KEGG   Mustela nigripes (black-footed ferret): 132025479
Entry
132025479         CDS       T09425                                 
Symbol
ABL2
Name
(RefSeq) tyrosine-protein kinase ABL2 isoform X1
  KO
K08887  abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
Organism
mnp  Mustela nigripes (black-footed ferret)
Pathway
mnp04012  ErbB signaling pathway
mnp04014  Ras signaling pathway
mnp05208  Chemical carcinogenesis - reactive oxygen species
mnp05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:mnp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    132025479 (ABL2)
   04014 Ras signaling pathway
    132025479 (ABL2)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    132025479 (ABL2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    132025479 (ABL2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mnp01001]
    132025479 (ABL2)
Enzymes [BR:mnp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     132025479 (ABL2)
Protein kinases [BR:mnp01001]
 Non-receptor tyrosine kinases
  ABL family
   132025479 (ABL2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase F_actin_bind SH2 SH3_1 SH3_2 SH3_9 SH3_3 Haspin_kinase SH3_6 ABC1 RGS12_us1 Kinase-like
Other DBs
NCBI-GeneID: 132025479
NCBI-ProteinID: XP_059268794
LinkDB
Position
10:23230470..23347812
AA seq 1188 aa
MGQQVGRVGEAPGLQQPQPRGIRVSSAARPSGRRRDLAGRTTEAGFNIFTQHDHFASCVE
DGFEGDKTGGSSPEALHRPYSCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVA
SGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSR
SAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTTDGKVYVTAESRFST
LAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYG
EVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIV
TEYMPYGNLLDYLRECSREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGEN
HVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIAT
YGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFE
TMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATE
NSASSSAPGFLRGAQAPTGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR
NAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSFTPAQQEANLVPPKCYGG
SFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTLGLRAGKPTAIDDTSKPFPR
SNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEEG
AAPSRERPKAKLLPRGAAALPLRTPSGDPAITEKDSPGAGVAGVAAAPKSKERNGGARLG
MAGVPEDGDQTGWSSPAKAAAALPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKL
LSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSLCSDPTEEPTASTAGQPALETQD
GGKKAAPGAVPGGGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKIS
ADKISKEALLECADLLSSAITEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAV
SKLELSLQELQVSSAAAGVPGANPVLNNLLSCVQEISDVVQRNINLGR
NT seq 3567 nt   +upstreamnt  +downstreamnt
atggggcagcaggtgggccgcgttggggaggctccggggcttcagcagccgcaacctcgc
gggatccgggtcagcagtgcagccaggccctccggccgcaggcgggacctggcggggcgc
accacagaggccggcttcaatatcttcacccagcatgatcactttgccagctgtgtggag
gatggctttgagggagacaagactggaggcagtagtccagaagccttgcaccgcccctat
agttgtgatgttgaaccccaggcactgaatgaagccatccggtggagctccaaggagaac
ttacttggagccactgagagcgaccctaatctctttgttgcactttacgatttcgtagcc
agtggtgataacacactcagcatcactaaaggtgaaaagcttcgagtccttggttataac
cagaatggtgagtggagtgaagttcgctccaagaatggacaaggttgggtgccaagcaac
