Mustela nigripes (black-footed ferret): 132022114
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Entry
132022114 CDS
T09425
Symbol
HELZ2
Name
(RefSeq) helicase with zinc finger domain 2
KO
K25165
3'-5' exoribonuclease HELZ2 [EC:
3.1.13.1
5.6.2.6
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mnp03019
]
132022114 (HELZ2)
Enzymes [BR:
mnp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.13 Exoribonucleases producing 5'-phosphomonoesters
3.1.13.1 exoribonuclease II
132022114 (HELZ2)
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.6 RNA 3'-5' helicase
132022114 (HELZ2)
Messenger RNA biogenesis [BR:
mnp03019
]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Other 3'-5' decay factors
132022114 (HELZ2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_12
AAA_11
RNB
AAA_30
AAA_19
ResIII
AAA_22
PhoH
UvrD-helicase
nSTAND3
UvrD_C_2
Viral_helicase1
SLFN-g3_helicase
zf-met
zf-C2H2_jaz
AAA_24
Helicase_RecD
Motif
Other DBs
NCBI-GeneID:
132022114
NCBI-ProteinID:
XP_059263408
LinkDB
All DBs
Position
7:complement(140028480..140043346)
Genome browser
AA seq
2937 aa
AA seq
DB search
MLSPRSGSSPTSPMATKEQSLARLCAQVDLHLGCPHCTQRLNESTYVLRRTEHHCPREIL
LARFRGATKSRVWRKVARRPSFPRPARYDVCWYYSPGLGCRRHGNQCTFARSREEALVWN
FEREHNVGRLWLKTELQGGGAQGEQHSPADAIRAEHGGHFQLLCSHCFRSCPPRLCPMDA
QGHCPQHGACPSLLAHVSAEGRRKQQVVEVRPQPQYGQPLAYCMYVGRGRPCRHGASRCQ
YAHSAVEMAVWEAEQLGGLQRRDLLSPTAPREDECAAPCGQPPSVRLYCRACLVTCPSQE
AFENHCSSLDHAQMVALDPAEIWEHRSPPTGLSAFELCPNPDLCEYGDACTKAHSEPELQ
EWVRRAQGLELREQAAWQEGLVSYQARLLAEYQRSRSEVLVLAETVDGVSVTCNQPLVHQ
APEKKTRHSWVFDIRSEEPLLYVALLKQELGADFSLVAPRLPPGQLYAKGERFRVRAAPA
GFRVEVRVQGASFGCFEQWVVFDFGRRPALLRKLGLLLGQVHCPGPQGRPACGHAEELER
WHTGNRHVVPGVERTAEQVALVAKYKVPALALDFSPGGSVPGPMSCADYRPRVHQFLYEE
EAAQQRLVARLNFRGPVSLRTALETPALGMLFPPSGALYAEVPTPSARMPDTDEGFLLGR
AVSTALVAPVPAPDRTVFEVQLETRASSERAVWLLLPARCCVALGLRPDTSPFLEVQFQI
DPLTFRFWHQAVDALPDVRLVVPDLPTCSLPRSLPAPPAMRGNHKQKLAVALIAGSSPGG
VRPIAPLLIYGPFGTGKTYTLAMASLEVIRQPHTRVLICTHTNSAADIYIEEHFHRYVSS
GHPEATPLRVMFTDRPPSQTDAATLRYCLLTGDRRAFRAPTRAELEQHRIVVATASQARE
LRVPSGFFSHILIDEAAQMLECEALTPLRYAGPGTRLVLAGDHRQVTPRLFSVPSAQAAG
HTLLCRLFWHYQREAHAVARHSRLIFHENYRCTEAILQFVSRHFYLAEGSPIHASGRVPR
HPTHYPLMFCHVAGNPERDLSHASWLNAAEIAQVVEKVQEIYQTWPPCWGSREQRHICAV
