KEGG T08763: 105545287

Mandrillus leucophaeus (drill): 105545287

Entry

105545287         CDS       T08763

Symbol

LRP2

Name

(RefSeq) low-density lipoprotein receptor-related protein 2

K06233

low density lipoprotein-related protein 2

Organism

mleu Mandrillus leucophaeus (drill)

Pathway

mleu04340

Hedgehog signaling pathway

mleu04918

Thyroid hormone synthesis

mleu04979

Cholesterol metabolism

Brite

KEGG Orthology (KO) [BR:mleu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    105545287 (LRP2)
09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    105545287 (LRP2)
  09154 Digestive system
   04979 Cholesterol metabolism
    105545287 (LRP2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mleu04131]
    105545287 (LRP2)
Membrane trafficking [BR:mleu04131]
Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    105545287 (LRP2)

SSDB

Motif

Pfam:

Ldl_recept_a Ldl_recept_b FXa_inhibition cEGF DUF5050 EGF_CA SGL

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

Unknown

AA seq 4655 aa
MDRGPAAVACTLLLALVACLAPASGQECDSEHFRCGSGHCIPADWRCDGTKDCSDDTDEI
GCAVVTCQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDEHQGCSQSTCSSHQITCSNGQC
IPGEYRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCT
EICLHNEFSCGSGECIPHAYVCDHDSDCQDGSDEHACNYPTCGGYQFTCPSGRCIYQNWV
CDGEDDCKDNGDEDGCESSSHGVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENS
TTTGKYCSTTLCSALNCQYQCHETPYGGACFCPPGYTINHNDSRTCVEFDDCQIWGICDQ
KCESRPGHHLCHCEEGYILERGQHCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVES
QNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDIHGLNIQEVLNVSVETPENLAVDWVNNK
IYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLER
AFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSL
IPHPFGISLFEGQVFFTDWTKMAVLKANKFAETNPQVYYQASLRPYGVTVYHSLRQPYAT
NPCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIR
GIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKIDGTGREILAA
NRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKMRRTVVQYLNNPRSVVVHPFAGYL
FFTDWFRPAKIMRAWSDGSHLLPIVNTTLGWPNGLAIDWAASRLYWVDAYFDKIEHSTFD
GLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIAYILHL
KSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPNFQRVCGCPYGMRLASNHLTCEGDPTNE
PPTEQCGVFSFPCKNGRCVPSYYRCDGVNDCHDNSDEQLCGTLNNTCSSSAFTCGNGECI
PAHWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDE
KNCNSTEICQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGCVLNCTASQFKCASGDKC
ISVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGS
DEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCL
GYNICVNLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFL
LANDSKTCEDIDECDIPGSCSQHCYNMRGSFRCACDTGYMLESDGRTCKVTASENLLLLV
ASQNKIIADSVTSQVHNIYSLIENGSYIVAVDFDSISGRIFWSDATQGKTWSAFQNGTDR
RVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALD
PRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLD
YIDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVVM
YNIQWPLGIVAVHPSKQPNSVNPCAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNC
LRDDQPFLITVRQHIIFGISLNPDVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVENPGE
IHRVKTDGTNRTVFASVSMVGPSMNLALDWVSRNLYSTNPRTQSIEVLTLHGDIRYRKTL
IANDGTALGVGFPIGITVDPTRGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEH
