Megasphaera massiliensis: LCQ47_08225
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Entry
LCQ47_08225 CDS
T07781
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
mmax
Megasphaera massiliensis
Pathway
mmax00230
Purine metabolism
mmax01100
Metabolic pathways
mmax01110
Biosynthesis of secondary metabolites
Module
mmax_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mmax00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
LCQ47_08225
Enzymes [BR:
mmax01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
LCQ47_08225
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
AIRS
DUF5645
Motif
Other DBs
NCBI-ProteinID:
UBS52889
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Position
1768473..1772216
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AA seq
1247 aa
AA seq
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MQSIRRLYVAKKGIFADEAKRLLTDLQENLLIKGLTDIHIFHRYDVSGLDDAAFEAAKNM
IFSEPPVDAVYDTLPTKEGDTVLAVEYLPGQYDQRADSAVQCLQMLTMKNDSLVRTAQVI
VLSGSLSAEDIDAVKHYCINPVEAREASLEPAESLELAWEKPADVPTVEGFIFMDDAALT
DLSAQMGLAMSFDDLKFVQTYFRDEEKRNPTITEIRVIDTYWSDHCRHTTFMTELTDVSF
EKGTFTAPIQRAYESYKTTRENLNRKKPQTLMDMATIAVKELKAAGKLDNLDESEEINAC
TIIIPVDVDGVEEEWLLLFKNETHNHPTEIEPFGGAATCLGGCIRDPLSGRSYVYQAMRV
TGAGDPRQAVQDTLVGKLPQRKLTTGAAKGYSSYGNQIGLATGEVKEYYNPGFVAKRMEI
GAVLGAAPRKNVVREEPLPGDIIILLGGKTGRDGCGGATGSSKKHTVESLETCGAEVQKG
NALTERKIQRMFRRQEVTTLIKRCNDFGAGGVSVAIGELTDGLDINLDKVPKKYEGLDGT
ELAISESQERMAVVVAPENVDKFMKYAAEENLEATIVAVATDTKRLVMHWRNQNVVNITR
AFLDTNGVTQRRKALVTAPEDKDFFKAPDVKDVAKTWLDTMGTLNIASEQGLAERFDSTI
GARTVLMPFGGKYQKTPVEGMVAKIPVEHGNTTTASIFTHGYDPDLAIWSPFHGALYAVI
QSIAKLVALGGDRKKVYLTMQEFFQSLGKNETAWGQPVSALLGAFVAQQVMEVAAIGGKD
SMSGTFEHLTVPPTLVSFAIAPEHTDHIVSPEFKASDDAVLLFDLPRNGEGMPDFDTFKQ
HCDFLHQAVIDGKVKAMHAVGQGGIAAAVAQMAFGNRIGFDVDADFAVQELFNLRYGALL
VETDSATAAAWSKRDQVSLVGKTTTSANITVDGVTIALSDLQEAWEKPLNQIFPIKDKDG
QGDAELPLFTTYGPRRSEAFGAPHVFIPVCPGTNCEYDSAAAFERAGATTDVMVLRNNTP
QDLAESIEEMAKRMAKAQIIMFPGGFSAGDEPEGSGKFIATLFRNPALSEALESLLYQRD
GLALGICNGFQALIKLGLLPYGQIQPLKADSPTLTYNSIGRHLSRMVDTKVVSVMSPWFS
SCKAGDIHTVAISHGEGRFIATPEQIRELAAKGQIATQYVDLSGKASYESEYNPNQSVLA
VEGITSPDGRVLGKMAHTERFSADDVFKNIDGNKLQPIFTSGVNYFK
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
atgcagtctattcgacgtttgtatgttgccaagaaaggtatttttgctgatgaggcaaag
cgattactcactgatttacaggaaaacctgttgataaaagggttaactgatattcacatt
ttccaccgctacgacgtatccggtctcgatgatgcggctttcgaagcggctaaaaatatg
attttctcggaaccgcctgtcgatgccgtttacgatacactgcctacgaaggaaggcgat
acggtcctggccgtcgaatacctgcccggtcaatatgaccagcgtgccgattcagctgtt
cagtgcctgcagatgctgaccatgaaaaatgacagcctggttcggacggcacaggtcatc
gtcctgtccggcagcttatcggctgaagatatcgatgctgtcaagcactactgcatcaac
cccgtcgaagctcgtgaagcttcgttggaaccggctgaatcgttggaattggcttgggaa
aaaccggctgacgtccctactgtcgaaggctttatcttcatggatgatgcggccttgacc
gacctttcggcgcagatgggcctggctatgagcttcgacgatttgaagttcgtccagacg
tacttccgcgacgaagaaaaacggaatccgacgattaccgaaatccgagtcatcgatacg
tactggtcagaccactgccgtcatacgacgttcatgactgaactgacggacgtttctttt
gaaaaaggaacctttacggctcctatacagcgggcttatgaatcgtataagacgacgcgg
gaaaacctgaaccgcaagaaacctcaaaccctcatggatatggcaaccatcgccgtcaag