tacatcaccccagtgaacagcttagagaaacattcctggtaccatggacccgtgtcacgc
agtgcagcagagtatctactcagcagtctaatcaatggcagtttcctggtgcgagaaagt
gagagcagccccgggcagctgtccatctcgctcaggtacgaggggcgtgtatatcactac
aggatcaatacgaccacagatggcaaggtttacgtcactgcggagagccgctttagcacc
ctggcagagcttgtgcaccatcactccacggtggctgatgggctggtgacaacgttacat
tacccagcgcccaagtgtaataagcccacagtctatggtgtgtcccccatccatgacaaa
tgggaaatggaacgaacggatattaccatgaagcacaagcttgggggtggtcagtacgga
gaagtttatgttggcgtctggaagaaatacagccttacggttgctgtgaagacgttgaag
gaagataccatggaggtggaagagttcctgaaagaagctgcagtgatgaaggaaatcaag
catcctaatctggtccaactattaggtgtgtgtactttggagccaccattttacatcgtg
actgagtacatgccgtatggcaacttgctcgattatctccgagaatgcagccgagaagag
gtgactgcggtggtcctgctgtacatggccactcagatctcctctgcaatggagtatcta
gagaagaagaatttcatccatagagatctcgcagcccgtaactgcctcgtaggagaaaac
catgtggtgaaagtggccgactttggcttaagtagattgatgacgggagacacctatact
gcgcatgctggagccaaatttcctattaaatggacagcaccagagagtcttgcctacaat
accttctcaattaaatctgacgtctgggcttttggggtactgttgtgggaaattgctaca
tatggaatgtcaccatatccaggcattgacctgtctcaggtgtatgatctactggagaaa
ggatatcgaatggaacaacctgaaggatgcccccctaaggtttatgaacttatgagagca
tgctggaagtggagccctgctgaccggccgtcttttgctgaaacacatcaggcttttgaa
accatgttccatgactccagcatttctgaagaggtagctgaggagcttgggagagccgcc
tcctcctcatctgttgttccatacctgccccgactgcctatacttccttccaagacccgg
acgctgaagaaacaggtggagaacaaggagaacatcgaaggggcacaggacgccacagaa
aattctgcttctagttcagcaccagggttccttagaggtgcacaggcccccactgggtcc
ccagcactgcctcgaaaacaaagagacaagtcacccagcagcctcttggaagatgccaaa
gagacatgcttcaccagagacagaaagggaggcttcttcagctccttcatgaaaaagaga
aatgctcccacaccccccaaacgcagcagctccttccgagaaatggagaatcaaccccac
aagaaatatgagctcacgggtaacttctcatctgttgcttctctgcagcatgctgatggg
ttctctttcactcctgcccagcaagaggcgaatctggtgccacccaagtgctatgggggg
agctttgcacagaggaacctctgtaatgacgatggcggtgggggcgggggcagtggcacc
gctgggggcgggtggtctggcatcacaggcttctttacaccacgcttaatcaaaaagaca
ctgggcttacgagcggggaaacccacagccattgatgacacttccaagccttttccaagg
tcaaactctacatcttccatgtcctcagggcttccagagcaggataggatggcaatgacc
cttcccaggaactgccagaggtccaaactccagctggaaaggacagtgtccacctcttct
cagccagaagagaatgtggacagggccaatgacatgcttccaaaaaaatcagaggaaggt
gctgctccaagcagggagagaccaaaagccaaacttttgcccagaggagccgcggctctt
cctctcagaaccccctctggggatccagccattacagagaaggactctccaggggcgggg
gtggctggagtggcagctgccccaaagagcaaggagaggaatggtggggcgcgactcggc
atggctggagtcccagaggacggcgatcagacaggctggtcttctccggccaaggctgca
gcagccctcccaaccactcacaaccacaaagtgccagtccttatctcacccactctgaag
cacactcctgctgacgtgcagctcattggcacagactctcagggcaataaattcaaactc
ttatctgagcatcaggtcacatcctctggagacaaggaccgaccccgacgggtaaaacca
aagtgtgccccacccccacccccagtgatgagactactgcagcatccgtccttgtgctca
gaccccacggaagagccgaccgcctctactgcaggacagcccgcactagaaacacaggac
ggagggaaaaaggccgctccgggggcagtacctggcggtgggaaagccgggaggccagtg
atgcctccgcctcaagtgcctctgcccacatcttccatctcgccagccaaaatggctaat
ggcacagcaggtactaaagtggccctgagaaaaaccaaacaggcggctgagaaaatctca
gcagacaaaatcagcaaagaggccctgctggaatgtgctgacctactgtccagtgccatc
acagaacctgtgcccaacagccagctggtggacactggccaccagctccttgactactgc
tcaggctatgtggactgcatccctcagacgcgcaacaaatttgccttccgagaggctgtg
agcaaactggaactcagcctgcaggagctgcaggtgtcttcggccgctgctggggtgccc
ggggccaaccctgtccttaataacttattgtcatgtgtgcaggagatcagcgatgtggtg
cagaggaatattaacttaggaagataa

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