatctcg
ttcacccacctgctgggctatgcgctggtgcaagcggtcaagcagttccccaacatgaac
cgccattacaccgaggtcgacggcaagccgaatgtcgtcaccccggcgcataccaatctg
ggcctggcgatcgacctgcagggcaaagacggcaaacgctcactggtggtggccggtatc
aagcgctgcgagaccatgcgattcgcccagttcgtcaccgcctatgaagacatcgtgcgt
cgcgcccgtgatggcaagctgaccgccgaagactttgccggcgtgacgatttcgctgacc
aaccccggaaccatcggcaccgtgcactcggtgccgcggctgatggccgggcagggcgcc
atcatcggcgtcggcgccatggaatacccggccgagtttcagggagccagccaggagcgc
atcgccgagctgggcatcggcaaactgatcacgctgacgtcgacctacgaccaccgcatc
atccagggcgcggaatccggggacttcctgcgcaccatccaccagatgctgctcgccgac
gatttctgggacgagatcttccgtgagttgggcatcccctacctgccggtgcgctggcgc
tcggacaacccggactcgatcgtcgacaagaacccccgggtcatcgaactcattgccgcc
taccgcaaccgcggccacctgatggccgacatcgatccgctgcggctggacaaaacccgg
ttccgcagccaccccgacctcgacgtgtgctcccacgggctcacgctgtgggacctcgac
cggttgttcaaggtcgacggctgcttcggcggatcgccctatatgaagctgcgcgacgtg
ctctcgatactgcgcgacgcctactgtcgccacgtcggcgtggagtacacccacatcctc
gagcccgaacaacagcagtggctgcagcagcgggtcgaggccaaacacgtcaaaccgact
gtggcccaacagaaatacatcttgagcaagctcaatgccgccgaggcgttcgaaacgttc
ctgcagaccaagtacgtgggtcagaaacgattctcgctggagggcgccgaaagcgtgatc
ccgatgatggacgcggcgatcgaccagtgcgccgagcatggtctcgacgaggtggtcatc
gggatgccgcaccgcggccggctcaacgtgctggccaacatcgtcggcaagccgtactcg
cagatcttcaccgagttcgagggcaacctgaacccgtcgcaggcgcacggttccggcgac
gtcaagtaccacctcggcgccaccggggtgtacctgcagatgttcggcgacaacgacatt
caggtgtcgttgaccgccaacccgtcgcacctggaggctgtcgacccggtgctggagggc
ctggtgcgggccaagcaggatctgctggattccgacggcgaacagcgcttttccgtggtc
ccgatgatgttgcacggtgatgccgccttcgccggccagggtgtggtggccgagacgttg
aacctgaccaatctgcccggctaccgggtcggcgggaccatccacatcatcgtcaacaac
cagatcggtttcaccaccgcgccggaatattcgcggtccagcgagtactgcaccgatgtc
gccaagatgatcggcgcgccgatcttccacgtcaacggcgacgacccggaggcttgcgag
tgggtggcgcgcctggccgtggacttccggcaagaattccacaaggacgtcgtcatcgac
atgctgtgctatcggcgccgcgggcacaacgagggcgatgacccgtcgatgaccaacccc
tacatgtacgacgtcgtcgacaccaagcgcggggcccgcaagagctacaccgaagccctg
atcggccgcggcgacatctcgctcaaggaagccgaggatgcgctacgcgactaccagggc
cagctggagcgggtgttcaacgaggtccgcgagctggagaagcacgccgtgcaaccgagc
atgtcggtggagtccgagcagcaggttccacgcggcctggccaccgcggtggacaaagcg
ctgcttgcccgcatcggcgatgcgttcctggccttcccggacgggttcaccccgcatccg
cgcgtccaaccggtgctggaaaagcgccgggaaatggcctacgaaggcaagatcgactgg
gcgttcgccgaactgctggcgttggggtcgctggtggccgagggcaagctggtacggctc
tccgggcaggacacccgccgcggcacgttctcccaacggcattcggtgatcatcgaccgc
aacaccggcaaggagttctggccgctgcagctgctggccaccaacaaggacggcaccccc
accggcggcaagttcctggtctacgactcgccgttgtcggagtacgccgccgtcggcttc
gaatatggctacaccgtgggcaacccggatgccctggtgctgtgggaggcgcagttcggc
gatttcgtcaacggtgcacagtcgatcatcgacgaattcatcagctctggcgaggccaag
tggggccaattgtccaatgtggtgctgctgctgccgcacggacacgagggacaggggccc
gaccacacctccggccgaatcgagcgcttcctgcagctctgggcggaggggtcgatgacc
atcgcggtgccgtcgaccccgtcgaactacttccacctgctgcgccggcacgctctggac
gggatcatgcgcccactgatcgtgttcacgcccaagtcgatgctgcgcaacaaggccgcg
gtcagcgacatcaaggacttcaccgagatcaagttccgttcggtgttggaggaacccacc
tacgaagacggcatcggcgaccgcagtaaggtccggaggatcctgctgaccagcggcaag
atctattacgagctggccgcacgcaaggccaaggacaaccgcgacgacatcgcgattgtg
cgcatcgagcagctggccccgctacccaaacgccgtctcaacgagacgctggaccgctat
cccaatgccaccgaatttttctgggtgcaggaggagccggccaatcagggtgcctggccg
cggttcggcctggagctgccggagttgttgcccgacaagctgaccgggctcaagcggatt
tcgcgccgggccatgtcggcaccgtcgtcgggttcgtcgaaggtgcatgccgtcgagcag
caggagatcctcgacacggcgttcgggtag
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integrated database retrieval system
