Mustela nigripes (black-footed ferret): 132015987 Help Entry 132015987         CDS       T09425                                  Symbol PCLO Name (RefSeq) protein piccolo   KO K16882   protein piccolo Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp04911   Insulin secretion Brite KEGG Orthology (KO) [BR:mnp00001]  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     132015987 (PCLO)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mnp04131]     132015987 (PCLO) Membrane trafficking [BR:mnp04131]  Exocytosis   Calcium ion-dependent exocytosis    Others     132015987 (PCLO) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-piccolo C2 PDZ FYVE_2 Motif Other DBs NCBI-GeneID:  132015987 NCBI-ProteinID:  XP_059252928 LinkDB All DBs Position 4:79472851..79881815 Genome browser AA seq 5182 aa AA seqDB search MGNEASLEGEGLPEGLAAAAAAAAAGGGAGGAGSSLHTVIPAGMEADLSQLSEEERRQIA AVMSRAQGLPKGSVPPAAAEPPSMHRKQELDSSHPPKQPGKPPDPGRSAQPGLSKSRTTD TLRSEQKSPGRSPSTISLKESKSRTDLKEEHKTSMMPGFLSEVNPLSAVSSVVNKLNPFD LISDSDASQEETAKKQKVAQKEQGKPEGITKPPSQPSPKPGPKQQGPVRVPPQQDGSPKS VSSQQPEKMKSQPPGTGKPIQGLTQSPQTDQAQWPLQRDAARPQTKQSDAVRGESVKPAL QSPSKQPIQQASPGKPAAQQPGPEKVATPHPGPAKPSAQQPGTAKPAVQQPGPKSSAQPL GPVKTQVQQAGGEKLPSQQPGPAKPPAQQPGTPKSPAQLPGPAKTPSQPVGPTKSLAQQP SLAKPPPQQPSPAKPPPQQPGPAKPPPQQPGPAKPPPQQPGLAKPPPQQPGPAKPPPQQP GPAKPPPQQPGPAKPPPQQPGLAKPSPQQPGPAKPPPQQPGPAKPPPQQPGPAKPPPQQP GLAKPPPQQPGPAKPPPQQPGPAKPPPQQPGPAKPSLQQPGPVKPPQQPGPAKASAQQSS KPVSQTGAGKPLQPPASPSAAQTPVQGLSKTICPLCNTTELLLHVPEKANFNTCTECQTT VCSLCGFNPNPHLTEIKEWLCLNCQMKRALGGDLAPVPLSPQPKPKTAPVTPPSAVSKPS PQPQQTSPKKDTVPKQDLSKAPEAKKPPPLVKQPTIHGSPPVAAKQPPVAESSSKPTPPK EPSVPSEQAKVPMAEDKPKQPKTVKPATDVSSAPTAAKPDTPSSKVQLEDQQITAPPPKT DAAKPSQSFPPTGEKVTPIDSKVIPRPASDSKILSHPGPSSETKGQKQVDSVQKREEPKK AQTKMSPKPDAKPMPKGSPPAPGPQPTTGQTAPPSQQPPKPQEQSRRFSLNLGSITDAPR SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGSQSQSGPGAPTKQGPPPPQPPHQG PPKATGQGSPAPAKVIPVKKETKAPVAEKLEPKAEQVPTVKRAETEKKPPLVKDSKPSAA EPQTPVLTPKVEKTPKPESTCPLCKTELNVGSKEPPNFNTCTGCKNQVCNLCGFNPTPHL TEIQEWLCLNCQTQRAISGQLGDMGKMPSTPSGPKASPTPVPPEQPSQKTTMPPQAKMKK KEQEVKTEAEQILPEKVKEIPSVEKILPKVTTDHKQESQLEKDKTSAPQEEKPPSEDKKS LPEEKKPPPEEKKPTSEEKKPAPEDKKLPPVTKPSALEEEQKQDLFKTQVPTTEEKPEGI VTPQVVQETPPQTKMEDKPCGPPPSLPKEDDEATQTMKEQPQAAGTAKPDRVEPGKEKTE KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPSDEKDLLKGLKKDSFSQE SSPSSPSDLAKLESTVLSILEAQASTLVEEKTEKKTQPPEVTCEPPKDQPKTQSLSETLE TTVAEEELTKSQEEKDMLKKDSQQDGPSRKDREEKSEFVDDTATRRQSYDSVEDSSESEN SPLPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRSQ LKEISSSLESQKKEETKGKGKATPGKHRRLTRKSSTSFDDDAGRRHSWHDEDDETFDESP ELKYRETKSQESEELVIAGGGGLRRFKTIELNSTIADKYSAESSQKKTTLYFDEEPELEM ESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR SHGPLLPTIEDSSEEEELREEEELLKEQEKQRELEQQQRKTSSKKSKKDKDELRAQRRRE RPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQ KVYKLPTAVSLFSPTDEQSIMQKEGGQKALKSAEEMYEEMMHKTHKYKAFPGATERDEIF EKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEDENGFMQQRGKDQKTRIPEQIYE DPMQKITDLQKEFYQLESLHSVVPQEDIVSSSFIIPESHEIVDLGSMVTSTSEEKKLLDA DAAYEELMKRQQMQLTPGSSPTQPPITDDMTESTMDFDRVPDASLTSSVLSGASLTDSTS SATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDT PSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDIVTKLEDSEISSSTYFPGSIIDYPEE ISVSLDRTAVPDGRTSADHVVISLSDMEPPIIESVGTVPEGLIADTVSTDSSTSEKDPGK KDKRDTGNGIILEVLEAYRDKREKSEVELTKMGLSETVFDHPPSSAGAVEEQVLATCFLS GQVFDQAKPASPLPSGSPSVTSLPKKTHPFFRSSSLDASAQPPPPPPPPPPPPPPPPPPP PPPLPPPTSPKPPVHPKKKLTVTAPVTLTPTATPLVDAVTTVEATALPRSSGLPVTKICT TAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPAVPQPPVTTQKSADTHPKPTGLSLTS NMTLNLVTSADYKLPSPTSPLSPHSNKSSPRYSKSLMETYVVITLPSEPGTPTDSSASQA ITSWPLGSPPKDLISIEPVFSVVPPLTTAGMPSTSEQSLYLSGTLETFSALPVTALSSFQ AAPTSGTQFFTTEVSKAEVSAARSAVPSVGLSSVTISVPPEPLALDNLHLEKRQHKENGK VQLVGDAIDLRTVPKVEVKATEKCMDLSASTMDMKRQITASDIYGRQMSAVQPSIINLSA TPSVVRPMAVVTETVTVATCAASSSYTTGAESLMGTAHATTAPLQLTTSKHAEPPYRIPS GQVFPAVREDAPINLSLGTSAHPVTSAITKPVTVPPVGVTNGWTDGITSQGVTDGEVVDL STTKSHRTVVTMDESTSGAVTKIIEDDEKPVDLTAGRRAVCCDMVYKLPFGRSCTAQQPP TTLPEDRFGYRDDHYQYDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYKSKNAFDYSGGT DAAVDLTSGRITTGEVMDYSSKTTGPYPETRQVISEVGISTPQYSIARMTPPPGSQYGVG SVLRSSNGVVYSSVATPIPSTFAITTQPGSIFSTTVRDLSGVHTADTVTPLSALHQSQPM PRSYFLTTGASETDIAATGIDINASLQTLTMETLAAETIDAVPTLTTASEVFSEVVGDEN AILIVPEEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEE LQSMKQHLLYQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYN YDPSGTASPQTTTEQAVLEGQYAAPEGSPFWATEDATTTASAVVAIEIPQSQGWYTVQSD GVTQYIAPPGILSTVSEIPLTDVVVKDEKPPKKRSSAAKVRGQYDEIGDSDDPRCFKKIV DSGVQTDDEDAADRSYVSRRRRTKKSVDTSVQTDDEDQDEWDVPTRARRKARAGKYGDST AEADKTKPLVSKVSSIAVQTVAEISVQTEPVGTIRTPSIRARVDAKVEIIKHISAPEKTY KGGSLGCQTEAESDTQSPPYLSATSPPKDKKRPTPLEIGYSSHLRADSTLQLAPSPPKSP KVLYSPISPLSPGKALESAFVPYEKPLPDDISSQKVLHPDMAKVPPASPKTAKMMQRSMS DPKPLSPTADESSRAPFQYTEGYTTKGSQTMTPSGTQKKVKRTLPNPPPEETSTGTQSTY STMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRY LEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAP QTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTPYTQQSHFQQQTLYHQQVS PYQTQPTFQAVATMSFTPQAQPTPAPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEV IRNQPLMIAPVSTDNTYAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDH HTPRNYVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRSTETRRSQEVTDFLAPLQT SSRLHSYVKAEEDPMEDPYELKLLKHQIKQEFRRGAESLDHLAGLSHYYHADTGYRHFPK SEKYSISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYM TSSTSSIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTLRSALQDEAD KPYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFGHASPSGRTKPT SLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPE VQQHMREESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLENGHGLD RKLPERLVHSRPVSQHQEQIMQMNGKTVHYIFPHARIKITRDSKDHTVSGNGLGIRIVGG KEIPGHNGEIGAYIAKILPGGSAEQTGKLIEGMQVLEWNGIPLTSKTYEEVQSIISQQSG EAEICVRLDLNMLSDSENPQHLELHEPPKAVDKAKSPGVDPKQLAAELQKVSLQQSPLVL SSVVEKGSHVHSGPTSAGSSSVPSPGQPGSPSVSKKKHSSSKPTDATKVVSHPITGEIQL QINYDLGNLIIHILQARNLVPRDNNGYSDPFVKVYLLPGRGQVMVVQNASAEYKRRTKYV QKSLNPEWNQTVIYKSISMEQLKKKTLEVTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTP RWYSLKEQTESIDHGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPG SSKSSSEGHLRSHGPSRSQSKTSVTQSHLEDAGAAIAAAEAAVQQLRLQPTKPTNHRPAE SSVSTGSSGSSFGSGYSVDSEGSSSTAGETNLFPIPRIGKMGQNGQEPVKQPGVGVGLAD TEVKTQVMGEIKIALKKEMKTDGEQLIVEILQCRNITYKFKSPDHLPDLYVKIYVMNIST QKKVIKKKTRVCRHDREPSFNETFRFSLSPAGHSLQILLFSNGGKFMKKTLIGEACIWLD KVDLRKRIVNWHKLLVSPTQTH NT seq 15549 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaggcgagcttggaaggggaaggtctcccggaagggctggcggcggcagcg gcggcggcagcagccggaggaggggctggcggggcagggagctccttgcacaccgtgatc ccggccggcatggaggcggatctgagccagctgagcgaagaggagaggagacagatcgcc gctgtcatgtcaagggcgcaggggctgcccaagggaagcgttcccccggccgctgcggag ccgccttccatgcacaggaagcaagagttggatagtagtcaccctccaaagcaaccagga aaaccgccggaccctgggcgttcggctcagcctggtctcagtaagagtagaactacagac actctgaggtcagagcaaaagtcgcctggaaggagtccttccactattagcttgaaagaa tcaaagtccagaactgatttgaaggaagagcacaagactagtatgatgcctggcttcctc tcagaggttaaccctttaagtgctgtctcctctgttgtaaataaattgaatccttttgat ttgatatcagactctgatgcatcccaggaagaaactgccaagaaacaaaaagtagctcag aaagaacaaggaaaaccggaaggaatcacaaagcctccatcacaaccgtcacctaagcca ggtccaaagcagcaaggacctgtgagggtcccaccacagcaggatggctctcccaaatca gtatcttctcagcaaccagaaaaaatgaagtcacaacctccagggacaggcaagccaatt cagggacttacccagtcacctcagacagaccaggcacagtggccacttcaaagagatgca gccaggcctcagactaaacagtctgatgctgtaaggggagaatctgttaaacctgcactg caaagcccatccaaacaacctattcagcaagcaagccctggaaaacctgcagcccagcaa cctggacctgaaaaagttgccacgccacaccctgggcctgcaaagccctcagctcaacaa ccagggacagcaaagcctgctgttcagcagcctgggccaaagtcttcagctcagcctctt gggcctgtgaagactcaagtacaacaggctgggggagagaaacttccatctcagcagcca gggccagcaaagcccccagcccagcagccagggacaccaaagtccccagctcagctgcct gggcctgcaaaaactccttctcagccggttgggccaacaaagtctctggctcagcagcct agcctggccaagccccctcctcagcagcctagcccggccaagccaccacctcagcagcct ggcccggccaagcccccgcctcagcagcctggaccggccaagccccctcctcagcagcct ggcctggccaagccccctcctcagcagcctggcccggccaagccccctcctcagcagcct ggcccggccaagccccctcctcagcagcctggcccggccaagccccctcctcagcagcct ggcctggccaagccctctcctcagcagcctggcccggccaagccccctcctcagcagcct ggcccggccaagccccctcctcagcagcctggcccggccaagccccctcctcagcagcct ggcctggccaagccccctcctcagcagcctggcccggccaagcccccacctcagcagcct ggtccagcaaagccccctcctcaacagcctggccctgcaaagccttcacttcagcagcct ggtccagtaaaacctccccaacagcctggcccagcaaaggcttcagctcagcagtcttca aaaccagtaagccaaacaggagctgggaaacctctgcagccaccagcttctccatctgcg gcacagactccagtacaaggcctctctaaaaccatctgtcctctttgcaataccactgaa