SHGAQVVALRQELRKRDLGQVSVGSFEILPGREFRAVVLSTVHSCSSLLSCGAPALGFFT
DARVLNTVMTRAQSQVVAVGNAVALCSFGACSKLWKSFIRECMKHCSVWPESLSLEHIEQ
SAVQSRRQRWALHAERSVAAVAQDAVPQEGTTGALATEHVATDEVAPEAEGKTSPPETLA
AGGEAAQSTEAGDAALASAAGGCRAVRETATVPPEAEDRTSAGNSSVGDVAPGKAVAGLP
ATEDGDPEDLEDSESDFWPSDLELNADDSILQELLDEARNLAVTVREDGLLDAVAQPESP
QQARQYRSLPRAALRKLLSLEPELYRPCAFMQETFERALAIPLDDTDCGPIHIRGRLHCG
MAFSGDEVLVEVLGADRGPSGRLQGRVVGVLKRKRRELVFVCRTDEWDPRIMTPIDGSVT
KIFVAELKDPLQVPVHCVQQGRVRRVGYERLPAEARGSRLFLVRVVLWRPRFYYPLGIIL
EVLPEATTWEQSLRILDLEHGLRAPGPEPASVSKALQKYRAELSRAPDRREDCRGFLTFT
VDPQGACYLDDALSVRDLGSRYEVAVHIADVASAVPRDGPLDLEARRRGVTFYAPDREPQ
PMLPASLCQDALSLLPGQDRLAVSLFLTVEKGSDQLKGLHIAPSVIRSDRQLSYEEAEHI
IRQHPGAGGELPSLLDSVDACVVAACHFSRVLRRVRLETDAHYEQPSEDGVLGFRAAHTM
VKEYMIQFNRLVAELLVSSECTRTVTLLRWQPAPSERQLAALEEKHGELVPLSLHLRHHL
RGCGSPGRQVYLLATLWRHLQRAACAGDHNLLADLITTDDVHPSLAPVGLDLRKALGRSV
FGRSRQGEQQAAGHYALRVDWYTWATSPIRRYLDVVVQRQVLLVLGHGGAPYSARDIDGL
CQEFSHQHARAQAYQRQARSLHLAAQLRVQPRGKLGIVAGVEMGARGFKLLFPTNPETLP
DPCPVQYRALQLAEHPRDLAGRPGLRLEWRRRIYSVQAEGLRSPQPGTLLDPHTRRVDAA
RWEQLLELVQAERWPEAAALVRELGTAEPPPRELGRVRHSRCGHFVEVSRELGSGDVLQV
QLSACPQRGFLVPSLQLCTVAPGLTLCLQHVERPGDCFLDQAPRAAQDRCLDEGEYARVW
GPFCSLESAAGAVSEGDSITLQQVSVSWDTKQVAQGRLCGSFCLEPSFLSEHGIDLGFGH
CYLCIRLEGLPAMPVTGELHPPAGPGRPPLLSIDPDTYTWVAHGLTGHWDPKEGQADRQE
TSRQVYFFVQHMPMEKVPEEVLRSGTRFTIEVLPKQLPDIRKEEAVSRLDRASPLVVSIA
LGRPIPPPFRLAPEQTLHRGTYSRLLEKRMFDLPGGRHTLNSSQNRAVRAALQKPFTVIQ
GPPGTGKTVVGFHIVFWFHKANEEQVMAWGAPREEELLGDPCVLYCGPSNKSVDVLAGLL
LSRRAELKPLRVYSEQAEATEFPGPSVGSSGPPRKTPREGRPNQSLRSITLHHRVRQASN
PYAAVIRGFDARVQKGEVFSKDDLNWYKQVLGKARRFELERHRVILCTCSCAASAGLRRL
AVRQVLVDEAGMATEPETLIPLVAFSGVEKVVLLGDHKQLRPVVRSEQLQNLGLDRSLFE
RYHADAFLLDTQYRMHADICAFPSTEFYKKKLKTWPGLKRPPSVLGHAGKESCSVIFGHV
QGHEQSLLVSTDEGNENSKANPEEVAEVVRIAKQLTLGRTVDPKDVAILTPYNAQAAEIG
KRLGQEGVTGVSVCSITKSQGSEWRYVLVSTVRTCPESDLDQRPTKSWLKRFLGFVVDPN
QVNVAITRAKEGLCFIGDHRLLRCCPLWRRFLDFCEDQQSLVPASQVRVRRRPALSP
NT seq
8814 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccccacggtctggttcgtcacccaccagccccatggccaccaaggagcagtct
ctggccaggctgtgtgcccaggtggacctgcacctgggctgccctcactgtactcagcgc
ctgaatgagagcacgtatgtgctgcgccggacagagcaccactgtccgcgagagatcctg
ctggcccgcttcaggggagccaccaagagcagggtgtggcgcaaggtggcccggcggccc