LECVTLDIEEQKLYWAVTGRGVIERGNVDGTDRMILVHQLSHPWGIAVYDSFLYYTDEQY
EVIERVDKATGANKVVLRDNVPNLRGLRVYHRRNTAESSNGCSNNMNACQQICLPVPGGL
FSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALHV
DVDVSSGFVYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLY
FTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFL
DCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIHINGENSEVIRYGSRYPTP
YGITVFGNSIIWVDRNLKKIFQASKEPENTDPPTVIRDNINWLRDVTIFDKQVQPQSPAE
VNNNPCLENNGGCSHLCFALPGLYTPKCDCAFGTLESDGKNCAISTENFLIFALSNSLRS
LHLDPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYVSLSSGIHTPTV
IASGIGTADGIAFDWITRRIYYSDYLNQTINSMAEDGSNRTVIARVPKPRAIVLDPCQGY
LYWADWDMHAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQKIERSTL
TGMDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYRANKYDGSSQIAMTTNLLSQPRGI
NTVVKNQKEQCNNPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERC
GASSFTCSNGRCISKEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRC
DYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIPREFVCNGVDNCHDNNTSDEKNCPDR
TCQSGYTTCQNSNICIPRIYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCTSGRCIPQH
WYCDQEIDCFDASDEPASCGHPERTCLADEFKCDRGRCIPSEWICDGDNDCGDMSDEDER
HQCQNQNCSDSEFLCVNDRPPERRCIPQSWVCDGDVDCTDGYDENQNCTRRTCSENEFTC
GYGLCIPEIFRCDRHNDCGDYSDERGCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDG
SDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGCGVNECHDPSIS
GCDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTETPFVCSQKCENVIGSYICKCAP
GYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLGNVVALDFDRVEKR
LYWIDTQRQVIERMFLNKTNKETIINHRLPAAESLAVEWVSRKLYWLDARLDGLFVSDLN
GGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYIYWADWGHRAYIGRVGMDGTNKSVII
STKLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHRRHTVYDGTLPHPFAITIFEDTI
YWTDWNTRTVEKGNKYDGSNRQTLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGCSHLC
LIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCANNEKCIPIWWKCDGQKDCSD
GSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQ
CANKRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDC
GDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCH
PVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQCIPSRWICDH
YNDCGDNSDERDCEMRTCHPEYFQCTSGHCVPSELKCDGTADCLDASDEADCPTRFPDGA
YCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLNVPCNSPNRFRCDNNRCIYGH
EVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPNDNVCDDADDCGDWSDEL
GCNKGKERTCAENICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFGTCPQH
CRNTKGSYECVCADGFTSMSDHPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQD
EEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGHNNLVQEVDLKLKY
VMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMF
WTDWGKEPKIESAWMNGENRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYD
GTDRRVIAKEAMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQVRI
FHQLRYNKSVPNLCKQICSHLCLLRPGGYSCACPQGSSFIEGSTTECDAAIELPINLPPP
CRCMHGGNCYFDETDLPKCKCPSGYTGKYCEMAFSKGISPGTTAVAVLLTILLIVIIGAL
AIAGFFHYRRTGSLLPALPKLPSLSSLVKPSENGNGVTFRSGADLNMDIGVSGFGPETAI
DRSMAMSEDFVMEMGKQPIIFENPMYSVRDSAVKVVQPTQVTVSGNVDNKNYGSPINPSE
IVPETSPTSPAADGTQVTKWNLFKRKTKQTTNFENPIYAQMENEQKETVAATPPPSPSLP
AKPKPASRRDPTPTYSATEDTFKDTANLVKEDSEV

