Mustela nigripes (black-footed ferret): 132019526
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Entry
132019526 CDS
T09425
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp01100
Metabolic pathways
mnp04022
cGMP-PKG signaling pathway
mnp04024
cAMP signaling pathway
mnp04924
Renin secretion
mnp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132019526 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
132019526 (PDE3A)
04022 cGMP-PKG signaling pathway
132019526 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
132019526 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
132019526 (PDE3A)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
132019526 (PDE3A)
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Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
132019526
NCBI-ProteinID:
XP_059258671
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Position
6:62643466..62958014
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AA seq
1137 aa
AA seq
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MAALRDAARVGDQPGHGGEPRVPAVGPDSPAGGTGPARSRDSGRRWGDLVLRPLGCSRKL
SSALCAGSLSFLLALLVRLARGEISPEPARWETAEEAAPGAEGGVVPGLRGGAPGGGAPL
SPWLQPSALLFSLVCAFFWMGLCLLRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLL
SLPAAGVVLSCLAAATWLVLRLRLGVLMIAWTSAVRTVSLISLERFKVAWRPYLAYLAGV
LGLLLARYVEQILPQSAGAAPREHFGSQLIAGTREDTPVFKRRRRSSSVVSAEMSGCSSK
SHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITDLLADPSL
PPNVCTSLRAVSNLLSTQLTFQAIHKPRMNPAVSFSDNYTCSDSEESSEKDKLAIPKRLR
RNLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLQEASPSSAVSPDSWNTPV
MMTLTKSRSFTSTYAVSAANHVNSKKPNRPGALAKISPLSSPCSSPPQGTPASSPVSKIS
AVRFPDSANTTARLGLGSHRALTYTQSAPDLSPQILPPPVICSSCGRPYPQGNPADGPLE
GSSGAIRTPSRTDDTTQVTSDYETNNNSDSSDIVQNEDETDCLREPRRKASACAPYAPEA
MIFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMG
LFEAFKIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGHSTVINDPG
SASDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYDHPGR
TNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIE
AILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQ
WTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMP
GKWVEDSDESGDTDDPEEEEEEEAPNEEETCENNETPRKKTFKRRKIYCQITQHLLQNHK
MWKRVIEEEQRLAGIENPSLDPSAQPPPSEQIQAIREEEEEKGKPRGEEIPAPEQNQ
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atggcagcgctccgcgacgccgcgcgggtcggggaccagcccggccacggtggggaaccc
cgagtccccgcggtgggcccggacagtcccgcaggtggcaccggccccgcacggtcgcgg
gactccggccgccgctggggagacctggtgctgcggccgctcgggtgttcccggaaactt
tcctcggcgctgtgcgcgggctccctgtcttttctgctggccctgctggtgaggctggcg
cgcggagagatcagccccgagccggcgcgctgggagacggcggaggaagcggccccgggc
gcagaagggggcgtcgtcccggggctgcggggaggtgctcctgggggcggcgcgccgctc
agcccctggctgcagccctcggcgctgctcttcagtctcgtgtgtgccttcttctggatg
ggcttgtgcctcctgcgcgccggggtgcgcctgcctctggccgtcgccctgctggccgcc
tgctgcggaggggaagcgctcgtccagattgggctgggcgtcggggaggatcacttactg
tcgctgccggccgcgggggtggtgctcagctgcttggccgccgcgacatggctggtgctg