agcttcccacggcctgcccgctatgacgtctgctggtactacagcccggggctcggctgc
cggcggcacggcaaccagtgcacctttgcccgcagccgggaggaggccctggtctggaac
ttcgagcgggagcacaatgtcgggcgtctgtggctcaagactgagctgcagggtgggggt
gcccagggggagcagcacagccccgcggacgccatccgcgccgagcatggcggtcacttc
cagctgctctgctcccactgcttccggagctgtcctccacggctctgccccatggacgcc
cagggccactgcccccagcacggggcctgcccttcactcctggctcacgtgagcgccgag
ggccgccgcaagcagcaggtagtggaggtgcggccgcagccccagtatggccagccgctg
gcctactgcatgtacgtggggcgcgggcggccgtgccggcacggggcctcccgctgccag
tacgcacacagtgcggtggagatggccgtgtgggaggccgagcagctgggggggctccag
cggcgggacctgctctcgcccactgccccccgagaggacgaatgtgcagctccctgcggc
cagcctcccagcgtccggctgtactgccgtgcctgcctggtcacctgcccctcccaggag
gccttcgagaaccactgctcatccctggaccacgcacagatggtggccttggacccggcc
gagatctgggagcaccgcagcccacccacggggctctccgcgtttgagctctgccccaat
cccgacctctgtgagtacggggatgcctgcaccaaggcgcactccgagccggagctgcag
gagtgggtgcggcgggcgcagggcctggagctgagggagcaggccgcctggcaggagggg
ctggtgtcttaccaggcccggctgctggctgagtaccagcgaagtcgaagtgaggtcctg
gtgctggcggagactgtggacggcgtgtccgtcacctgcaaccagcccttggtgcatcag
gcccccgagaagaagactcggcacagctgggtatttgacatccgctctgaggaacccctg
ctgtacgtggccctgctcaagcaggagctgggagccgacttctcgctggtggccccccgc
ctcccgccgggccagctctatgcgaagggggagcgcttccgagtgcgcgccgccccagcc
gggttccgggtggaggtgcgcgtgcagggcgcctccttcggctgcttcgagcagtgggtg
gttttcgactttggccgccggccggccttgctacgaaagctggggctgctgctgggccag
gtgcactgcccggggccgcagggcaggccggcgtgcggccacgccgaggagctggagcgc
tggcacacgggcaaccgccacgtggtgcccggtgtggagcggacggccgagcaggtggcc
ctggtggccaagtacaaggtgcccgccctggcgctggacttctctcccgggggctccgtc
ccaggccccatgtcctgtgccgactaccgtccgagggtgcaccagtttctctatgaggag
gaggcggctcagcagcggctggtggccaggctgaacttccggggcccggtgtccctgagg
acagccctggagacgccggccctgggtatgctcttcccgccatcaggggccctctatgcc
gaggtccccacaccctccgcgcggatgccggacacggacgagggctttctgctgggccgg
gcggtcagcacagccctggtggcccccgtccccgcacccgaccgcaccgtgtttgaagtg
cagctggagacgcgggcgagctcggagcgggcggtgtggctgctgctgccggcccgctgc
tgcgtggccctggggctgcggcccgacaccagccccttccttgaggtgcagttccagatc
gacccactgaccttccgattctggcaccaggcggtagacgcgctgcctgatgtgcgactg
gtggtgccagacctgccgacatgctccttgccccggtctctgcctgcaccccccgcgatg
cgcggcaaccacaagcagaagctggccgtggcgcttattgcgggtagtagcccggggggc
gtccggcccattgcccccctgctcatctacggcccgtttggcacaggaaagacctacacg
