KEGG   Mustela lutreola (European mink): 131812400
Entry
131812400         CDS       T09578                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk03420  Nucleotide excision repair
mlk04115  p53 signaling pathway
mlk04120  Ubiquitin mediated proteolysis
mlk05161  Hepatitis B
mlk05169  Epstein-Barr virus infection
mlk05200  Pathways in cancer
mlk05202  Transcriptional misregulation in cancer
mlk05210  Colorectal cancer
mlk05212  Pancreatic cancer
mlk05213  Endometrial cancer
mlk05214  Glioma
mlk05216  Thyroid cancer
mlk05217  Basal cell carcinoma
mlk05218  Melanoma
mlk05220  Chronic myeloid leukemia
mlk05222  Small cell lung cancer
mlk05223  Non-small cell lung cancer
mlk05224  Breast cancer
mlk05225  Hepatocellular carcinoma
mlk05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    131812400 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    131812400 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    131812400 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    131812400 (DDB2)
   05202 Transcriptional misregulation in cancer
    131812400 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    131812400 (DDB2)
   05212 Pancreatic cancer
    131812400 (DDB2)
   05225 Hepatocellular carcinoma
    131812400 (DDB2)
   05226 Gastric cancer
    131812400 (DDB2)
   05214 Glioma
    131812400 (DDB2)
   05216 Thyroid cancer
    131812400 (DDB2)
   05220 Chronic myeloid leukemia
    131812400 (DDB2)
   05217 Basal cell carcinoma
    131812400 (DDB2)
   05218 Melanoma
    131812400 (DDB2)
   05213 Endometrial cancer
    131812400 (DDB2)
   05224 Breast cancer
    131812400 (DDB2)
   05222 Small cell lung cancer
    131812400 (DDB2)
   05223 Non-small cell lung cancer
    131812400 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    131812400 (DDB2)
   05169 Epstein-Barr virus infection
    131812400 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mlk04121]
    131812400 (DDB2)
   03400 DNA repair and recombination proteins [BR:mlk03400]
    131812400 (DDB2)
Ubiquitin system [BR:mlk04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     131812400 (DDB2)
DNA repair and recombination proteins [BR:mlk03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      131812400 (DDB2)
SSDB
Motif
Pfam: WD40 NBCH_WD40 EF-hand_1 EF-hand_6
Other DBs
NCBI-GeneID: 131812400
NCBI-ProteinID: XP_058997859
LinkDB
Position
1:272620357..272643716
AA seq 426 aa
MAPRKRPETQKTPEVAVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPPSSIVRALHHHKLGNAVWPSLQQGLQQAFLHSLASYRIFQKAAPFDRRATSLTWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGTT
RLQDFKGNTVRVFASSDTCNVWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDGA
QLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKATWHPRYNLVVVGRYPDPNF
KSCTPHELRTIDVFDGNSGKMMFQLYDPESSGIISLNEFNPMGDTLASVMGYHILIWSQE
EAGMRT
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcctaggaagcgcccagaaacccagaagacccccgaggtggctgtgcgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccctggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctg
caggtcccgccaccaagcagcatcgtcagggccctccaccaccataagctaggcaacgcc
gtctggccatcactgcagcagggtctccagcaggcctttctgcactctctggcttcttac
cggatattccaaaaggctgccccctttgacaggagggccacatccttgacatggcaccca
actcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaacttt
ggcataaaggacaaacctaccttcattaaagggattggagctggagggagcatcactggg
ctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacactgtccgagtttttgccagctcagacacctgcaac
gtctggttttgcagcctggatgtgtctgccagaagcagaatggtggtcacgggagacaat
gtggggcacgtgatcctgctgaacatggacggcagggagctttggaatctgagaatgcac
aaaaagaaagtgacccacgtggccctgaatccatgctgtgattggttcctggccacagcc
tccgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccactcactgccgcatagccatcctgtcaacgcagcttgtttcagtcctgatggagcc
cagctcctgactactgaccagaagagtgagctccgggtttactcagcctcccagtgggac
tgccccccaagcctgatcccacaccctcaccgccacttccagcacctgacgcccatcaag
gcaacctggcatcctcggtacaacctcgttgtcgtgggccgatacccagatcctaatttc
aaaagctgtaccccccacgaattaaggacaatcgatgtgtttgatggaaactcagggaag
atgatgtttcagctctatgacccagaatcttctggtatcatttcgctcaatgagttcaat
cccatgggggacacgttggcctctgtgatgggttatcacattctcatttggagccaggag
gaagctgggatgcggacatga

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