Mandrillus leucophaeus (drill): 105533183 Help Entry 105533183         CDS       T08763                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu00230   Purine metabolism mleu01100   Metabolic pathways mleu01522   Endocrine resistance mleu04015   Rap1 signaling pathway mleu04022   cGMP-PKG signaling pathway mleu04024   cAMP signaling pathway mleu04062   Chemokine signaling pathway mleu04072   Phospholipase D signaling pathway mleu04114   Oocyte meiosis mleu04211   Longevity regulating pathway mleu04213   Longevity regulating pathway - multiple species mleu04261   Adrenergic signaling in cardiomyocytes mleu04270   Vascular smooth muscle contraction mleu04371   Apelin signaling pathway mleu04540   Gap junction mleu04611   Platelet activation mleu04713   Circadian entrainment mleu04714   Thermogenesis mleu04723   Retrograde endocannabinoid signaling mleu04724   Glutamatergic synapse mleu04725   Cholinergic synapse mleu04726   Serotonergic synapse mleu04727   GABAergic synapse mleu04728   Dopaminergic synapse mleu04750   Inflammatory mediator regulation of TRP channels mleu04911   Insulin secretion mleu04912   GnRH signaling pathway mleu04913   Ovarian steroidogenesis mleu04914   Progesterone-mediated oocyte maturation mleu04915   Estrogen signaling pathway mleu04916   Melanogenesis mleu04918   Thyroid hormone synthesis mleu04921   Oxytocin signaling pathway mleu04923   Regulation of lipolysis in adipocytes mleu04924   Renin secretion mleu04925   Aldosterone synthesis and secretion mleu04926   Relaxin signaling pathway mleu04927   Cortisol synthesis and secretion mleu04928   Parathyroid hormone synthesis, secretion and action mleu04934   Cushing syndrome mleu04935   Growth hormone synthesis, secretion and action mleu04970   Salivary secretion mleu04971   Gastric acid secretion mleu04972   Pancreatic secretion mleu04976   Bile secretion mleu05012   Parkinson disease mleu05030   Cocaine addiction mleu05031   Amphetamine addiction mleu05032   Morphine addiction mleu05034   Alcoholism mleu05163   Human cytomegalovirus infection mleu05166   Human T-cell leukemia virus 1 infection mleu05200   Pathways in cancer mleu05207   Chemical carcinogenesis - receptor activation mleu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mleu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105533183 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105533183 (ADCY5)    04371 Apelin signaling pathway     105533183 (ADCY5)    04072 Phospholipase D signaling pathway     105533183 (ADCY5)    04024 cAMP signaling pathway     105533183 (ADCY5)    04022 cGMP-PKG signaling pathway     105533183 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105533183 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     105533183 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105533183 (ADCY5)    04062 Chemokine signaling pathway     105533183 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     105533183 (ADCY5)    04923 Regulation of lipolysis in adipocytes     105533183 (ADCY5)    04912 GnRH signaling pathway     105533183 (ADCY5)    04913 Ovarian steroidogenesis     105533183 (ADCY5)    04915 Estrogen signaling pathway     105533183 (ADCY5)    04914 Progesterone-mediated oocyte maturation     105533183 (ADCY5)    04921 Oxytocin signaling pathway     105533183 (ADCY5)    04926 Relaxin signaling pathway     105533183 (ADCY5)    04935 Growth hormone synthesis, secretion and action     105533183 (ADCY5)    04918 Thyroid hormone synthesis     105533183 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     105533183 (ADCY5)    04916 Melanogenesis     105533183 (ADCY5)    04924 Renin secretion     105533183 (ADCY5)    04925 Aldosterone synthesis and secretion     105533183 (ADCY5)    04927 Cortisol synthesis and secretion     105533183 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105533183 (ADCY5)    04270 Vascular smooth muscle contraction     105533183 (ADCY5)   09154 Digestive system    04970 Salivary secretion     105533183 (ADCY5)    04971 Gastric acid secretion     105533183 (ADCY5)    04972 Pancreatic secretion     105533183 (ADCY5)    04976 Bile secretion     105533183 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     105533183 (ADCY5)    04727 GABAergic synapse     105533183 (ADCY5)    04725 Cholinergic synapse     105533183 (ADCY5)    04728 Dopaminergic synapse     105533183 (ADCY5)    04726 Serotonergic synapse     105533183 (ADCY5)    04723 Retrograde endocannabinoid signaling     105533183 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105533183 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     105533183 (ADCY5)    04213 Longevity regulating pathway - multiple species     105533183 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     105533183 (ADCY5)    04714 Thermogenesis     105533183 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105533183 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     105533183 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105533183 (ADCY5)    05163 Human cytomegalovirus