Mycolicibacterium monacense: EWR22_03565
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Entry
EWR22_03565 CDS
T08739
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mmon
Mycolicibacterium monacense
Pathway
mmon00860
Porphyrin metabolism
mmon01100
Metabolic pathways
mmon01110
Biosynthesis of secondary metabolites
mmon01120
Microbial metabolism in diverse environments
mmon01240
Biosynthesis of cofactors
Module
mmon_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mmon_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mmon00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
EWR22_03565
Enzymes [BR:
mmon01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
EWR22_03565
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
EWR22_03565
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
QHP84520
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Position
759702..761366
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AA seq
554 aa
AA seq
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MTRQESGRGRKMKPGRITFVGSGPGDPGLLTARAHSVLVNAALVFTDPDVPEAVLSLVGA
HLPPPSGPEPAEPADAADEQAGSTIPGGPDIRPALGDPAEVAKVLAGEAKHGVDVVRLVA
GDPLSVDAVIAEVNALAKSHANFEIVPGLPNTTAVPTYAGLPLGSTHTVADVRDPNVDWA
ALAAAPGPLILHATASHLPDAARTLIEYGLAETTPAVVTANGTTCQQRSVESTLSGLLDK
AALTAPDATGAPAAPLAGPLVVTLGRTVTNRARLNWWESRALYGWTVLVPRTKDQAGEMS
DKLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFNEF
GLDARAFSGVKIACVGQATAERVRAFGINPELVPTGEQSSLGLLDEFPPYDDIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPASTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPEVAAVGPLVEALAEHAARLRA
EGALPPPRKKSRRR
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgactcggcaggagagcgggcgtgggcgcaagatgaagcccggccgcatcaccttcgtg
ggctcgggcccgggcgaccccggcctgttgaccgcacgggcccacagtgtgctcgtcaat
gccgcgctggtcttcaccgaccccgacgtccccgaggcggtgctgtccctggtgggcgcg
cacctgcccccaccgtcgggccctgaaccggccgagccggcggacgccgccgacgagcag
gcgggctcgaccatccccggcggcccggacatccggcccgcgctgggcgatccggccgag
gtggccaaggtcctggccggtgaggccaagcacggtgtggacgtggtccggctggtggcc
ggcgacccgctgtcggtcgacgccgtcatcgccgaggtgaacgcgctggccaagagccac
gccaacttcgagatcgtgcccggcctgccgaacaccaccgcggtcccgacgtacgccggc
ctgccgctgggttccacccacaccgtcgccgacgtgcgcgacccgaacgtggactgggcg
gccctggccgccgcgcccggcccgctgatcctgcacgcgaccgcctcgcatctgcccgac
gccgcgcgcacgctgatcgagtacggcctggccgagaccaccccggcggtggtcaccgcc
aacggcaccacctgccagcagcgctcggtcgagtcgacgctgtccgggctgctcgacaag
gccgcgctgaccgcaccggacgcgaccggtgcacccgccgcaccgctggccggcccgctg
gtcgtgacgctcggccgcaccgtcaccaaccgggcccgcctgaactggtgggagagccgc
gcactgtacggctggaccgtgctggtgccgcggaccaaggatcaggccggggagatgagc
gacaagctcgtcggccacggcgccctgccgatcgaggtgcccaccatcgccgtcgaaccg
ccgcgcagccccgcgcagatggagcgtgcggtcaagggtctggtcgacggccggttccag
tgggtcgtgttcacctccaccaacgcggtgcgcgcggtgtgggagaagttcaacgagttc
gggctcgacgcccgcgcgttctccggtgtgaagatcgcctgcgtcggtcaggcgacggca
gagcgggtgcgcgcgttcgggatcaaccccgagctggttccgacgggggagcagtcctcg
ctgggtctgctcgacgagttcccgccgtacgacgacattttcgatccggtgaaccgggtg
ctgctgccgcgcgccgacatcgccaccgagacgctggccgaggggctgcgcgaacgcggt
tgggagatcgaggacgtcaccgcctaccggacggtgcgtgccgcaccgccgccggcctcg
acgcgcgagatgatcaagacgggcggcttcgacgcggtgtgcttcacgtcgagctcgacg
gtgcgcaacctggtcggcatcgccggtaagccgcacgcccgcacgatcgtcgcctgcatc
gggcccaagaccgcggagacggcagcggagttcggcctgcgcgtcgacgtgcagcccgag
gtggccgcggtcggtccgctggtggaggcgctcgccgagcacgccgcccgactgcgcgcc
gagggtgcgctgccgccgccgcgcaagaagagtcgccgccgctga
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