NT seq 13968 nt +upstreamnt +downstreamnt
atggatcgcgggccggcagcagtggcgtgcacgctgctcctggctctcgtcgcctgccta
gcgccggccagtggccaagaatgtgacagtgagcattttcgctgtggaagtgggcattgc
atccctgcagactggaggtgtgatgggaccaaagactgttcagatgacacggatgaaatt
ggttgtgctgttgtgacctgccagcagggctatttcaagtgccagagtgagggacaatgc
atccccaactcctgggtgtgtgaccaagatcaagactgtgatgatggctcagatgaacat
caaggttgctcacaaagtacatgctcaagtcatcagataacatgctccaacggtcagtgt
atcccaggtgaatacagatgcgaccacgtcagagactgcccagatggagctgacgagaat
gactgccaatacccaacatgtgagcagcttacttgtgacaatggagcctgctataacacc
agtcagaagtgtgattggaaagttgattgcagggactcctcggatgaaatcaactgcact
gagatatgcttgcacaatgagttctcatgtggcagtggagagtgtatccctcacgcttat
gtctgtgaccatgacagtgattgccaagacggcagtgatgaacatgcttgcaactatccg
acctgcggtggttaccagttcacttgccccagtggccgatgcatttatcaaaactgggtt
tgtgatggagaagatgactgtaaagataatggagatgaagatggatgtgaaagcagttct
catggtgttcataaatgttccccaagagaatggtcttgcccagagtcgggacgatgcatc
tccatttataaagtttgtgatgggattttagattgcccaggaagagaagatgaaaacagt
actactactggaaaatactgtagtacgactctgtgctctgccttgaactgccagtaccag
tgccatgagacgccttatggaggagcgtgtttttgtcccccaggttataccatcaaccac
aatgacagccgtacctgtgttgagtttgatgattgccagatttggggaatttgtgaccag
aagtgtgaaagccgacctggccatcacctgtgccactgtgaagaagggtatatcttggag
cgtggacagcattgcaaagctaatgattcctttggcgaggcctccattatcttctccaat
ggtcgggatttgttaattggtgatattcatggaaggagcttccggatcctagtggagtct
cagaatcgtggagtggccgtgggtgtggctttccactatcacctgcaaagagttttttgg
acagacactgtgcaaaataaggttttttcagttgacattcatggtttaaatatccaagag
gttctcaatgtttctgttgaaaccccagagaacctggctgtggactgggttaataataaa
atctatctggtggaaaccaaggtcaaccgcatagatatggtaaatttggatggaagctac
cgggttacccttataactgaaaacttggggcatcctagaggaattgccgtggacccaact
gttggttatttatttttctcagattgggagagcctttctggggaacctaagttggaaagg
gcattcatggatggcagcaaccgtaaagacttggtgaaaacaaagctgggatggcctgct
ggggtaactctggatatgatatcgaagcgtgtttactgggttgactctcggtttgattac
attgaaactgtaacttacgatggaattcaaaggaagactgtagttcatggaggctccctc
attcctcatccctttggaataagtttatttgaaggtcaggtattctttactgattggaca
aagatggccgtgctgaaggcaaacaagttcgcagagaccaacccacaagtgtactaccag
gcttccctgagaccctatggagtgactgtttaccattccctcagacagccctatgcgacc
aatccgtgtaaagataacaatgggggctgtgagcaggtctgtgtcctcagccacagaaca
gataatgatggtttgggcttccgttgcaagtgcacgtttggcttccagctggatacagat
gagcgccactgcattgctgttcagaatttcctcattttttcatcccaagttgctattcgt
gggatcccgttcaccttgtctacccaggaagatgtcatggttccagtttcggggaatcct
tctttctttgttgggattgattttgatgcccaggacagcactatctttttttcagatatg
tcaaaacacatgatttttaaacaaaagattgatggcacaggaagagaaattctcgcagct
aacagggtggaaaacgttgaaagtttggctttcgattggatttcgaagaatctctattgg
acagactctcattacaaaagtatcagtgtcatgaggctagctgataaaatgagacgcaca
gtagttcagtatttaaataacccccgatcagtggtagttcatccttttgctgggtatcta
ttcttcactgattggttccgtcccgctaaaattatgagagcatggagtgatggatctcat
ctcttgcctatagtaaacactactcttggatggcccaatggcttggccattgattgggct
gcttcacgattatactgggtagatgcctattttgataaaattgagcacagcacctttgat
ggtttagacagaagaagactgggccacatagagcagatgacacatccatttggacttgcc
