Mycobacterium leprae TN: ML2414
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Entry
ML2414 CDS
T00047
Symbol
hemL
Name
(GenBank) glutamate-1-semialdehyde aminotransferase
KO
K01845
glutamate-1-semialdehyde 2,1-aminomutase [EC:
5.4.3.8
]
Organism
mle
Mycobacterium leprae TN
Pathway
mle00860
Porphyrin metabolism
mle01100
Metabolic pathways
mle01110
Biosynthesis of secondary metabolites
mle01120
Microbial metabolism in diverse environments
mle01240
Biosynthesis of cofactors
Module
mle_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
ML2414 (hemL)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
mle01007
]
ML2414 (hemL)
Enzymes [BR:
mle01000
]
5. Isomerases
5.4 Intramolecular transferases
5.4.3 Transferring amino groups
5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase
ML2414 (hemL)
Amino acid related enzymes [BR:
mle01007
]
Aminotransferase (transaminase)
Class III
ML2414 (hemL)
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GFIT
Motif
Pfam:
Aminotran_3
Aminotran_1_2
Motif
Other DBs
NCBI-ProteinID:
CAC31930
Pasteur:
ML2414
UniProt:
P46716
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All DBs
Position
complement(2884704..2886044)
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AA seq
446 aa
AA seq
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MGSTDQATAPAGPAVSISAKLFEDACAVIPGGVNSPVRAFSAVGGTPLFITEARGCWLTD
ADGRRYVDLVCSWGPMILGHAHPAVVDAVATVAASGLSFGAPTPAETQLAAEIIGRMAPV
ERIRLVNSGTEATMSAVRLARGFTGRTKIIKFSGCYHGHVDALLADAGSGVATLSLPSSP
GVTGAAAADTIVLPYNDIEAVRQTFARLGDQIAAVITEASPGNMGVVPPAPGYNAALRAI
TAEHGALLIIDEVMTGFRVSRSGWYGLDPVAADLFIFGKVMSGGMPAAAFGGRAEVMERL
APLGPVYQAGTLSGNPVAMAAGLATLRAAADAVYATLDRNADRLVAMLSEALTDAGVPHQ
IPRAGNMFSVFFSEAPVTDFASACNSQVWRYPAFFHALLDAGVYPPCSTFEAWFVSAALD
DAAFGRIVDALPGAAAAAVAARHRES
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
gtgggcagcactgaccaggcaaccgcaccggccggcccagccgtaagcatttcggcgaag
ctgtttgaggatgcctgcgccgtcattcccggtggggtgaactccccggtacgcgccttc
tcggcggtcggtggcaccccgctcttcatcaccgaagcgcgcggttgctggctaaccgac
gccgacggccgccgctatgtcgatctggtctgctcgtgggggccgatgatcctcggtcat
gcgcatcccgccgtggttgacgctgtcgctaccgttgctgcctccgggctgtcgttcggg
gcaccgactccggcggagacgcagctggccgccgagatcatcgggcggatggcgcccgtc
gagcgaatacggctggtgaactctggcactgaagccaccatgagcgcggtccggttggcc
cgtggattcaccggacggaccaagatcataaagttctctggctgctatcacggccatgtg
gacgcgctattagccgacgcgggctctggggtggcgacgctgagcctaccgtcctcgccg
ggagtgactggagccgccgcagctgacacaattgtgttgccctacaatgacatcgaggcc
gttcggcagacgtttgcccggttgggggaccagatcgccgcggtgattaccgaagcgagt
cccggcaatatgggagttgtcccacccgcgcccggctacaacgcggcgctgcgcgcgatc
accgcagagcatggtgcgctactgatcatcgacgaggtgatgaccggtttccgggtcagc
cgaagtggttggtacgggctcgatccggtcgccgctgacttgttcatcttcgggaaggtg
atgagcggcggaatgccggccgctgcgttcggcgggcgagctgaggtgatggagaggctg
gcgccgttggggccggtgtatcaggcggggactctgtcgggtaacccggtggcgatggcc
gccgggctggcaacgctacgggctgccgccgacgcagtttatgctacactggaccgcaac
gccgaccggttggttgcaatgctgtctgaggcgcttacggatgccggtgttccacatcag
attccgcgtgccggcaatatgttcagcgtgttcttttccgaagcgcctgtgaccgacttt
gcgtccgcttgcaacagccaggtctggcgttatccggcgttttttcatgccttgctggac
gcgggcgtctacccgccgtgcagtacgttcgaggcgtggtttgtctcggccgctctcgac
gacgccgcgttcggtcgcatcgttgatgctctgcccggtgcggccgctgccgcagtcgcc
gcccggcatcgggagtcctga
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