cttctgttgcatgttccagaaaaggccaattttaacacatgcactgagtgtcaaaccact gtatgtagcctctgtggctttaatcccaatcctcatttaaccgagataaaagagtggctc tgtttaaactgtcagatgaaaagagctctaggaggtgatctggctccagttccactatcc cctcagcctaaaccgaagactgcccccgtgactcctccatccgcagtgagcaaaccgtcc ccacagccacagcagacttctccaaagaaggatactgtacccaaacaggatctctcaaag gcccctgaggctaaaaagcccccaccactagtgaaacaaccaaccattcacggatccccc ccagttgcagccaagcagcctcctgtggctgagtcttcatccaagccaacccctcccaag gagccttcggtcccatctgagcaggcaaaggtccccatggctgaggataaaccaaagcag cccaagacagtgaaaccagccacagacgtgtcttcagcaccaacagcagcaaaacctgat actccaagctctaaagtacagttggaggatcaacagataacagcccctcctccgaaaaca gatgctgccaaaccctcacagagttttccaccaacgggagaaaaagtcacccccatcgat tctaaagtcataccccgacctgcatcagattcaaaaattctttcacaccctgggcctagt tcagagactaaaggtcaaaagcaagttgattcagttcaaaagagggaagaacccaagaaa gcacaaaccaaaatgagtccgaagccagatgccaagccaatgccaaaagggtcgcctcca gccccaggcccacaacctaccactggccaaactgcccccccatctcagcagcccccaaag cctcaggagcagtcaagacgcttcagtctgaatctgggaagtattactgatgcccccagg tcacagcccacgacgcctcaagaaactgtgactggaaaactctttgggtttggagcatcg atcttcagccaggcatcaaatttgatctccaccgcaggccagcctgggtctcagtctcag agcgggcctggggccccgacaaaacaaggccctcctcctccacaaccacctcatcagggg ccaccgaaagccacaggtcaggggtcaccagcacctgcaaaggttatccctgtgaaaaaa gaaacgaaagctccagtggctgaaaaattagagcccaaagctgaacaagttccaaccgta aaaagagcagaaactgaaaagaagcctccacttgttaaggatagcaaaccttcagcagca gagcctcaaacgcctgtcctaacgcccaaggtggagaagactcccaaaccagaatcaacc tgtcctctctgcaaaactgaactcaatgtcggttcaaaggagcctcctaacttcaatact tgcacgggatgcaagaatcaagtgtgtaatctctgtggatttaaccctacaccacacttg acagagattcaagaatggctttgtttaaattgccaaacccagagagcaatatcaggacag ctcggagatatgggcaaaatgccatctacaccttcaggaccaaaagcctctcctacgccc gtccctccagaacaaccatctcagaaaacaacaatgcctccccaagcaaaaatgaaaaag aaggaacaagaagtaaaaacagaagctgagcaaatacttccagaaaaagtaaaagaaata ccatcagttgaaaagattctcccaaaggtgaccacagatcacaaacaagagagtcaacta gagaaagataaaacttcagcccctcaagaagaaaagccaccctctgaggacaaaaagtca ctcccagaagaaaaaaagcctcctcctgaagaaaagaaaccaacctctgaagaaaaaaag ccagcacctgaagacaaaaagttacctccagtaacaaaaccatcagctctagaggaggaa cagaaacaagacttatttaaaactcaagtaccaaccactgaagaaaagccagaaggcata gtgactccacaggtagtacaggagacgccaccacagaccaaaatggaagataaaccctgt ggcccgcctccaagtttgcccaaggaagacgatgaggcaactcaaacaatgaaagaacaa ccacaggcagcaggcacagcaaagcctgatcgggtggaacctgggaaagaaaaaacagaa aaggaagatgacaaatcagacacctcaagttctcagcaaccaaaaagcccacaaggtctg agtgacacaggatattcttctgatgggatatcaagttcacttggtgaaattccaagtctt attccaagtgatgaaaaagatttgctcaagggactcaaaaaggactctttttcacaagaa agcagcccttccagcccctcagatttggctaagttagaaagtacggtcctatccattttg gaagctcaggcaagtacacttgttgaagaaaaaacagaaaagaaaacccaacctcctgag gttacttgtgagccgcccaaggaccaaccaaaaactcagagtttatctgaaaccctagaa accacagttgcagaagaggagctcacaaagagtcaagaagaaaaagacatgttaaaaaaa gatagccaacaagatggtccttccagaaaggaccgtgaagagaagtccgagtttgttgat gacacagctactagaagacagtcttatgattcagttgaagacagtagcgaaagtgagaac