Mycobacterium leprae Br4923: MLBr01942
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Entry
MLBr01942 CDS
T00842
Name
(GenBank) probable cholesterol dehydrogenase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
mlb
Mycobacterium leprae Br4923
Pathway
mlb00984
Steroid degradation
mlb01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
mlb00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
MLBr01942
Enzymes [BR:
mlb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
MLBr01942
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
MLBr01942
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
Polysacc_synt_2
KR
NmrA
adh_short
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
CAR72039
UniProt:
A0A0H3MRC3
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All DBs
Position
2327868..2328998
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AA seq
376 aa
AA seq
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MLRGVGNASLTTELGRVLVTGGSGFVGANLVTALLERGYQVRSFDRAPMPLPQHPQLEVL
QGDITDATVCTTAMDSIDTVFHTAAIIELMGGASVTDEYRQRSYTVNVGGTENLLRAGQK
SGVKRFVYTASNSVVMGGTPITGGDETMPYTKRFNDLYTETKVVAEKFVLSQNGVPDGET
MLTCSIRPSGIWGRGDQTMFRKAFESVVSGHVKVLIGSKNAKLDNSYVHNLVHGLILAAE
HLVPGGTAPGQAYFINDGEPINFFDFMGPIIKACGENWPRVRISGRLVRNVMAVWQRLHF
GFGLPKPPMEPLAVERVYLDNYFSIEKAHKELGYRPLFTTEQAMAECLPYYTELFEQIKV
AAKPHLASIAATPRPE
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atgcttcgcggcgtgggtaacgcatcgttgacgaccgagctcggacgcgtcttggtcacc
ggcggttcgggcttcgtcggcgctaatctggtgaccgccttgctggaacgcggataccag
gtacgctctttcgaccgcgccccgatgccgctgccgcagcacccgcagctggaggtgctg
caaggtgacatcaccgacgctacggtctgcactacagcgatggacagcatcgatacagtc
tttcacaccgcggcaatcatcgagctaatgggcggcgcttcggtgaccgacgagtatcgg
cagcgcagctacacggtcaacgtgggcggtaccgaaaacttgctccgcgcaggacaaaag
tccggagtcaaacggttcgtctacaccgcatccaacagtgtggtgatggggggcactccc
atcaccgggggtgatgaaacaatgccctataccaagcggttcaacgacctgtacaccgaa
accaaagtggtcgccgaaaaattcgtactctcacaaaacggcgtacccgatggtgaaacc
atgctaacatgttcgatcagacccagtggcatatggggtcgcggcgaccagacaatgttc
cgtaaggcattcgaaagtgtcgtatccggtcacgtcaaggtactcatcgggagtaagaac
gccaaactggataactcctacgtgcacaacctggtgcacggcttaatcttggctgccgag
cacctggtcccaggcggcaccgcacctggacaagcctacttcatcaacgatggcgagccg
atcaacttcttcgatttcatggggccaatcatcaaggcgtgtggtgaaaattggccacgg
gtgcggatctccggtcggctggtgcgcaacgtgatggctgtgtggcagcggctacacttc
ggcttcgggcttccgaagcctccgatggaaccgcttgcggtagaacgagtttacctcgac
aactacttttccatcgaaaaggcgcacaaagagctgggctatcggccgctgttcactacc
gaacaggccatggctgaatgtctaccttactacacagagttattcgaacaaatcaaggtg
gctgccaagccccatttggcatccatagccgccaccccgcggcccgagtag
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