atctttggagagcatttattttttactgactggagactgggtgccattatccgagtcagg
aaagcagatggtggagaaatgacagttatccgaagtggcattgcttacatactgcatttg
aaatcatatgatgtcaacatccagactggttctaacgcctgtaatcaacccacgcatcct
aacggtgactgcagccacttctgcttcccggtgccaaatttccagcgagtgtgtgggtgc
ccttatggaatgaggctggcttccaatcacttgacatgcgagggggacccaaccaatgaa
ccacccacggagcagtgtggcgtattctccttcccctgtaaaaatggcagatgtgtgccc
agttactatcgctgtgatggagtcaacgactgtcatgataacagtgatgagcaactatgt
ggcacacttaataatacctgttcatcttcggcgttcacctgtggcaatggggagtgcatt
cctgcacactggcgctgtgacaagcgcaacgactgtgtggatggcagtgatgagcacaac
tgccccacccacgcacctgcttcctgccttgacacccagtacacctgtgataatcaccag
tgtatctcaaagaactgggtctgtgacacagacaatgattgtggggatggatctgatgaa
aagaactgcaattcgacagagatatgccagcctagtcagtttaattgccccaaccatcga
tgtattgacttatcttttgtctgtgatggggacaaggattgtgttgatggatctgatgag
gttggctgtgtattaaactgtactgcttctcaattcaagtgtgccagtggggataaatgt
attagcgtcacgaatcgttgtgatggtgtttttgactgcagtgacaactcggatgaagca
ggctgtccaaccaggcctcctggtatgtgccactcagatgaatttcagtgccaagaagat
ggcatctgcatcccgaatttctgggagtgcgatgggcatccagactgcctctatggatct
gatgagcacaatgcctgtgtccccaagacttgcccttcatcatatttccactgtgacaat
ggaaactgcatccacagggcatggctctgtgatcgggacaatgactgcggggatatgagt
gatgagaaggactgccctactcagccctttcgctgtcctagttggcaatggcagtgtctt
ggctataacatctgtgtgaatctgagtgtagtgtgtgatggcatctttgactgccccaat
gggacagatgagtccccactttgcaacgggaacagctgctcagatttcaatggtggttgt
actcacgagtgtgttcaagagccctttggggcgaaatgcctatgtccattgggattctta
cttgccaatgattctaagacctgtgaagacatagatgaatgtgatattccaggctcttgc
agccagcactgttacaatatgagaggttctttccggtgcgcatgtgatacaggctacatg
ttagaaagtgatgggaggacttgcaaagttacagcatctgagaatctgctgttacttgtg
gcaagtcagaacaaaattattgccgacagtgtcacctcccaggtccacaatatctattca
ttgatcgagaatggttcttacattgtagctgttgattttgattcaattagtggtcgtatc
ttttggtctgatgcaactcagggtaaaacctggagtgcgtttcaaaatggaacggacaga
agagtagtatttgacagtagcatcatcctgactgaaactattgcaatagattgggtaggt
cgtaatctttactggacagactatgctctggaaacaattgaagtctccaaaattgatggg
agccacaggactgtgctgattagtaaaaacctaacaaatccaagaggactagcattagat
cccagaatgaatgagcatctattgttctggtctgactggggccaccaccctcgcatcgag
cgggctagcatggacggcagcatgcgcactgtcattgtccaggacaagatcttctggccc
tgcggcttaactattgactaccccaacagactgctctacttcatggactcctatcttgat
tacatagacttttgtgattataatggacaccatcggagacaggtgatagccagtgatttg
attatacggcatccctatgctctaactctctttgaagactctgtgtactggactgaccgt
gctactcgtcgggttatgcgagccaacaagtggcatggagggaatcagtcagttgtaatg
tataatattcaatggccccttgggattgttgcagttcatccttcgaaacaaccaaattct
gtgaatccatgtgccttttcccgctgcagccatctgtgcctgctttcctcacaggggccc
catttttactcctgtgtttgtccttcaggatggagtctgtctcctgatctcctgaattgc
ttgagagatgatcaacctttcttaataactgtaaggcaacatataatttttggaatctcc
cttaatcctgatgtgaagagcaatgatgctatggtccccatagcagggatacagaatggt
ttagatgttgaatttgatgacgctgagcaatacatctattgggttgaaaatccaggtgaa
attcacagagtgaagacagatggcaccaacaggacagtgtttgcttctgtatctatggtg
gggccttctatgaacctggccttagattgggtttcaagaaatctttattctaccaatcct
agaactcagtcaattgaggttttgacactccacggggatatcagatacagaaaaacactg