gaattgaaagctgccggaaaactcgataatctcgacgaatcggaagaaatcaacgcctgc
acgatcattattcccgtcgatgtcgatggcgtcgaagaagaatggctgctcttatttaaa
aacgaaacccataaccacccgactgaaatcgaaccgttcggcggcgctgcgacctgcctt
ggcggttgtattcgcgaccccttgagcggccgttcctacgtctatcaggccatgcgcgta
accggtgccggcgatcctcgtcaggctgtccaggatactttggtcggcaaactgccgcag
cgcaagctgacgaccggtgccgccaagggatacagttcgtatggcaatcagatcggcctg
gctacgggtgaagtcaaggaatactacaacccgggattcgtcgccaaacgtatggaaatc
ggtgccgttctcggtgcggctccgcggaagaacgtcgttcgcgaagaaccccttcccggc
gatatcatcatcctcctcggaggcaagaccggccgtgacggctgcggcggcgctacgggt
tcttccaagaaacataccgttgaatcattggaaacctgcggtgctgaagtccaaaaaggg
aacgccctgactgaacgaaagattcagcgcatgttccgccgccaggaagtcacgacgctt
attaagcgctgcaatgactttggtgccggcggtgtttccgtcgctatcggcgaattgacg
gacggccttgacatcaatctcgataaagttcccaaaaaatacgaaggcctcgacggaacg
gaattggctatttctgaatctcaggaacgaatggccgtcgtcgtggctccggaaaatgtc
gataaattcatgaaatatgctgctgaagaaaatctggaagcgacgattgtcgccgtggct
accgatacgaaacggctggtcatgcactggcgcaatcagaacgtcgtcaatattactcgg
gctttcctcgataccaacggcgttactcagcggcgcaaggctttggtcacggcaccggaa
gataaggatttcttcaaggcaccggatgtaaaagacgtcgctaagacatggctcgatacg
atgggaaccttgaacatcgcttcggaacaaggcttggccgaacgctttgacagcactatc
ggggctcgcacggtcctcatgcctttcggcggtaaatatcagaagacgccggtcgaaggg
atggtcgctaagattcccgtagaacacgggaatacgacgacggccagcattttcacccac
ggctacgatccggacctcgctatttggagtcccttccacggcgctctctatgccgtcatc
cagtccattgcgaaactcgttgccctcggcggcgaccgtaagaaagtataccttacgatg
caggaattcttccagagcttgggcaaaaatgaaaccgcctggggccagccggtcagcgcc
ctcctcggtgccttcgtcgctcagcaggtcatggaagtcgccgccatcggcggtaaggac
agcatgagcggtacctttgaacacctgacggttccgccgactttggtttctttcgccatt
gcaccggaacataccgatcatatcgtatcgccggaatttaaggcttctgacgatgccgtc
ctcctcttcgatttgccgcgtaacggcgaagggatgccggacttcgatacctttaaacag
cattgtgacttcctccatcaagccgtcatcgacggtaaggtcaaagccatgcacgccgtc
ggtcagggcggtatcgcagctgctgtggctcagatggcctttggcaaccgaatcggtttt
gacgtcgatgcagactttgctgtacaggaactgtttaacctccgttacggcgccctctta
gttgaaaccgacagtgcgacggctgccgcatggagtaaacgcgatcaggtcagcttggtc
ggtaagacgaccacgtcggcaaatatcacggtcgacggcgtaacgattgccttgagtgac
cttcaggaagcttgggaaaaaccgctgaatcagattttcccgattaaggataaggatggc
caaggcgacgccgaactgcccttgtttacgacctatggtcctcgccgcagtgaagccttt
ggcgctccgcatgtctttattcccgtttgcccgggaacgaactgcgaatacgactcggca
gctgcctttgaacgggccggcgcaacgacagatgtcatggtccttcgcaataacacgccg
caggacctggccgaatcgattgaagaaatggcaaaacgcatggccaaagcacagatcatc
atgttccccggcggcttcagtgccggtgacgaaccggaaggttcgggcaagttcattgcc
accttgttccggaatccggccctgtccgaagccctcgaaagtctcttgtatcagcgcgat
ggcttagcccttggcatctgcaacggcttccaggctctgattaaactcggccttttgccc
tatggccagattcagcctttgaaggccgacagcccgaccttgacgtacaactccatcggc
cgtcacctttcccgcatggtcgacaccaaagtcgtttcggtcatgagcccttggttcagc
agctgtaaagccggcgatattcacaccgtcgctatttcccatggggaaggccgctttatt
gcgacgccggaacagattcgtgaactcgccgccaaaggccagattgcaacgcagtacgtc
gacctttccggcaaagcttcttatgaaagcgaatacaacccgaatcagtcggtcctggcc
gtggaaggcattaccagtcctgacggtcgtgtcctcggcaagatggctcatacggaacgg
ttcagcgccgacgatgtctttaaaaacattgacggcaataagctccaacccatcttcaca
tccggcgtaaactactttaaataa
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