Mycobacterium leprae Br4923: MLBr01678
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Entry
MLBr01678 CDS
T00842
Symbol
ddlA
Name
(GenBank) D-alanine-D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mlb
Mycobacterium leprae Br4923
Pathway
mlb00470
D-Amino acid metabolism
mlb00550
Peptidoglycan biosynthesis
mlb01100
Metabolic pathways
mlb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mlb00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
MLBr01678 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MLBr01678 (ddlA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MLBr01678 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mlb01011
]
MLBr01678 (ddlA)
Enzymes [BR:
mlb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
MLBr01678 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
mlb01011
]
Precursor biosynthesis
Amino acid ligase
MLBr01678 (ddlA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_3
RimK
ATPgrasp_ST
ATP-grasp_4
CPSase_L_D2
Motif
Other DBs
NCBI-ProteinID:
CAR71773
UniProt:
A0A0H3MR78
LinkDB
All DBs
Position
complement(2021746..2022900)
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AA seq
384 aa
AA seq
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MNVYQRPLMPWLPSGGRVRVAVVFGGRSNEHAVSCLSAGSILRNLDRQRFDVVAVGITPE
GTWMLTDPNPDALAIANRQLPAVSCESGIELTLPADPRRSGQLVSLSHGAGLGAGEVLTS
VDVVFPVLHGPYGEDGTIQGLLELARVPYVGAGVLASAAGMDKEFTKKLFAAEGLPLSAY
TVLRPLRPTLHRQECERLSLPVFVKPARGGSSIGISRVSSWGQLPSAIAYARRHDPKVIV
EAAVNGRELECGVLEMPDGTVAASAVGEIRVAGVSGSEDSFYDFTTKYLDDAAELDVPAK
VDDDVADEVRQLAIQAFRAIDCQGLARVDFFLTDDGPVINEINTMPGFTMTSMYPKLWAV
SSVDYPTLLATMVDTALARGVGMR
NT seq
1155 nt
NT seq
+upstream
nt +downstream
nt
gtgaatgtctaccagcggcccttgatgccttggctgccatccggcggccgtgtgcgcgtt
gccgtcgtattcggcgggcgcagtaacgaacacgccgtctcctgtctgtctgccggcagc
atcttgcgcaatctggatcgacagcggtttgacgtggtcgcggttggtatcactccggaa
gggacgtggatgctcaccgatcccaacccggatgcgctggcgattgccaatagacagctt
cccgctgtgagctgcgaatcgggaatcgagttgacgctgccggccgatccacggcgcagc
ggtcaactggtgtcactttcacacggcgccggccttggggccggagaggtcctgacgtcg
gtcgatgtggtattcccggtgttacatggtccatatggcgaggacggcaccatccagggg
ctgctggaactcgctcgtgtgccctacgtcggagctggtgttctggccagcgccgccggc
atggacaaggaattcactaagaagctcttcgctgcggagggactgccgttgagcgcgtac
acggtgttgcgtccgttgcggccaacgctgcatcggcaggagtgtgagcggttgagttta
ccggtattcgttaaacccgcacgcggtggctcgtctatcggtatcagccgggtgtcgagc
tggggtcaactgccctccgcgattgcctacgctcgccggcacgatccgaaggtgattgtc
gaggcggcggttaacggccgcgaactggagtgcggcgtgctcgaaatgccggatggcact
gtggcagccagcgcggtgggggaaattcgggtagccggggtgagcggaagcgaggattcg
ttctacgacttcaccaccaaatatctcgacgacgcagccgagttagatgtgcccgccaag
gtggacgatgacgttgctgacgaggtgcgccagctcgcgattcaggcgtttcgggctatc
gactgccagggcctggcacgagttgactttttcctaaccgacgacgggccggtgatcaat
gagatcaacacgatgccggggttcaccatgacctcgatgtacccaaagctgtgggcggtc
agtagcgtggactacccgacgttgctagcgaccatggtggatacggcattggctcggggt
gtgggtatgcgttag
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