ctggccatggcctccctggaggtcatccggcagccccacaccagggtgctcatctgcacg
cacaccaacagcgcggccgacatctacatcgaggagcacttccaccgctatgtgagcagt
ggccaccctgaggccactccactccgggtgatgttcacggaccgcccgcccagccagacg
gacgcggccacgctgcgctactgcctcctgaccggggaccgccgggccttccgcgccccg
acacgggccgagctggagcagcaccgcattgtggtggccacggcgtcccaggcgcgcgag
ctcagggtgcccagcgggttcttctcgcacatcctcatcgacgaggccgcccagatgctg
gagtgcgaggcgctcaccccgctgcgctacgccgggcccggcacgcgcctggtgctggca
ggggaccaccggcaggtcacgcccaggctcttcagcgtgccgagtgcccaggccgcgggc
cacacgctgctctgccgcctcttctggcactaccagagggaggcccacgccgtggcgcgg
cacagccggctcatcttccacgagaactaccgctgcaccgaggccatccttcagtttgtc
tcgcggcacttctacctggccgagggcagccccatccacgccagcggccgggtcccccgc
caccccacgcactaccctctcatgttctgccacgtggcgggcaaccccgagcgggacctg
tcacacgcatcctggctgaacgcagcggagatcgcgcaggtcgtggagaaggtgcaggag
atctaccagacctggcccccctgctggggcagccgcgagcagaggcacatctgtgccgtg
tcccacggtgcccaggtggtcgcgctgaggcaggagctgaggaagagggacctgggccag
gtgtctgtgggcagctttgagatcctgccagggcgggagttccgggctgtggtgctgagc
accgtgcacagctgcagcagcctgctgagctgcggggcgcccgccctgggcttcttcacc
gacgcccgcgtgctcaacaccgtcatgacgcgcgcccagtcccaggtggtggctgtgggc
aacgccgtggccctctgctccttcggggcctgtagcaagctctggaagagcttcatccgt
gagtgcatgaagcactgcagcgtctggcccgagagcctgtccctggagcacatcgagcag
agtgcggtgcagagcaggaggcagcgctgggccctccacgcagagagatctgtggctgcc
gtggcccaggacgctgtcccgcaggagggcacaacaggggctctagccacagagcacgtg
gccacggacgaggtggcaccagaggctgaagggaagacatcccctcccgagaccttggca
gcgggaggcgaggccgcacagagcacagaggctggggacgcggccctggcgtctgcggcg
gggggctgccgggcggtgagggagaccgccacggtgcccccagaggctgaggacaggacc
tcagctgggaactcgtcggtgggggacgtggccccggggaaggcagtggccgggctgccg
gccacggaagatggggaccccgaggacctcgaggactcggagtcggacttctggccctcc
gacttggagctcaacgcggacgactccatcctgcaggagctcctggatgaagcccgaaac
ttggcagtgaccgtccgggaagacgggctgctggacgccgtcgcccagcccgagtcccca
cagcaggcccggcagtacaggagcctgccgcgggccgcgctgcggaagctgctgagcctg
gagcctgagctgtaccgcccctgcgccttcatgcaggagaccttcgagcgggcgctggcc
atcccactggacgacacggactgcggccccatccacatcaggggccgcctgcactgtggg
atggccttcagcggggacgaggtgctggtggaggtcctgggcgcagacagaggcccctcg
gggaggcttcagggccgcgtggtgggcgtgctgaagaggaagcggcgggagctggtgttc
gtgtgccgcacggacgagtgggaccctcgcatcatgacccccatcgacggctccgtgacc
aagatcttcgtggccgagctgaaggacccgctgcaggttcccgtgcactgcgtccagcag