tcacctcttccacaaagaaaacggagaactagtgttggttcatcgagcagtgatgagtat aaacaggaagatagccaaggatctggtgaagaggaggactttattcgaaagcagatcata gaaatgagtgccgatgaagatgcttcaggttctgaagatgatgagttcattaggagccaa ctcaaagagataagtagcagccttgagagccagaagaaggaagaaacaaaagggaaaggg aaggcgacaccagggaaacataggcgactaactcggaaaagcagtacaagctttgatgat gatgcagggagacgccattcatggcatgatgaagatgatgagactttcgatgaaagtcct gagcttaagtacagagagactaaaagtcaggagagtgaagagcttgtaattgctggagga ggagggctacgtcgattcaaaacaattgaacttaacagcacaatagcagataaatactct gcagagtcctcacagaaaaaaacaactttgtattttgatgaggagccagaattagaaatg gaaagcctgacagactctccagaagataggtcaaggggggaaggatcttctagtcttcat gcttccagcttcacccctggcacatcccctacatcagtgtcgtcactggatgaggacagt gacagtagcccaagtcacaaaaagggagagagcaaacaacaacgtaaagctcggcacagg tcacacggtcctcttttacctactattgaagattcttcagaggaagaagaattgagagag gaagaagaattattaaaggagcaagaaaagcagcgggaattggagcagcaacaaagaaag acttctagtaagaaatcaaagaaagataaagatgaacttcgagcacagagaaggagggaa agaccaaagacaccacccagtaatctctctcccattgaagatgcatctccaacggaggag ttacgtcaggctgcagaaatggaggaactccatcgatcttcttgttctgaatactcacct agcatagagtcagacccggaaggttttgaaataagcccagaaaaaataatagaagtgcaa aaagtttataaattgcccacagctgtgtctttgttctctccaacagatgagcaatctatt atgcagaaagaaggtggccaaaaggcattaaaaagtgccgaggaaatgtatgaagaaatg atgcataaaacccacaaatataaagcttttccaggtgcaactgaacgagatgaaatattt gaaaaagagcctttgtatggcgggatgttaatagaggattatatttatgaatctctagta gaggacacatacaatggttcagtagatggcagtctgctaacaaggcaagaagatgaaaat ggatttatgcagcagagagggaaagatcaaaaaacaagaattccagaacagatttatgaa gatcctatgcaaaaaataacagacctccagaaagagttttatcagttagaaagcttacat tctgttgtgcctcaagaagacatcgtttcaagctcttttatcatcccggaaagccatgag atagtggatctgggtagtatggtaacttctaccagtgaagaaaaaaaattattagatgct gatgctgcctatgaagaactcatgaagaggcaacagatgcagttaacacctggatccagt ccaacccagccccccatcacggacgatatgaccgagtctaccatggactttgacagggta cccgatgcatctttgacatcaagtgttctctcgggggcatctcttacagattccaccagc agtgcaacgctttctatcccagatgtcaaaataacccaacatttctcaacagaagaaatt gaggatgaatatgtaactgattatacaagggaaattcaagagataattgcccacgaatca ctgattttgacctactctgagccttcagaaagtgctacatctgtcccaccctctgacaca ccctctctcacgtcatctgtttcttcagtttgtaccacagatagctcctcacccattact acactggatagcataaccacagtttatacagagcccgtggacatagtaactaaactggaa gattctgagatttcttcatcaacgtattttccaggcagcatcatagactatccagaagaa ataagtgtatctttagatcggactgccgtaccagatggaagaactagtgcggatcatgtt gtgatttccttatctgatatggaacctcctatcatagaatctgtaggaactgtacctgag gggctcattgctgacactgtttccactgactcatctacatctgaaaaagacccagggaag aaagacaagagggacactgggaatggaattattcttgaggttttagaagcttacagagat aaaagggaaaagtctgaggttgaactaacaaaaatgggcttatctgaaactgtgtttgat caccctccttcttctgctggtgccgtggaggagcaagttctagcaacatgctttctgtct ggacaggtctttgatcaagcaaaacctgcatctccattaccatctggcagtccttctgtt acgtctcttccaaagaaaactcatccattctttagaagttcttctttggatgcatcagcc caacctcctcccccacctccccctccccctccgccaccacctcctcctcctccccctcct