Mus pahari (shrew mouse): 110322912 Help Entry 110322912         CDS       T05929                                  Symbol Jak1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism mpah  Mus pahari (shrew mouse) Pathway mpah01521   EGFR tyrosine kinase inhibitor resistance mpah04151   PI3K-Akt signaling pathway mpah04217   Necroptosis mpah04380   Osteoclast differentiation mpah04550   Signaling pathways regulating pluripotency of stem cells mpah04620   Toll-like receptor signaling pathway mpah04621   NOD-like receptor signaling pathway mpah04630   JAK-STAT signaling pathway mpah04658   Th1 and Th2 cell differentiation mpah04659   Th17 cell differentiation mpah05140   Leishmaniasis mpah05145   Toxoplasmosis mpah05152   Tuberculosis mpah05160   Hepatitis C mpah05161   Hepatitis B mpah05162   Measles mpah05163   Human cytomegalovirus infection mpah05164   Influenza A mpah05165   Human papillomavirus infection mpah05166   Human T-cell leukemia virus 1 infection mpah05167   Kaposi sarcoma-associated herpesvirus infection mpah05168   Herpes simplex virus 1 infection mpah05169   Epstein-Barr virus infection mpah05171   Coronavirus disease - COVID-19 mpah05200   Pathways in cancer mpah05203   Viral carcinogenesis mpah05212   Pancreatic cancer mpah05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mpah00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     110322912 (Jak1)    04151 PI3K-Akt signaling pathway     110322912 (Jak1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     110322912 (Jak1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     110322912 (Jak1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     110322912 (Jak1)    04621 NOD-like receptor signaling pathway     110322912 (Jak1)    04658 Th1 and Th2 cell differentiation     110322912 (Jak1)    04659 Th17 cell differentiation     110322912 (Jak1)   09158 Development and regeneration    04380 Osteoclast differentiation     110322912 (Jak1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     110322912 (Jak1)    05203 Viral carcinogenesis     110322912 (Jak1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     110322912 (Jak1)   09162 Cancer: specific types    05212 Pancreatic cancer     110322912 (Jak1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     110322912 (Jak1)    05161 Hepatitis B     110322912 (Jak1)    05160 Hepatitis C     110322912 (Jak1)    05171 Coronavirus disease - COVID-19     110322912 (Jak1)    05164 Influenza A     110322912 (Jak1)    05162 Measles     110322912 (Jak1)    05168 Herpes simplex virus 1 infection     110322912 (Jak1)    05163 Human cytomegalovirus infection     110322912 (Jak1)    05167 Kaposi sarcoma-associated herpesvirus infection     110322912 (Jak1)    05169 Epstein-Barr virus infection     110322912 (Jak1)    05165 Human papillomavirus infection     110322912 (Jak1)   09171 Infectious disease: bacterial    05152 Tuberculosis     110322912 (Jak1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     110322912 (Jak1)    05140 Leishmaniasis     110322912 (Jak1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     110322912 (Jak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpah01001]     110322912 (Jak1) Enzymes [BR:mpah01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      110322912 (Jak1) Protein kinases [BR:mpah01001]  Non-receptor tyrosine kinases   JAK family [OT]    110322912 (Jak1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 Jak1_Phl FERM_F1 ABC1 RIO1 SH2 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  110322912 NCBI-ProteinID:  XP_021055510 Ensembl:  MGP_PahariEiJ_G0028540 LinkDB All DBs Position 6:complement(52133669..52248038) Genome browser AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSFKKTEVKQVVPEPGVEVTFYLLDREPLRLGSGEYTAEEL CIRAAQECSISPLCHNLFALYDESTKLWYAPNRIITVDDKMSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKRVPEATPLLDASSLEYLFAQGQYDLIKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELS RCHSNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLEYNKHKKDDERNKLR EEWNNFSYFPEITHIVIKESVVSINKQDNKNMELKLSSHEEALSFVSLVDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSMDHFPSLRDLMNHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYSMSQLSFDRILKKDIIQGEHLGRGTRTHIYSGT LLDYKDDEGIAEEKKIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRRSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSDIGPFIKLSDPGIPVSVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICMEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAIQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD FSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggcgttctgtgctaaaatgagg agcttcaagaagactgaggtgaagcaggtggtccctgagccaggagtggaggtgactttc tatctgttggacagggagcccctccgcctgggcagcggagagtatacagccgaggagctg tgcatcagggccgcccaggagtgcagtatctctcctctctgtcacaacctcttcgccctg tacgatgagagcaccaagctctggtatgctccgaaccgaatcatcactgtggatgacaaa atgtctctccggctccactaccgcatgaggttctattttaccaactggcacggaaccaat gacaatgaacagtccgtatggcgacattctccaaagaagcagaaaaacggctatgagaag aaaagggttccagaagcaaccccactcctcgatgccagttcactggagtatctgtttgca cagggacagtatgatttgatcaaatgcctggctcccattcgggaccccaagacagagcaa gacggacatgatattgagaatgagtgcctgggcatggcggtcctggccatctcccactat gccatgatgaagaagatgcagttgccggaacttcccaaagacatcagctacaagcgatat attccagaaacattgaataaatccatcagacagaggaaccttcttaccaggatgcgaata aataatgttttcaaggatttcttgaaggaatttaacaacaagaccatctgtgacagcagt gtgtctacacatgatctgaaggtgaaatacctggctaccttggaaactttgacaaaacat tatggagctgaaatatttgagacttctatgctactgatttcatcagaaaatgaattgagt cggtgccattcgaatgacagtggcaatgttctctatgaagtcatggtgactggaaatctt gggatccagtggcggcagaaaccaaacgttgttcctgttgaaaaggaaaaaaataaactg aagcggaaaaaactggaatataataaacacaagaaggacgatgagagaaacaaactccgg gaagagtggaacaatttttcctatttccctgaaatcacccacattgtaataaaggagtct gtggtcagcattaacaaacaggacaacaaaaacatggaactcaagctctcttctcatgaa gaagccttgtcctttgtgtccctggtggatggctacttccgtctcactgcggatgcccac cattacctctgtactgatgtggctcccccactgattgtccacaatatacagaacggctgt cacggtccaatctgcacagaatatgccatcaataagctgcgtcaagaagggagtgaagag ggaatgtacgtgctgaggtggagctgcactgactttgacaacattcttatgactgtcacc tgctttgaaaagtctgaggtattgggtggccagaagcagttcaagaactttcagattgag gtgcagaagggccgctacagcctgcatggctctatggaccactttcccagcctgcgagac ctcatgaaccacctcaagaagcagatcctgcgcacggacaacataagctttgtgctgaaa cgctgctgtcagcctaagccccgagaaatctccaatctgcttgtagccactaagaaggcc caggagtggcagcctgtctactccatgagccagctgagttttgatcggatccttaagaaa gatattatacaaggtgagcaccttggcagaggcacaagaacacatatctattctgggacc ctgctggactacaaggatgatgaaggaattgctgaagagaagaagataaaagtgatcctc aaagtcctagaccccagccaccgggacatttctctggccttctttgaggcagctagcatg atgagacaggtttcccataaacacattgtgtacctctatggcgtctgtgtccgagatgtg gagaatatcatggtggaagagtttgtggagggggggccgttggatctcttcatgcaccgg agaagtgatgcgcttactaccccctggaagttcaaggttgccaaacagctggccagtgcc ctgagttacttggaagataaagacctggttcatggaaatgtgtgcactaaaaacctcctt ctggcccgtgagggcattgacagtgacattggcccgtttatcaagcttagtgaccctggc atcccagtctctgtgctgaccaggcaagagtgcatagagcgaatcccctggatcgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgacaagtggagctttggaacc acactctgggaaatctgctacaatggagagatccccctcaaagacaagaccctcattgag aaagagaggttttatgaaagccgctgcaggcctgtgactccatcttgcaaggagctagct gacctcatgactcgctgcatgaactatgatcccaaccagagacccttcttccgagccatc atgagggatattaacaagctggaggagcagaatccagacattgtttcagaaaggcagcca acaacagaggtggaccccactcattttgaaaagcgtttcctgaagaggattcgtgacttg ggagagggtcactttgggaaggttgagctctgcagatatgatcccgagggagacaacaca ggggaacaggtagctgtcaagtccctgaagcctgagagtggaggcaaccacatagctgat ctgaagaaggagatagagatcttacggaacctctaccatgagaacattgtgaagtacaaa ggaatctgcatggaagatggagggaatggtatcaagctcatcatggagtttctgccttcg ggaagcctaaaggagtatctgccgaagaataagaacaaaatcaacctcaaacagcagcta aaatacgccattcagatttgtaaggggatggactatttgggttctcggcaatacgttcac cgggacttagcagcaagaaatgtccttgttgagagtgagcatcaagtaaagatcggagac tttggtttaaccaaagcgattgaaaccgataaggagtactacacagtcaaggatgaccgg gacagcccagtgttctggtacgctccggaatgtttgatccagtgtaaattttatatcgcc tctgacgtctggtcttttggagtgacactgcatgagctgctcacttactgtgattcagac tttagtcccatggccttgttcctgaaaatgataggaccaactcatggccagatgacagta actcggcttgtgaatactctgaaagaagggaagcgtctgccatgtccacccaactgtcct gatgaggtttatcagcttatgagaaaatgctgggaattccaaccatctaaccggacaacc tttcagaaccttattgaaggatttgaagcacttttaaaataa

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