Microtus oregoni (creeping vole): 121462188 Help Entry 121462188         CDS       T08307                                  Symbol Irs2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism morg  Microtus oregoni (creeping vole) Pathway morg04022   cGMP-PKG signaling pathway morg04068   FoxO signaling pathway morg04140   Autophagy - animal morg04152   AMPK signaling pathway morg04211   Longevity regulating pathway morg04213   Longevity regulating pathway - multiple species morg04910   Insulin signaling pathway morg04920   Adipocytokine signaling pathway morg04923   Regulation of lipolysis in adipocytes morg04930   Type II diabetes mellitus morg04931   Insulin resistance morg04932   Non-alcoholic fatty liver disease morg04935   Growth hormone synthesis, secretion and action morg05010   Alzheimer disease morg05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:morg00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     121462188 (Irs2)    04022 cGMP-PKG signaling pathway     121462188 (Irs2)    04152 AMPK signaling pathway     121462188 (Irs2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     121462188 (Irs2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     121462188 (Irs2)    04923 Regulation of lipolysis in adipocytes     121462188 (Irs2)    04920 Adipocytokine signaling pathway     121462188 (Irs2)    04935 Growth hormone synthesis, secretion and action     121462188 (Irs2)   09149 Aging    04211 Longevity regulating pathway     121462188 (Irs2)    04213 Longevity regulating pathway - multiple species     121462188 (Irs2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     121462188 (Irs2)   09164 Neurodegenerative disease    05010 Alzheimer disease     121462188 (Irs2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     121462188 (Irs2)    04932 Non-alcoholic fatty liver disease     121462188 (Irs2)    04931 Insulin resistance     121462188 (Irs2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  121462188 NCBI-ProteinID:  XP_041529533 LinkDB All DBs Position Unknown AA seq 1329 aa AA seqDB search MASAPLPGAPAPAGGEGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDDA AAAGGSPPLPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRSGDGTAATGGSCSASLPGVLGGSAGAAGSDDNY GLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMN IRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRS KSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRVRTA SEGDGGAAAGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSGGCGGRPSKVTLAPAGGA LQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGPHPHLPHPLHHPQGQRPSSG SASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGYMSM DRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATF SGSSGRLCPSFPVSSPKVAYHPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAALRSV GPSSCKSDDYMPMSPTSVSAPKQILQPRSAAAAALPPSGAAVPAPPSGAGRTFPVNGGSY KASSPAESSPEDSGYMRMWCGSKLSMENTDPKLLPNGDYLNMSPSEAGTTGTPPDFFSAA LRGGGEGLKGVPGHCYSSLPRSYKAPYCSGDSDQYVLMSSPVGRILEEERLEPQATSGTS QLAGTFGAAGGGHTQPHHSAVPSSMRPSGGSGRPEGFLGQRCRAVRPTRLSLEGLQTLPS MQEYPLPSEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSLGSGTP GTSSDSRQRSPLSDYMNLDFSSPKSPKPVAHSGDTVGSMDGLLSPEVSSPYPPLPPRPSA SPSSLQQPLPPAPGELYRLPPASVATSQGPTAGSSTSSEPGDNGDYTEMAFGVAATPPQP IAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRR HSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSCILGGSDEPPTSPGQAQ PSPAVPPAPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVRDEQGSLS PSQPQHPQPGDKSSWGRTRSLGGLLSTVGSTGTGGVCGGPGPGALPSASTYASIDFLSHH LKEATVVKE NT seq 3990 nt NT seq  +upstreamnt  +downstreamnt atggctagcgcgcccctacccggggcccccgcgccggcgggcggggagggcccgaacctc aataataacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgttgcgcggccccggcacgggcggcgacgatgca gccgctgctggggggtcgccgccgctgccaccgaggctggagtactatgagagcgagaag aagtggaggagcaaggcgggcgcgccgaagcgagtgatcgcgctcgactgctgcctgaac atcaacaagcgcgcggacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggcggcggagaacgagcaggagcaagagggctggtaccgcgcgctcacc gacttggtcagcgagggtcgctctggcgatgggactgcggccaccggcgggtcctgcagc gcctctctcccgggcgtcctgggcggctcggcgggtgccgctggctccgatgacaactac gggctcgtgacgcccgccacggcagtctaccgtgaggtgtggcaggtgaacctgaagccc aagggcctgggtcagagcaaaaacctgactggtgtataccgtctatgtctgtctgcgcgc accatcggcttcgtgaagctcaattgcgaacagccgtcggtgacgctgcagcttatgaac attcgccgctgcggccactcagacagcttcttcttcatcgaagtgggccgctctgccgtc accggccccggcgagctgtggatgcaagccgacgactcggtggtggcgcagaacatccac gagaccatcctggaggccatgaaggctctcaaggagctctttgagttccggcctcgcagc aagagtcagtcgtccgggtcgtcggccactcaccccatcagtgtgccgggcgcgcgccgc caccaccacctggtcaacctgccccctagccagaccggcctggtgcgccgctcacgcacc gacagcctggcggccaccccgccagcagccaagtgcacctcatgtcgggtccgtacggcc agcgagggcgatggcggcgcggcagccggggcagggacagcgggaggcaggcctatgtcg gtggccgggagccccctgagtcctgggccggtgcgcgcgcccctgagtcgctcgcacacc ctgagtggcggctgcggaggccgcccgagcaaagtgacgctggcgccggcagggggcgcc ctgcaacacagccgttccatgtccatgcccgtggcgcactcaccgcccgctgccaccagc cccggcagcctatcctccagcagtgggcacggctcgggctcctacccgctgcctccaggc ccccacccgcacctgcctcatccgctccaccacccccaaggccagcgtccatccagcggc agtgcctctgcctccggctcccccagtgaccctggttttatgtcccttgatgagtatggc tccagccctggcgacctgagagccttcagtagccaccggagcaacacgcccgagtcaatc gcagagaccccgccagccagggacggcagtgggggcgaactctatgggtacatgagcatg gatagacccctgagccactgtggccgcccttaccgtagggtctctggggatggggcccag gacctggacagagggctgaggaagaggacttattccttgaccacacctgcccgacagcgg ccagtaccccagccttcctctgcctcccttgatgagtatactctcatgcgggccaccttc tctggcagttcaggtcgcctctgcccatccttccccgtgtcttctcccaaagtggcctat cacccttacccagaggactatggagacattgagattggctcccacaagagttccagcagt aacctgggggcagatgatggttacatgcccatgacccctggggctgccctcaggagtgtt ggccccagtagctgcaagagtgacgactacatgcccatgagccccaccagcgtgtctgcc cccaagcagatcctgcagccgaggtcagcggcggcagcagccttgccaccctcgggagct gcagtgccagcacccccttcaggggcaggcaggaccttccccgtgaacggaggcagctac aaagccagctccccagccgagagctctccggaggatagcgggtacatgcgaatgtggtgt ggctccaagctgtccatggagaacacagacccaaagctgctccccaacggggactacctc aacatgtcccccagcgaggctggcaccacgggcacgccacccgacttcttctcagcagct ttgcgtggagggggagagggcctcaagggtgtcccaggacactgctacagctctctgccc cgctcttacaaggccccctattgtagtggggacagtgaccaatatgtgctcatgagctcc cctgtggggagaatcttggaagaggagaggctggaaccccaggccacctctggaacctcc cagttggctggcacctttggggcagctgggggtggccatacccagcctcaccactcagca gtgccttcctccatgaggcccagtggcggcagtggccgccctgagggcttcctgggccag cgctgtcgggcagtgcgacccacacgcttgtcgctagagggactgcagacccttcccagc atgcaagagtaccctttaccttcagagcccaagagccctggcgagtatatcaacattgac tttggtgaggcgggtacccgtctgtccccgcctgctcccccactgctggcatcagcggct tcatcctcttcgttgctttcagccagtagtcctgcttcatccctgggttcaggtacccca ggcaccagcagtgacagccggcagcgctccccgctctctgactatatgaacttggacttc agttctcccaagtcccctaaacctgtcgcccatagtggagacacagtaggctccatggat ggccttctctccccagaggtctcatctccatacccacctctgcccccacgtccttctgcc tccccctcttccctgcagcagcctctgccacctgccccaggagagctctatcgcctgcct ccagcatcagttgccacttcccagggccccactgctggttcctcaacatcatcagagcct ggggataatggtgactataccgagatggcctttggtgtggctgctaccccgccacaacct atcgcagcacccccaaagcccgaaggtgcccgagtgaccagtcccacatctggcttgaaa cgcctaagtctcatggatcaggtgtctggggtggaggcctttcttcaagtcagccagccc cctgatccccaccggggtgccaaggtcatccgtgcagacccacagggggggcgacgtcgc cacagctcagagaccttctcctccaccaccacagtcaccccagtgtccccctccttcgcc cacaactctaagcgccacaattcggcctctgtggaaaacgtctctctcaggaaaagcagc gaaggtagttgcatcctgggaggaagtgatgagccgcccacatccccaggacaggcacag ccatcgccggctgtgccaccagccccgcaggctaggccatggaacccaggtcaacctggg gctttgattggctgtcctggaggcagcagttctcccatgcgcagagagacctctgtgggt ttccagaacggcctcaactacattgccattgacgtgagggatgagcaggggtccctgtcg ccatctcagccgcagcacccacagcctggagacaagagttcctggggccggacccgtagc cttgggggacttctcagcaccgtgggaagcactggcacaggcggggtgtgtgggggcccg ggccccggagccttgccctctgccagcacctacgcaagcattgacttcttgtcccaccac ttgaaggaagccacagtcgtgaaagagtga

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