attgccaatgatgggacagctcttggagttggctttccgattggcataactgttgatcct
actcgtgggaagctgtactggtcagaccagggaactgacagtggggttcctgccaagatt
gccagtgctaacatggatggcacatctgtaaaaactctcttcactgggaaccttgaacac
ctggagtgtgtcacccttgacatcgaggagcagaaactctactgggcagtcactggaaga
ggagtgattgaaagaggaaacgtggatggaacagatcgaatgatcctggtacaccagctt
tcccacccttggggaattgcagtctatgattctttcctttattatactgatgaacagtat
gaggtcattgaaagagttgacaaggctactggggccaataaagtagtcttgagagataat
gttccaaatctgaggggtcttcgagtttatcacagacgcaatactgcggaatcctcaaat
ggctgtagcaacaacatgaatgcctgtcagcagatttgcctgcctgtaccaggaggattg
ttttcctgtgcctgtgccactggatttaaactcaatcctgataatcggtcctgctctcca
tataactctttcattgttgtttcaatgctgtctgcaatcaggggctttagcttggaattg
tcagatcattcagaaaccatggtgccagtggcaggccaaggacgaaatgcactgcatgtg
gatgtggatgtgtcctctggctttgtttattggtgtgattttagcagctcagtggcatct
gataatgcgatccgtagaattaaaccagatggatcttctttgatgaacattgttacacat
ggaataggagaaaatggagtccggggtattgcagtggattgggtagcaggaaatctttat
ttcaccaatgcctttgtttctgaaacactgatagaagttctgcggatcaatactacttac
cgccgtgttcttcttaaagtcacagtggacatgcctaggcatatcgttgtagatcccaag
aacagatacctcttctgggctgactatgggcagagaccaaagattgagcgttctttcctt
gactgtaccaatcgaactgtgcttgtgtctgagggcattgtcaccccacggggcttggca
gtggaccgaagcgatggctacgtttattgggttgatgattctttagatataattgcaagg
attcatatcaatggagagaactctgaggtgattcgttacggcagtcgttacccaactcct
tatggcatcactgtttttggaaattctatcatatgggtagataggaatttgaaaaaaatc
ttccaagccagcaaggaaccagagaacacagacccacccacagtgataagagacaatatc
aactggctaagagatgtgaccatctttgacaagcaagtccaaccccagtcaccagcagag
gtcaacaacaacccttgcttggaaaataatggtgggtgctctcatctctgctttgctctg
cctggattgtacaccccaaaatgtgactgtgcctttgggaccctagaaagtgatggcaag
aattgtgccatttcaacagaaaatttcctcatctttgctttgtctaattccttgagaagc
ttacacttggatcctgaaaaccatagcccacctttccaaacaataaatgtggaaagaact
gtcatgtctctagactatgacagtgtaagtgatagaatctacttcacacaaaatttagcc
tctggagttggacagatttcctatgtcagcctgtcttcagggatccatactccaactgtc
attgcttcaggtatagggactgctgatggcattgcctttgattggattactagaagaatt
tattacagtgactacctcaaccagacgattaattccatggctgaagatgggtctaaccgc
actgtgatagcccgcgttccaaaaccaagagcaattgtgttagatccctgccaagggtac
ctgtactgggctgattgggatatgcatgccaaaatcgagagagccacattgggaggaaac
ttccgggtacccattgtgaacagcagcctggtcatgcccagtgggctgactctggactat
gaggaggaccttctgtactgggtggacgctagtctgcagaagattgaacgcagcactctg
acgggcatggatcgtgaagtcattgtcaatgcagcagttcatgctttcggcttgactctc
tatggccagtatatttactggactgacttgtacacacaaagaatttaccgagctaacaaa
tatgatgggtcaagtcagattgcaatgaccacaaatttgctctcccagcccaggggaatc
aacactgttgtgaagaaccagaaagaacagtgtaacaatccttgtgaacagtttaatggg
ggctgcagccatatctgtgcaccaggtccaaacggtgctgagtgccagtgtccacatgag
ggcaactggtatttggccaataacaggaagcactgcattgtggacaatggtgaacgatgt
ggtgcatcttccttcacctgctccaatgggcgctgcatctcgaaagagtggaagtgtgat
aatgacaacgactgtggggacggcagtgatgagatggaaagtgtctgtgcacttcacacc
tgctcaccgacagccttcacctgtgccaatgggcgatgtgtccaatactcttaccgctgt
gattactacaatgactgtggtgatggcagtgatgaggcagggtgcctgttcagggactgc
aatgccaccacggagtttatgtgcaataatagaaggtgcatacctcgtgagtttgtctgc