cctccacctcttcctccaccaacctcacctaaaccacctgttcatcctaaaaaaaagcta acagttacagctccagtgactctaactcctacggctacacctctagttgatgctgttact acagtagaggccacagctcttccaagaagtagtggcttacctgtaacaaaaatatgtacc actgcgcctcctcctgttcctcctaaaccatcttccatcccatctggacttgtatttaca cacagacctgagccaagtaaacctccaattgccccgaaaccagcagttcctcagcctcca gtaactacgcaaaaatcagcagatacacaccccaaaccaacaggtctatctttaacctca aatatgacactaaatttggtgacttcagcagattataaattaccttcccctacttcccca ctttctcctcactctaacaagtcctccccaagatattccaaatccctcatggaaacctac gtggttatcacattgccatctgaacctgggactccaacagattcttcagctagtcaagcg attaccagttggcccctgggatcaccccccaaagacctgatttccatcgaaccagtgttt tctgtagttcctcctttaacaactgcaggaatgccaagtacttcagaacagagcttatac ctctctggaactctggagacattttctgccctccctgtcacagcgctctcttcatttcaa gcagccccaacttcaggaacacagtttttcacaactgaagtttctaaggctgaggtttca gcagccagaagtgcagtccctagtgttggtctcagcagtgtcactatctccgttcctcca gagcctcttgctctagataacctacatttagagaagcgtcagcataaggaaaatggaaag gtgcagcttgttggggatgccattgatttgcgtacggtaccaaaagtggaagtgaaagcg actgaaaagtgtatggatctttctgcttccactatggatatgaaaaggcagatcactgcc agtgacatttatggcagacagatgagtgctgtccaaccctctattataaatctcagcgct actccatcggtagtaaggccgatggccgtggtcactgagacagtgactgttgccacatgc gctgctagttcaagttacaccactggcgcagaaagcctaatgggcacagcacatgcaaca acagcaccactccagcttactacatcaaagcacgctgagcctccctacaggataccaagt ggccaggttttccctgcagttagggaggacgcacccataaacttatccttgggtacctca gcacacccggtgacatcagctattacaaaacctgtgactgtgcctcctgttggtgtcaca aatggatggactgatggcatcacatcccagggggtcactgacggggaagtagtagacctc agtacaacaaagtctcacagaactgttgtaacaatggatgaatccacctccggtgcagtg accaaaataatagaagatgacgaaaagcctgttgacctgactgcagggagaagagccgta tgctgcgacatggtttataagttaccctttggaaggagctgcacagcgcagcagcctcca actactcttcctgaggatcgttttggttatagggatgaccactatcaatatgatcgatca gggccatatggatatagggggattgggggaatgaaaccttccatgtctgacacgaattta gcagaagccggacattttttctataaaagtaaaaatgcttttgattattctggaggaact gatgcagcagtagatctaacttcagggagaattactacaggtgaggtaatggattactca agcaagaccacaggtccatatcccgaaacacggcaagtcatttcagaagttgggattagt accccacagtattccatagccagaatgactccacctccaggatcccagtatggtgtgggg agcgttttgaggtcatctaatggtgttgtctattcttcagtagccactccaattccctcc acatttgctatcaccacacaacctggctccattttcagcaccacggtgagggatttgtct ggtgtgcacacagctgacacagtgacgccattatccgccctgcaccagagccagccaatg cctagatcatatttcctaacaacaggtgcatctgaaacagacattgcggcaaccggtatt gatatcaatgccagtttgcaaactcttacaatggaaacgcttgctgctgagacaatagat gcagtgcccactttaaccacagcctcggaagtgttttctgaagtggtgggagatgaaaac gctattttaatcgtccctgaagaagataaacaacagcagcagctcgacttggagcgtgag ctcttggaactggagaaaattaagcagcagcgttttgctgaggaactggagtgggaacgt caggaaattcagaggttccgggaacaagaaaagatcatggttcaaaaaaagctggaggag ctgcagtctatgaagcagcaccttctctaccagcaggaagaagagcggcaagcccagttc atgatgaggcaggagacgctagctcagcagcagttgcagctggagcagatccagcagctg cagcaacagcttcaccagcagctggaagagcagaagattcgccagatctaccagtataac tacgacccttctggaactgcttctccacagaccacgacggagcaggcagttttggaaggt