aggctgaggctgggcgtcctcatgatcgcctggactagcgcggtcaggaccgtgtccctc
atttccttagagaggttcaaggtcgcctggagaccgtacctggcgtacttggccggtgtg
ctggggctgctcctggccaggtacgtggagcaaatcttgccgcagtccgcgggggcggct
ccgagggagcatttcgggtcccagctcattgctgggaccagggaagatacccccgtgttt
aagaggaggaggcggtccagctccgtggtgtccgcggagatgtccggctgcagcagcaag
tcgcatcgtaggacctccctgccctgcataccgagggaacagctcatgggtcattcagaa
tgggatcacaaacgagggccaagaggatcacagtcctcaggaaccagtattactgtggat
attgccgtgatgggggaggctcacggcctcattactgacctcctggcagacccttcactg
ccccccaacgtgtgcacatccttgagggcagtgagcaacctgctcagcacccagctcacc
ttccaggctattcacaagccccgcatgaatcctgctgtttccttcagtgacaattacacc
tgttctgattctgaggaaagctctgaaaaagacaagctggctattcccaagcgcctgagg
aggaatttgcctcctggtttgttgagacgagtttcgtcgacttggacaaccaccacctca
gccacaggcctccccactttggagcctgcgcctgtacggagggaccggagtgctagcatc
aaactgcaggaagcatctccatcaagtgctgttagtcccgattcttggaataccccagtg
atgatgaccctcaccaaaagcagatccttcacttcaacctatgctgtttctgcagctaac
catgtaaactcaaaaaagccaaatcgaccaggtgccctagctaaaatttcacctctttca
tcgccctgttcctcacctccccaagggactcctgccagcagcccagtcagcaaaatttct
gcagtgcggtttccagattctgccaacacaactgccaggctgggcctgggttctcacagg
gcattaacttatactcagagtgcccccgacctgtctcctcagatcctccctccacctgtt
atatgtagcagctgtggcagaccgtatccccaagggaatcctgcagacgggcccctggag
gggagcagtggagccattcggacaccaagcagaacagatgacactactcaagttacctct
gattatgaaaccaacaacaacagtgacagcagtgatattgtacagaatgaagatgagact
gactgcctgagagagcctcggaggaaagcttctgcttgtgctccctatgcgcctgaggcc
atgatattcctggacaagccaattcttgctcctgaacctcttgtcatggataacttggac
tcaattatggagcagctaaatacttggaattttccaattttcgatttggtggaaaaaata
ggaagaaaatgtggccgtattcttagtcaggtatcatacagactttttgaagacatgggc
ctttttgaagctttcaaaattccagttagggaatttatgaattattttcatgctttggag
attggatacagggaaattccttatcataacagaatccatgccactgatgtgttacatgct
gtgtggtaccttactacccagccaattccaggccactccactgtaattaatgatcccggg
tcagcaagtgattcagattctgacagtggatttactcatggacatatgggatatgtcttc
tcaaaaatgtataacgtgcctgatgataaatacggatgtctgtctgggaatatccctgcc
ttagagttaatggcattgtatgtggctgcagccatgcatgattatgatcacccaggaagg
acaaatgctttcctggttgcaactagtgctcctcaggcggtgctctataacgatcgttca
gttttggagaatcatcacgcagctgctgcatggaatcttttcatgtcccggccagagtac
aacttcttagttaatcttgaccatgtggaatttaagcattttcgttttcttgtcattgaa
gcaattctggccactgacctgaagaaacactttgattttgtagccaaatttaatgccaag
gtgaatgatgatgttggaatagattggaccaatgaaaatgatcgcctcctggtttgccaa
atgtgtataaagttggctgatatcaatgggccagctaaatgcaaagagctccatcttcag
tggacagagggtattgtcaatgaattttatgaacagggtgatgaagaggccagccttggg
ttaccaataagccccttcatggaccgttctgctcctcagttggccaatcttcaggaatcc
ttcatctctcacattgtgggtcctctgtgcaactcctatgattcagcaggactaatgcca
gggaaatgggtggaagatagtgatgagtcaggagatactgatgacccagaagaagaagag
gaggaggaagcaccaaacgaagaggaaacctgtgaaaataatgaaactccaagaaagaaa
actttcaaaaggaggaagatctactgccaaataactcagcacctcctgcagaaccacaag
atgtggaagagagtcattgaagaggagcagcggttggcgggcatagagaacccatccctg
gacccgtccgcccagccgcctccctcagaacagatccaggccatcagggaagaagaggaa
gagaaagggaagcccagaggagaggagatcccggctccggagcaaaaccagtga
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