aatggtgtagacaactgccatgataataacacttcagatgagaaaaattgccctgatcgc
acttgccagtctggatacacgacatgtcagaattcaaatatttgtattcctcgcatttat
ttgtgtgacggagacaatgactgtggagataacagtgatgaaaaccctacttattgcacc
actcacacgtgcagcagcagtgagttccaatgcacatctgggcgctgtattcctcaacat
tggtattgcgatcaggaaatagattgttttgatgcctctgatgaacctgcctcttgcggt
caccctgagcgaacctgcctcgccgatgagttcaagtgtgatcgagggaggtgcatccca
agcgaatggatctgtgatggtgataatgactgtggggatatgagtgatgaggatgaaagg
caccagtgtcagaatcaaaactgctcggattccgagttcctctgtgtaaatgacagacct
ccggagaggaggtgcattccccagtcttgggtctgtgatggcgatgtggattgtactgat
ggctacgatgagaatcagaattgcaccaggagaacttgctctgaaaatgaattcacctgt
ggttacggactgtgtatcccagagatattcaggtgtgaccggcacaatgactgtggtgac
tatagtgatgagaggggctgcttataccagacctgccagcagaatcagtttacctgtcag
aacgggcgctgcattagtaaaaccttcgtctgtgatgaggataatgactgtggagatgga
tctgatgagctgatgcacctgtgccacaccccagaacccacgtgtccgcctcatgagttc
aagtgtgacaatgggcgctgcattgagatgatgaaactctgcaaccacctggatgactgt
ttggacaacagcgatgagaaaggctgtggcgttaatgaatgccatgacccttcaatcagt
ggctgcgatcacaactgcacagacaccttaaccagtttctattgttcctgtcgtcctggt
tacaagcttatgtctgacaagcggacttgtgttgatattgatgaatgcacagagacgcct
tttgtctgtagccagaagtgtgagaatgtaataggctcctacatctgtaagtgtgcccca
ggctacctccgagaaccagatggaaagacctgccggcaaaacagtaacatcgaaccctat
ctcatttttagcaaccgttactatttgagaaatctaactatagatggctatttttactcc
ctcatcttggaaggactgggcaatgttgtggcattagattttgaccgagtagaaaagaga
ttgtactggattgatacacagaggcaagtcattgagagaatgtttctgaataagacaaac
aaggagacaatcataaaccacagactaccagctgcagaaagtctggctgtagagtgggtt
tccagaaagctctactggttggatgcccgcctggatggcctctttgtctctgacctcaat
ggtggacaccgccgcatgctggcccagcactgtgtggatgccaacaacaccttctgcttt
gataatcccagaggacttgcccttcaccctcaatatgggtacatctactgggcagactgg
ggtcaccgcgcatacattgggagagtaggcatggatggaaccaacaagtctgtgattatc
tccaccaagttagagtggcctaatggcatcaccattgattacaccaatgatctactctac
tgggcagatgcccacttgggttacatagagtactctgatttggagggccaccgtcgacac
acagtgtatgatgggacactgcctcacccctttgctattaccatttttgaagacactatt
tattggacagattggaatacaaggacagtggaaaagggaaacaaatacgatggatcaaat
agacagacactggtgaacacaacacacagaccatttgacatccatgtttaccatccatat
aggcagcccattgtgagcaatccctgtggtaccaacaatggtggctgttctcatctctgc
ctcatcaaaccaggaggaaaagggttcacttgcgagtgtccagatgacttccgcaccctt
cagctgagtggcagcacctactgcatgcccatgtgctccagcacccagttcttgtgcgct
aacaatgaaaagtgcattcctatctggtggaaatgtgatggacagaaagactgctcagat
ggctctgatgaactggccctttgcccgcagcgcttctgccgactaggacaattccagtgc
agtgacggcaactgcaccagcccacagactttatgcaatgctcaccaaaattgccctgat
gggtctgatgaagaccgtcttctttgtgagaatcaccactgtgactccaatgaatggcag
tgcgccaacaaacgttgcatcccagaatcctggcagtgtgacacgtttaacgactgtgag
gataactcagatgaagacagttcccactgtgccagcaggacctgccggccgggccagttt
cggtgtgctaatggccgttgcatcccgcaggcctggaagtgcgatgtggataatgattgt
ggagaccactcggatgagcctattgaagaatgcatgagctctgcccatctctgtgacaac
ttcacagaattcagctgcaaaacaaattaccgctgcatcccaaagtgggccgtgtgcaat
ggtgtagacgactgcagggacaacagtgatgagcaaggctgtgaggagaggacatgccat
cctgtgggggatttccgctgtaaaaatcaccactgcatccctcttcgttggcagtgtgat