cagtatgccgccccagaaggcagtccattttgggccactgaggatgcaaccaccaccgcg tccgccgttgtggccattgaaatcccgcagagccaagggtggtacacagttcagtctgac ggtgttactcagtacattgccccacctggcatcctgagtactgtttcagagatccctctg acggacgtggtggtaaaagatgagaaaccgcccaaaaagagaagctctgcagccaaagtc cgtggccagtatgacgaaataggggactctgatgatccccgctgctttaaaaagatcgtg gacagcggcgtgcagaccgacgacgaggacgccgcggatcggagttatgtgagtaggagg aggagaaccaagaagagtgtggatacaagcgtccagaccgacgatgaagatcaggacgag tgggatgtgcctaccagagcaaggaggaaagctcgcgccggcaagtacggtgacagcacc gcggaggccgacaagaccaaacccctggtctccaaagtctccagtatagcagtccaaaca gtagcagagatatctgtgcagactgaacccgttggaaccataagaacaccgtccatacgg gcgcgcgtggatgccaaggtagaaataattaaacacatttcagcacctgaaaagacttac aaagggggcagtttaggatgtcaaacagaagcagaatcagacacacagagtcctccatat ctgagtgccacatctccacccaaagacaagaaacgcccaacacctttagagattggttac tcatctcaccttcgggcagattccacattacagctggctccttccccacccaaatctcca aaagtcctttattcacccatctcaccactttcaccaggcaaagccttagaatcagccttt gtaccttatgaaaaacccctccctgatgatataagttcacagaaagtactgcatccagat atggctaaagtgccccccgcaagtcctaagacagccaagatgatgcagcggtccatgtct gaccccaagcctctgagtccaacagcagatgaaagttccagggctccttttcagtatacc gagggctacacgacaaaaggttctcaaaccatgacaccctctggcacccagaaaaaagtt aaaagaactctgccaaacccaccccccgaggagacctccacaggcactcagtccacatac agcacaatgggcacagtttccaggaggaggatctgcagaaccaacacaatggcacgagcc aagattctccaggatatagacagagagcttgatcttgtagaaagggaatctgcaaagctg agaaagaaacaagcagaacttgatgaggaagaaaaggagattgatgccaagttacggtac ctggaaatgggaattaacaggaggaaggaggcattattaaaggagagagaaaagagagag cgagcctacctccagggagtagctgaggatagggattacatgtctgacagtgaggtgagc agcacccgaccaacccgaatagaaagtcagcatggcatagaacgaccaagaactgctccc caaactgaattcagccagtttataccaccacaaacccaaacagaatctcaactagttcct cctacaagtccttatacacaatatcaatattcatcccctgctcttcctacccaagcacct accccatacacccaacagtcccattttcagcaacagactttgtaccatcagcaggtttca ccttatcagactcaaccaacatttcaggctgtggcaacaatgtccttcacacctcaagct caacctacaccagccccacaaccttcttaccagttaccgtcacagatgatggtgatacaa caaaagccacggcaaactacattgtatttggagcccaagataacttcaaactacgaagtg attcgcaaccaacccctgatgatagcacctgtttctactgataatacttacgctgtttct catcttgggagtaagtataatagcttagacttgagaataggattggaggaaagaagtagc atggcaagcagtccaatatcaagcatatctgcagattctttctatgcagatattgaccat catactccacgaaattatgtcctaattgatgatattggagagattaccaaaggaacagca gcattaagcactgcgtttagccttcatgaaaaggatctgtcaaaaacagatcgtctcctt cgatccactgaaacacgtaggtctcaagaagtgacagatttcctagcacctttacagact tcctcgagattgcatagttatgtgaaagcagaggaagatcccatggaagatccctatgag ttaaagcttctgaaacatcagattaaacaagaattccgtagaggagcagagagcttagat caccttgctggtctttcccattattaccatgctgatacgggttatagacattttcccaaa tctgaaaagtacagcattagcagactcacacttgagaaacaagcagcaaaacaactacca gctgccatactatatcagaaacaatcaaagcataagaaatcactaattgatcctaaaatg tcaaaattttcacccattcaagaaagtagagatcttgagcctgattattcaagctatatg acttctagcacttcatctattggtggcatttcttcccgagcaaggcttcttcaagatgac