Mustela nigripes (black-footed ferret): 132021907
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Entry
132021907 CDS
T09425
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01521
EGFR tyrosine kinase inhibitor resistance
mnp01522
Endocrine resistance
mnp04012
ErbB signaling pathway
mnp04015
Rap1 signaling pathway
mnp04062
Chemokine signaling pathway
mnp04137
Mitophagy - animal
mnp04144
Endocytosis
mnp04360
Axon guidance
mnp04370
VEGF signaling pathway
mnp04510
Focal adhesion
mnp04520
Adherens junction
mnp04530
Tight junction
mnp04540
Gap junction
mnp04611
Platelet activation
mnp04613
Neutrophil extracellular trap formation
mnp04625
C-type lectin receptor signaling pathway
mnp04727
GABAergic synapse
mnp04750
Inflammatory mediator regulation of TRP channels
mnp04810
Regulation of actin cytoskeleton
mnp04912
GnRH signaling pathway
mnp04915
Estrogen signaling pathway
mnp04917
Prolactin signaling pathway
mnp04919
Thyroid hormone signaling pathway
mnp04921
Oxytocin signaling pathway
mnp04926
Relaxin signaling pathway
mnp05100
Bacterial invasion of epithelial cells
mnp05135
Yersinia infection
mnp05152
Tuberculosis
mnp05161
Hepatitis B
mnp05163
Human cytomegalovirus infection
mnp05167
Kaposi sarcoma-associated herpesvirus infection
mnp05168
Herpes simplex virus 1 infection
mnp05203
Viral carcinogenesis
mnp05205
Proteoglycans in cancer
mnp05207
Chemical carcinogenesis - receptor activation
mnp05208
Chemical carcinogenesis - reactive oxygen species
mnp05219
Bladder cancer
mnp05417
Lipid and atherosclerosis
mnp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
132021907 (SRC)
04015 Rap1 signaling pathway
132021907 (SRC)
04370 VEGF signaling pathway
132021907 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
132021907 (SRC)
04137 Mitophagy - animal
132021907 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
132021907 (SRC)
04520 Adherens junction
132021907 (SRC)
04530 Tight junction
132021907 (SRC)
04540 Gap junction
132021907 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132021907 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
132021907 (SRC)
04613 Neutrophil extracellular trap formation
132021907 (SRC)
04625 C-type lectin receptor signaling pathway
132021907 (SRC)
04062 Chemokine signaling pathway
132021907 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
132021907 (SRC)
04915 Estrogen signaling pathway
132021907 (SRC)
04917 Prolactin signaling pathway
132021907 (SRC)
04921 Oxytocin signaling pathway
132021907 (SRC)
04926 Relaxin signaling pathway
132021907 (SRC)
04919 Thyroid hormone signaling pathway
132021907 (SRC)
09156 Nervous system
04727 GABAergic synapse
132021907 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
132021907 (SRC)
09158 Development and regeneration
04360 Axon guidance
132021907 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
132021907 (SRC)
05207 Chemical carcinogenesis - receptor activation
132021907 (SRC)
05208 Chemical carcinogenesis - reactive oxygen species
132021907 (SRC)
05203 Viral carcinogenesis
132021907 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
132021907 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
132021907 (SRC)
05168 Herpes simplex virus 1 infection
132021907 (SRC)
05163 Human cytomegalovirus infection
132021907 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
132021907 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
132021907 (SRC)
05152 Tuberculosis
132021907 (SRC)
05100 Bacterial invasion of epithelial cells
132021907 (SRC)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132021907 (SRC)
05418 Fluid shear stress and atherosclerosis
132021907 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132021907 (SRC)
01522 Endocrine resistance
132021907 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132021907 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mnp04131
]
132021907 (SRC)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132021907 (SRC)
Protein kinases [BR:
mnp01001
]
Non-receptor tyrosine kinases
SRC family
132021907 (SRC)
Membrane trafficking [BR:
mnp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
132021907 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
132021907 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
132021907 (SRC)
Macropinocytosis
Kinases
132021907 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
132021907
NCBI-ProteinID:
XP_059262958
LinkDB
All DBs
Position
7:119118527..119169414
Genome browser
AA seq
553 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagcca
gctgagaatacccacggtggcggcgggggcgccttccccacctcacagacacccagcaag
ccagcctccgctgatggacaccgaggccccagtacggccttcccctccgcagctgctgag
cccaagctgtttgggggcttcaactcctcagacacagtcacctccccgcagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
accgacttgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattcagatggctgcaaagagagggagactggtggctg
gcccactcgctcagcacgggacagacgggttacatccccagcaactatgtggcgccctcc
gactctatccaggctgaagagtggtactttggcaagatcaccagacgggagtcagagcgg
ttactgctcaatgcggagaacccaagagggaccttcctggtgcgagaaagtgagaccacg
aaaggagcctactgcctctccgtgtctgatttcgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagtctgcagcagctggtggcctactactccaaacatgctgacggcctgtgccaccgc
ctcaccaccgtgtgccccacgtccaagccccagactcagggcctggccaaggatgcctgg
gagatccctcgggagtccctacggctggaggttaagctgggccagggatgttttggagag
gtgtggatggggacctggaacggaaccaccagagtggccatcaaaaccctgaagccaggc
accatgtctccagaggccttcctgcaggaggcgcaggtcatgaagaaactgaggcacgag
aagctcgtgcagctgtacgctgtggtgtccgaggagcccatctacatcgtcacggagtac
atgagcaaggggagcctgctggactttctcaagggggagacaggcaagtacctgcggctg
ccgcagctggtggacatggctgctcagatcgcctcaggcatggcctatgtggaacggatg
aactatgtccaccgggacctccgtgctgccaacatcttggttggagagaacctcgtgtgc
aaagtggctgacttcgggctggctcggctcattgaagacaacgaatacacagcccgacaa
ggtgccaaattccccatcaagtggacggctccagaagcggccctctacggccggttcacc
atcaagtcagatgtgtggtcctttgggatcctgctgacggaactcacgacaaagggtcgg
gtgccctaccctgggatggtcaaccgagaggtgctggaccaggttgagcggggctaccgg
atgccctgcccacctgagtgtcccgaatccctgcacgacctcatgtgccagtgctggcgg
aaggagccggaggaacggcccaccttcgagtacctgcaggccttcctggaggactacttc
acgtccaccgagccccagtaccagcccggagagaacctatag
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