gggcaaaatgactgtggagataactcagatgaggaaaactgtgcaccccgggagtgcacg
gagagcgagtttcgatgtgtcaatcagcagtgcattccctcacgatggatctgtgaccat
tacaacgactgtggggacaactcagatgaacgggactgtgagatgaggacctgccatcct
gaatattttcagtgtacaagtggacattgcgtacccagtgaattgaaatgtgatggaacc
gctgactgtttggatgcctctgatgaagctgattgtcctacacgctttcctgatggtgca
tactgccaggctactatgtttgaatgcaaaaaccatgtttgtatcccaccgtattggaaa
tgtgatggcgatgacgactgtggcgatggttcagatgaagaacttcacctgtgcttgaat
gttccctgtaattcaccaaaccgtttccggtgtgacaacaatcgttgcatttatggtcat
gaggtgtgcaacggtgtggatgactgtggagatggaactgatgagacagaggagcactgt
agaaaaccaacccctaaaccttgtacggaatatgaatataagtgtggcaatggacattgc
attccaaacgacaatgtgtgtgatgatgccgatgactgtggtgattggtctgatgaactg
ggttgcaataaaggaaaagaaagaacatgtgctgaaaatatatgcgagcaaaactgtacc
caattaaatgaaggaggatttatctgctcctgtacagctgggttcgaaaccaatgttttt
gacagaacctcctgtctagatatcaatgagtgtgagcaatttgggacttgtccccagcac
tgcagaaataccaaaggaagttatgagtgtgtctgtgctgatggcttcacgtctatgagt
gaccaccctgggaaacgatgtgccgctgagggtagctctcctttgttgctactgcctgac
aatgtccgaattcgaaaatataatctctcatctgagaggttctcagagtatcttcaagat
gaggaatatatccaagctgttgattatgactgggatcccgaggacataggcctcagtgtt
gtatattacaccgtgcgaggggagggctctaggtttggtgctatcaaacgtgcctacatc
cccaactttgaatccggccacaataatcttgtgcaggaagttgacctgaaactgaaatat
gtaatgcagccagatggaatagcagtggactgggttggaaggcatatttactggtcagat
gtcaagaataaacgcattgaggtggctaaacttgatggaaggtacagaaagtggctgatt
tccactgacctggatcaaccagctgcaattgctgtgaatcccaaactagggcttatgttc
tggactgactggggaaaggaacctaaaattgagtctgcctggatgaatggagagaaccgc
aacatcctggttttcgaggaccttggttggccaactggcctttctatcgattatttgaac
aatgaccgaatctactggagtgacttcaaggaggacgttattgaaaccataaaatacgat
ggaactgataggagagtcattgcaaaggaagcaatgaacccttacagcctggacatcttt
gaagaccagttatactggatatctaaggaaaagggagaagtatggaaacaaaataaattt
gggcaaggaaagaaagagaaaacgctggtagtgaacccttggctcactcaagttcgaatc
tttcatcaactcagatacaataagtcagtgcccaacctttgcaaacagatctgcagccac
ctctgccttctgagacctggaggatacagctgtgcctgtccccaaggctccagctttata
gaggggagtaccactgagtgtgatgcagccatcgaactgcctatcaacctgcctccccca
tgcaggtgcatgcacggaggaaattgctattttgatgagactgacctccccaaatgcaag
tgtcctagcggctacaccggaaaatattgtgaaatggcgttttccaaaggcatctctcca
ggaacaaccgcagtagctgtgctgttgacaatcctcttgatcgtcataattggagctctg
gcaattgccggattcttccactataggagaaccggctcccttttgcctgctctgcccaag
ctgccaagcttaagcagtcttgtcaagccctctgaaaatgggaatggggtgaccttcaga
tcaggggcagatcttaacatggatattggagtgtctggttttggacctgagactgctatt
gacaggtcaatggcaatgagtgaagactttgtcatggaaatggggaagcagcccataata
tttgaaaacccaatgtactcagtcagagacagtgctgtcaaagtggttcagccaacccag
gtgactgtatctgggaatgtggataataagaattatgggagtcccataaacccttctgag
atagttccagagacaagcccaacttccccagctgctgatggaactcaggtgacaaaatgg
aatctcttcaaacgaaaaactaaacaaactaccaactttgaaaatccaatctatgcacag
atggagaacgaacaaaaggaaactgttgctgcgaccccacctccatcaccttcgctccct
gctaagcctaagcctgcttcgagaagagacccaactccaacctattccgcaacagaagac
acttttaaagacactgcaaatcttgttaaagaagactctgaagtatag

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