ggccgtgtgcggcgcgtggggtacgagcggctccccgctgaggcccgcggcagccgactc
ttcttggtgcgtgttgtcctgtggcgaccccgcttctactaccccctgggcatcatcctg
gaggtgctacctgaggctaccacctgggagcagagtctccgcatcctggacctggagcac
ggcctgagggcgccggggccagagccagcctccgtcagcaaggcactgcagaagtaccgg
gcagagctcagtcgggcgcccgaccgccgggaggactgccgtggctttctgaccttcacc
gtggacccccagggtgcctgctacctggacgatgccctcagcgtccgagatctgggctcc
aggtacgaggtggccgtgcacattgccgatgtggccagcgctgtccccagggatgggcct
ctggacctggaggcccgaagacggggcgtgacattctacgcccctgaccgggagccgcag
cccatgctgccggccagcctctgccaggatgcgctcagcctcctgccgggccaggatcgc
ttggccgtctccctcttcctcacggttgaaaagggcagcgaccagctcaaaggcctgcac
atcgcgccctcggtgatccgctctgaccgccagctgtcctacgaggaggccgagcacatc
atcaggcagcacccgggtgccggtggggagctgcccagcctcttggattctgtggacgca
tgtgtcgtggccgcctgccacttctcccgggtgctgcgccgagtccgcttggagaccgac
gcacactacgagcagcccagcgaggacggcgtgctgggcttccgcgcggcccacaccatg
gtcaaggagtacatgatccagttcaacaggctggtggccgagctccttgtgagcagcgag
tgcacgcggacggtcacgctgctgcggtggcagcccgcgcccagtgagcgccagcttgca
gcactggaggagaagcacggggagctggtgcccctttccctgcacctgcgccaccacctg
cggggctgtgggtctcccggccgacaggtctatctcctggccaccctgtggaggcacctg
cagcgcgccgcctgtgctggggaccacaatctgctggcggacctcatcaccacagatgac
gtgcacccctccctggctcccgtgggcctcgacctccgcaaggccctgggccgctctgtg
tttggccgctcccgccagggcgagcagcaggctgcggggcactacgcgctgcgggtggac
tggtacacgtgggccacctcgcccatccgcaggtacctggacgtggtagtgcagcggcag
gtcctgctggtgctgggccatgggggcgccccctactccgccagggacatagacgggctg
tgccaggaattcagccaccagcacgcgcgcgcccaggcctatcagcgccaggcccgaagc
ctgcatctggctgcacagctccgggtccagccccggggcaagctgggcatcgtggcgggc
gtggagatgggcgcccgcggcttcaagctgctctttcccaccaaccccgagaccttgcct
gacccctgccctgtacagtaccgcgccctgcagctggccgagcaccccagggacctggct
gggcggccgggcctgcggctggaatggcggcgccgcatctactcggtgcaggcggaaggg
ctgcgctccccgcagcccggcaccctgttggacccccacacccggcgggtggatgccgcc
cggtgggagcagctgctggagctagtgcaggcggagcggtggcctgaggcggcggccctg
gtgcgggagctgggcacggcagagcccccgccccgggagctgggccgcgtgaggcacagc
cgctgcggccacttcgtggaggtgtcccgggagctgggcagcggggacgtgctgcaggtg
cagctcagcgcctgcccgcagcggggcttcctggtgccaagcctgcagctgtgcaccgtg
gcgccgggcctcaccctctgcctgcagcacgtagagcggcccggcgactgcttcctggac
caggcaccccgggcggcgcaggaccggtgtctcgatgaaggcgagtacgcccgtgtgtgg
gggccattctgctctctggagtcggccgcaggcgccgtctcggagggggactccatcact
