Mus pahari (shrew mouse): 110316808 Help Entry 110316808         CDS       T05929                                  Symbol Jak2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism mpah  Mus pahari (shrew mouse) Pathway mpah01521   EGFR tyrosine kinase inhibitor resistance mpah04062   Chemokine signaling pathway mpah04148   Efferocytosis mpah04151   PI3K-Akt signaling pathway mpah04217   Necroptosis mpah04550   Signaling pathways regulating pluripotency of stem cells mpah04630   JAK-STAT signaling pathway mpah04658   Th1 and Th2 cell differentiation mpah04659   Th17 cell differentiation mpah04725   Cholinergic synapse mpah04917   Prolactin signaling pathway mpah04920   Adipocytokine signaling pathway mpah04933   AGE-RAGE signaling pathway in diabetic complications mpah04935   Growth hormone synthesis, secretion and action mpah05140   Leishmaniasis mpah05145   Toxoplasmosis mpah05152   Tuberculosis mpah05161   Hepatitis B mpah05164   Influenza A mpah05167   Kaposi sarcoma-associated herpesvirus infection mpah05168   Herpes simplex virus 1 infection mpah05200   Pathways in cancer mpah05207   Chemical carcinogenesis - receptor activation mpah05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mpah05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mpah00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     110316808 (Jak2)    04151 PI3K-Akt signaling pathway     110316808 (Jak2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     110316808 (Jak2)   09143 Cell growth and death    04217 Necroptosis     110316808 (Jak2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     110316808 (Jak2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     110316808 (Jak2)    04659 Th17 cell differentiation     110316808 (Jak2)    04062 Chemokine signaling pathway     110316808 (Jak2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     110316808 (Jak2)    04917 Prolactin signaling pathway     110316808 (Jak2)    04935 Growth hormone synthesis, secretion and action     110316808 (Jak2)   09156 Nervous system    04725 Cholinergic synapse     110316808 (Jak2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110316808 (Jak2)    05207 Chemical carcinogenesis - receptor activation     110316808 (Jak2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     110316808 (Jak2)   09172 Infectious disease: viral    05161 Hepatitis B     110316808 (Jak2)    05164 Influenza A     110316808 (Jak2)    05168 Herpes simplex virus 1 infection     110316808 (Jak2)    05167 Kaposi sarcoma-associated herpesvirus infection     110316808 (Jak2)   09171 Infectious disease: bacterial    05152 Tuberculosis     110316808 (Jak2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     110316808 (Jak2)    05140 Leishmaniasis     110316808 (Jak2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     110316808 (Jak2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     110316808 (Jak2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110316808 (Jak2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpah01001]     110316808 (Jak2) Enzymes [BR:mpah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      110316808 (Jak2) Protein kinases [BR:mpah01001]  Non-receptor tyrosine kinases   JAK family [OT]    110316808 (Jak2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  110316808 NCBI-ProteinID:  XP_021046875 Ensembl:  MGP_PahariEiJ_G0014347 LinkDB All DBs Position 1:140822483..140888418 Genome browser AA seq 1132 aa AA seqDB search MGMACLTMTEMEATSTSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGQAEGEYLKFPSG EYVAEEICVAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHTILYRIRFYF PHWYCSGSSRTYRYGVSRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG MAVLDMMRIAKEKDQTPLAVYNSVSYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQF SQCKATARNLKLKYLINLETLQSAFYTEQFEVKESARGPSGEEIFATIIITGNGGIQWSR GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQECSNESRIVTVHKQDGKVLEIELSSLK EALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIHSNCHGPISMDFAISKLKKAGNQT GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGDYNLSGTKRNFSNLKDLLNC YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDAQISPTLQRHNNVNQMVFHKI RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLGVAKQLAWA MHFLEEKSLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLGALDSQRKLQFYEDKHQLPAPKWTEL ANLINNCMDYEPDFRPAFRAVIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPVEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPEGCPDEIYVIMTECWNNNVSQRPSFRDLSLRVDQIRDSMAA NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgtcttacaatgacagaaatggaggcaacctccacatctcctgtacat cagaatggtgatattcctggaaatgctaattctgtgaagcagatagatccagtccttcaa gtgtatctgtaccattctcttgggcaagctgaaggagagtatctgaagtttccaagtgga gagtatgttgcagaagaaatttgtgtggctgcttctaaagcttgtggtattacgcctgtg tatcataatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaatcat gtcttccacatagatgagtcaaccaggcatacaatactctacagaataaggttctacttc cctcattggtactgcagtggcagcagcagaacctacagatacggagtatctcgtggggct gaagctcctcttcttgacgactttgtcatgtcttacctttttgctcagtggcggcatgat tttgttcatggatggataaaagtgcccgtgactcatgaaactcaggaagaatgtcttggg atggcagtgttagacatgatgagaatagctaaggagaaggaccagactccactggctgtc tataactctgtcagctacaagacattcttaccaaagtgcattcgagcgaagatccaagac tatcacattttaacccgaaagcgaataaggtacagatttcgcagattcattcagcaattc agtcaatgtaaagccactgccaggaacctaaaacttaagtatcttataaacctggaaacc ctgcagtctgccttctacacagaacagtttgaagtaaaagaatctgcaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggaaacataaggaaagtgagacactgacagaacaggatttacagttatattgtgatttt cctgatattattgatgtcagtattaagcaagcaaaccaggaatgctcaaatgaaagtaga attgtaactgtccataaacaagatggtaaagttttggaaatagaacttagctcattaaaa gaagccctgtcattcgtgtcattaattgatgggtattacagactaactgcggatgcgcac cattacctctgtaaagaggtggctcctccagctgtgctcgagaacatacacagcaactgc catggcccaatatcaatggattttgccattagcaaactaaagaaggcgggtaaccagact ggactgtatgtgcttcgatgtagccctaaggacttcaacaaatactttctgacctttgct gttgagcgagaaaatgtcattgaatataaacactgtttgattacgaagaatgagaatgga gactacaacctcagtgggactaagaggaacttcagtaatcttaaggaccttttgaattgc taccagatggaaactgtgcgctcagacagtatcatcttccagtttaccaaatgctgtccc ccaaagccaaaagataaatcaaatcttctcgtcttcagaacaaatggtatttctgatgct cagatctcaccaacattacagaggcataataatgtgaatcaaatggtgtttcacaaaatc aggaatgaagatttgatatttaatgaaagtcttggccaaggcacttttacaaaaattttt aaaggtgtaagaagagaagttggagattacggtcagctgcacgaaacggaagttctgttg aaagtcctggataaagcacacaggaactactcagagtctttctttgaagcagcaagcatg atgagccagctttctcacaagcacttggttttgaattatggagtatgtgtctgcggagag gagaacattctggttcaagagtttgtaaaatttggatcactggatacatacctgaaaaaa aacaaaaattccataaatatattatggaaacttggagtggctaagcagttggcatgggcc atgcattttctagaagaaaaatcccttattcatgggaatgtgtgtgccaaaaacatcctg cttatcagagaagaagacaggagaacggggaatccacctttcatcaaacttagtgatcct ggcattagcattacagttctaccgaaggacattcttcaggagagaataccatgggtaccg cctgaatgcattgagaatcctaaaaatctaaatctggcaacagacaagtggagcttcggg accactctgtgggagatctgcagtggaggagataagcccctgggtgctctggattctcaa agaaagctgcagttctatgaagataagcaccagcttcctgcacccaagtggacagaatta gcaaaccttataaataattgcatggactatgagccagatttcaggcccgctttcagagct gtcatccgtgatcttaacagcctgtttactccagattatgaactgctaacagaaaacgac atgctacccaacatgagaataggagctctaggattttctggtgcttttgaagacagggac cctacacagtttgaagagaggcacttgaagtttctacagcagcttggcaagggtaacttt gggagtgtggagatgtgccgctatgacccgctgcaggacaacactggagaggtggtggct gtgaagaagctccagcacagcacggaagagcacctccgagactttgaacgggaaatcgaa atcctgaagtccttgcagcatgacaacattgtgaagtacaagggcgtgtgctacagtgcg ggtcggcgcaacctaagattaattatggaatatttgccatatggaagtttacgagactat ctccaaaaacataaagaacggatagatcacaaaaaacttctgcagtatacatctcagata tgcaagggcatggaatatcttggtacaaaaaggtatatccacagggacctggcaacaagg aacatattggtggaaaatgagaacagggttaaaataggagactttggattaaccaaagtc ttgccgcaggacaaagagtactacaaagtaaaggagccaggggaaagccccatattctgg tatgcacctgaatccttgacggagagcaagttttctgtggcctcagatgtgtggagcttt ggagtggttctatatgaacttttcacatacatcgagaagagtaaaagtccacccgtggaa tttatgcgaatgattggcaatgataaacaagggcaaatgattgtgttccatttgatagag ctactgaagaataacgggagattgccaaggccagaaggatgcccagatgagatttatgtg atcatgacagagtgctggaacaacaatgtaagccaacgtccctctttcagggacctttcc cttcgggtggatcaaatccgggacagtatggctgcatga

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