infection     105533183 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     105533183 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     105533183 (ADCY5)    05031 Amphetamine addiction     105533183 (ADCY5)    05032 Morphine addiction     105533183 (ADCY5)    05034 Alcoholism     105533183 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105533183 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105533183 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105533183 (ADCY5) Enzymes [BR:mleu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105533183 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC HILPDA Motif Other DBs NCBI-GeneID:  105533183 NCBI-ProteinID:  XP_011826944 Ensembl:  ENSMLEG00000036703 LinkDB All DBs Position Unknown AA seq 1018 aa AA seqDB search MLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGLACY ALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSALHLV IALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQR ENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLAS QCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMD MIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGR IHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMNRQR TNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFLGRA IDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQITIV PHSVFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVFTIT LVFLAAFVNMFTCNCKDLLGCLAQEHNISASQVNACHVMESAVNYSLGDEQGFCGSPWPN CNFPEYFTYSVLLSLLACSVFLQINCIGKLALMLAIELIYVLIVEVPGVTLFDNADLLVT ANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKLQAT EEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF YVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKV GKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTV NVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3057 nt NT seq  +upstreamnt  +downstreamnt atgctcatggccgtgctggtgctcgtgtgcctggtcatgttggccttccacgcggcgcgg cccccgctccagctgccctacctggccgtgctggcggccgccgtgggcgtcatcctcatc atggctgtgctctgcaaccgcgccgccttccaccaggaccacatgggcctggcctgctat gcgctcatcgccgtggtgctggccgtccaggtggtgggcctgctgttgccgcagccgcgc agcgcctctgagggcatctggtggaccgtgttcttcatctacaccatttacacgctgctg cccgtgcgcatgcgggccgcggtgctcagcggggtgctcctgtccgccctccacctggtc atcgccctgcgcaccaacgcccaggaccagttcttgctcaagcagcttgtctccaatgtt ctcattttctcctgcaccaacatcgtgggtgtctgcacccactacccagctgaggtctcc cagagacaggctttccaggagacccgagagtgcatccaggcgcggctccactcacagcgg gagaaccagcagcaggagcggctcctgctgtctgtccttccccgtcatgttgccatggag atgaaagcagacatcaacgccaagcaggaggatatgatgttccataagatttacatccag aaacatgacaacgtgagcatcctgtttgctgacatcgagggcttcaccagcctggcatcc cagtgcaccgcacaggaactggtcatgaccctcaacgagctcttcgcccgcttcgacaag ctggccgcagagaatcactgtttacgtattaagatcctcggggattgttattactgcgtc tcggggcttcctgaagcaagggctgaccacgcccactgctgcgtggagatgggcatggac atgatcgaggccatctcgttggtccgggaggtgacaggggtgaacgtgaacatgcgtgtg ggaattcacagcgggcgagtacactgcggtgtccttggtctaaggaagtggcagttcgac gtctggtctaacgacgtcacgctagccaaccacatggaggctggcggcaaggcgggacgc atccacatcaccaaggctacactcaactacctgaatggggactacgaggtggagccaggc tgtgggggcgagcgcaacgcctacctcaaggagcacagtatcgagaccttcctcatcctg cgctgcacccagaagcggaaagaagagaaggccatgatcgccaagatgaaccgccagaga accaactccatcgggcacaacccacctcactggggggctgagcgccccttctacaaccac ctgggtggcaaccaggtgtccaaggagatgaagcggatgggctttgaagaccccaaggac aagaatgcccaggagagtgcgaaccctgaggatgaagtggatgagtttctgggccgcgcc attgacgccaggagcattgacaggcttcggtctgagcacgtccgcaagttcctcctgacc ttcagggagcctgacttagagaagaagtactccaagcaggtagacgaccgatttggtgcc tatgtggcgtgtgcctcgctcgtcttcctcttcatctgctttgtccagatcaccatcgtg ccccactcagtattcatgctcagcttctacctgacctgttccctgctgctgaccttggtg gtgtttgtgtctgtgatctactcctgcgtaaagctcttcccctccccactgcagactctc tccaggaagatcgtgcggtccaagatgaacagcaccctggttggggtgttcaccatcacc ctggtgttcctggcggcttttgtcaacatgttcacgtgcaactgcaaggacctgctgggc tgcttggcacaggagcacaacatcagtgcaagccaggtcaacgcatgtcacgtgatggag tcggccgtcaactacagcctgggcgatgagcagggcttctgtggcagcccctggcccaac tgcaacttccccgagtacttcacctacagcgtgctgctcagcctgctggcctgctccgtg ttcctgcagatcaactgcatcgggaagctggcgctcatgctggccatcgagctcatctac gtgctcatcgtggaggtgccgggtgtcacgctcttcgacaatgccgacctgctggtcacc gccaatgccatagacttcttcaacaacgggacctcccagtgccctgagcacgcaaccaag gtggcattgaaggtggtgacgcccatcatcatctcagtctttgtgctggccctgtacctg cacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactgcaggccaca gaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctgcacaacatc ctgcccaaggatgtggccgctcacttcctggcccgcgagcggcgcaacgatgagctctac tatcagtcctgtgagtgcgtggcggtcatgttcgcctccatcgccaacttctccgagttc tacgttgagctggaggccaacaacgagggtgtcgagtgcctgcggctcctcaatgagatc atcgctgactttgatgagatcatcagcgaggatcggttccggcagctggagaagatcaag accatcggcagcacctacatggctgcctccggcctcaacgactccacctacgacaaggtg ggcaagacccacatcaaggcactggccgactttgccatgaagctgatggaccagatgaag tacatcaatgagcactctttcaacaacttccagatgaagatcgggctgaacattggcccc gtggtggccggggtgataggggcacgaaagcctcagtacgacatctggggcaataccgtg aacgtggccagccgcatggacagcactggtgtacctgaccgcatccaggtcaccacggac atgtaccaggtgctggccgccaacacgtaccaactggagtgccggggcgtggtcaaggtc aagggcaaaggcgagatgatgacctacttcctcaatggagggcccccgctcagttag

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