ctgcagcaggtcagcgtgtcctgggacacaaagcaggtggcgcaggggcggctgtgcggc
tccttctgcctggagccgtccttcctcagcgagcacggcattgacctcggcttcggccac
tgctacctctgcatccggctcgaggggctgccggccatgcccgttacaggggagctgcac
cccccagctggccccggccggcctcccctcctgagcatcgaccctgacacgtacacttgg
gtggcccatgggctgacaggacactgggacccgaaggagggccaggccgaccggcaggag
acctccaggcaggtgtacttcttcgtccagcacatgcccatggagaaagttccagaagag
gtgctgagatcgggcacccgattcactattgaggtgctgcccaagcagcttcctgacatt
cgcaaggaagaagccgtgagcaggttggaccgtgcgtccccgctggtggtcagcattgcc
ctgggccggcccatccctccgcccttccgccttgctcctgagcagaccctccacagaggg
acgtacagcaggctcctggagaaacgcatgtttgacctccccggaggccgccacaccctg
aactccagccagaaccgggctgtcagggcagccctgcagaagccgttcacagtgatccag
ggcccgccaggcacggggaagaccgtggtgggtttccacatcgtgttctggtttcacaag
gcaaatgaggagcaggtgatggcctggggcgcccccagggaggaggagctgctgggggac
ccgtgcgtcttgtactgcggtccctctaacaagtcagtggacgtcctggcaggactgctg
ctgagcaggagagccgagctgaagccgctgcgggtgtacagtgagcaggctgaggccacc
gaattcccggggcccagtgtgggcagcagcggcccgcccaggaagacccctcgggagggg
aggcccaaccagagcctcaggagcatcaccctgcaccacagggtccggcaggcctccaac
ccttacgcggcggtcatcagggggtttgacgctcgggtgcagaaaggggaggtcttttcc
aaggatgacctcaactggtacaagcaggtgctggggaaggcacggaggttcgagctggag
cggcaccgggtcatcttgtgtacgtgctcgtgtgcggcctcggctggcctcaggaggctg
gctgtgcggcaggtcctcgttgatgaagcgggcatggccacggagcccgagaccctcatc
ccgctggtggccttctcaggggtggagaaggtggttcttctgggggaccacaagcaactg
cggcctgtggtcaggagtgagcagctgcagaatctggggctggaccggtctctcttcgag
aggtatcatgcagatgccttcctgctagacacacagtaccgcatgcacgcggacatctgc
gccttcccctccacggagttctacaagaagaagctgaagacctggccgggcctgaagcgg
ccgcccagcgtcctgggccacgctggcaaggagagctgctctgtcatctttggccatgtg
cagggccatgagcagagcctactggtgtccacagatgaagggaatgaaaactccaaggcc
aacccagaggaggtggccgaggtggtccgcattgctaagcagctgaccctgggtaggacc
gtggaccccaaggacgttgccattctcacgccctacaatgctcaggctgcggagatcggc
aagaggcttgggcaagagggtgtcaccggagtgagcgtgtgctccatcaccaagagccag
ggaagcgagtggcgctacgtgctggtgagcaccgtgcgcacgtgccccgagagtgacctg
gaccagcggccgacgaagagctggctgaagaggttcctgggctttgtggtggaccccaat
caagtgaacgtggccatcacccgggccaaagagggcctctgcttcattggggaccaccgc
ctcctgcgttgttgccctctctggcggagattcctggacttctgtgaggaccagcagagc
ctcgtgcccgccagccaggtgcgcgttcggaggaggcctgccctgtctccctga
DBGET
integrated database retrieval system