atcacttttggcctcagaaaaaatattacagaccaacagaaatttatggggtcatctctt ggcacagggctgggcacattaggaaataccctaaggtcggctttgcaggatgaagcggat aagccatacagtagtggcagcagatccagaccttcttccagaccttcttccgtctatggc cttgacttatcaattaaaagagattcttccagctcttccctaagactgaaagctcaagag gctgaagctctagatgtttccttcggtcatgcatcaccttctggcagaactaagccgacc agtttaccaattagccagagcagaggaagaataccaattgtggcccaaaattctgaagaa gaaagtccactcagtcctgttggccagccaatgggaatggccagggctgcagctggaccc cttccaccaatatctgcggataccagggatcagtttggatcaagtcactcattgcctgaa gttcagcaacatatgagagaagaatcacgaactcgaggctatgaccgtgacatagcgttc atcatggatgacttccaacatgccatgtcagacagcgaagcctatcatctgcgtcgtgaa gaaacagattggtttgacaaacccagggagtctcgtttggaaaatggacatggtctggat cgcaaactgccagaaagattggtccactctagaccagttagtcaacatcaagagcaaatt atgcagatgaacgggaagactgtgcactatatctttcctcatgcgaggataaaaataaca agagactcgaaggatcacacagtttcaggtaatggattaggaattagaattgtgggtggt aaagaaatccctggacataatggtgaaattggagcctatattgccaaaattcttcctgga ggaagtgcagaacagacagggaaacttatagaagggatgcaagtattggagtggaatgga attcctttaacttctaaaacgtatgaagaagtgcagagtatcattagtcagcaaagtggg gaagcagaaatatgtgtaagactggacctcaatatgctttcagactctgaaaatccccag cacctggaacttcatgagccaccaaaagctgtagataaagcgaaatccccaggggttgat cctaagcagttggcagcagaactccagaaggtctccctgcaacagtcaccgctggttctg tcatctgtcgtggagaaaggatctcacgttcattcaggccctacatcagcgggatccagt tccgttcccagccccgggcaacctgggtccccctccgtgagcaaaaagaaacacagcagc agcaagcctactgatgcaacgaaggtggtctctcatccgattacaggggaaattcagctt caaatcaactatgatcttggaaatctcataatccatattctccaagcaagaaaccttgtc cctcgagacaacaatggttactcggaccccttcgtgaaagtgtaccttcttcctgggaga ggtcaagtcatggttgtccagaatgcaagtgctgagtacaagaggaggactaaatatgtt caaaaaagtcttaatcctgaatggaatcaaacagtaatttataaaagtatctccatggaa cagctcaagaagaaaaccttggaggtgacagtctgggattatgatagattttcttccaat gactttcttggtgaggtattgattgatttatctagcacatctcatctcgataacactccc agatggtattctctcaaagaacagactgaaagcattgatcatggcaagtctcattccagt cagagcagccagcagtctccaaagccgtctgtcatcaaaagcagaagccatggtatcttc cctgacccatccaaggacatgcaggttcccaccattgagaaatcccacagtagtcccggt agctcgaaatcttcctccgaaggccacctgcgctctcacggaccgtcgcgcagtcagagc aaaaccagcgtcactcagagccacctggaagatgctggggctgccatagccgctgccgaa gccgcggtgcagcagctccgcctgcaaccaacaaagcctaccaatcaccggcctgcagaa agctccgtgtccaccggctcctcgggcagcagctttggcagtgggtatagcgtggacagt gaaggaagcagcagcaccgcaggggagactaatctatttcctattccaaggataggaaag atggggcagaatgggcaagagcctgtaaagcagccaggagtaggagtgggactagcagac acggaggtcaaaactcaggtaatgggagaaatcaagattgcattgaagaaggaaatgaag acggatggtgaacaactaatagttgagattctccagtgcagaaatatcacctataaattt aaatctcccgatcacttaccagatttatatgtaaaaatatatgtgatgaacatctctacc caaaaaaaggtgatcaagaaaaaaacgagagtatgccgacatgatagagagccttcgttc aatgaaacttttagattcagcctcagtcctgctggacattctcttcagattttacttttc tctaatggagggaagtttatgaaaaagaccttgattggcgaagcctgtatctggcttgac aaagtggatctcagaaaaagaatagtcaactggcacaaacttttggtcagtcctactcaa acccattga

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