Mus pahari (shrew mouse): 110324292
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Entry
110324292 CDS
T05929
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah01521
EGFR tyrosine kinase inhibitor resistance
mpah01522
Endocrine resistance
mpah04010
MAPK signaling pathway
mpah04014
Ras signaling pathway
mpah04015
Rap1 signaling pathway
mpah04066
HIF-1 signaling pathway
mpah04068
FoxO signaling pathway
mpah04114
Oocyte meiosis
mpah04140
Autophagy - animal
mpah04144
Endocytosis
mpah04150
mTOR signaling pathway
mpah04151
PI3K-Akt signaling pathway
mpah04152
AMPK signaling pathway
mpah04211
Longevity regulating pathway
mpah04213
Longevity regulating pathway - multiple species
mpah04510
Focal adhesion
mpah04520
Adherens junction
mpah04550
Signaling pathways regulating pluripotency of stem cells
mpah04730
Long-term depression
mpah04913
Ovarian steroidogenesis
mpah04914
Progesterone-mediated oocyte maturation
mpah05200
Pathways in cancer
mpah05202
Transcriptional misregulation in cancer
mpah05205
Proteoglycans in cancer
mpah05214
Glioma
mpah05215
Prostate cancer
mpah05218
Melanoma
mpah05224
Breast cancer
mpah05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110324292 (Igf1r)
04014 Ras signaling pathway
110324292 (Igf1r)
04015 Rap1 signaling pathway
110324292 (Igf1r)
04066 HIF-1 signaling pathway
110324292 (Igf1r)
04068 FoxO signaling pathway
110324292 (Igf1r)
04151 PI3K-Akt signaling pathway
110324292 (Igf1r)
04152 AMPK signaling pathway
110324292 (Igf1r)
04150 mTOR signaling pathway
110324292 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
110324292 (Igf1r)
04140 Autophagy - animal
110324292 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
110324292 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110324292 (Igf1r)
04520 Adherens junction
110324292 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
110324292 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
110324292 (Igf1r)
04914 Progesterone-mediated oocyte maturation
110324292 (Igf1r)
09156 Nervous system
04730 Long-term depression
110324292 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
110324292 (Igf1r)
04213 Longevity regulating pathway - multiple species
110324292 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110324292 (Igf1r)
05202 Transcriptional misregulation in cancer
110324292 (Igf1r)
05205 Proteoglycans in cancer
110324292 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
110324292 (Igf1r)
05214 Glioma
110324292 (Igf1r)
05218 Melanoma
110324292 (Igf1r)
05215 Prostate cancer
110324292 (Igf1r)
05224 Breast cancer
110324292 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
110324292 (Igf1r)
01522 Endocrine resistance
110324292 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpah01001
]
110324292 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mpah04090
]
110324292 (Igf1r)
Enzymes [BR:
mpah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
110324292 (Igf1r)
Protein kinases [BR:
mpah01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
110324292 (Igf1r)
CD molecules [BR:
mpah04090
]
Proteins
110324292 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Insulin_TMD
B2
DUF4476
Motif
Other DBs
NCBI-GeneID:
110324292
NCBI-ProteinID:
XP_021057394
Ensembl:
MGP_PahariEiJ_G0013077
LinkDB
All DBs
Position
1:39843574..40127787
Genome browser
AA seq
1374 aa
AA seq
DB search
MKSGSGGGSPTSLWGLVFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGFLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTIDWSLILDAVSNNYIVGNKPPKECGD
LCPGTLEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSVCGKRACTENNECCHPECLGSCH
TPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDFCANIPNAESSDSDGFVIHD
DECMQECPSGFIRNSTQSMYCIPCEGPCPKVCGDEEKKTKTIDSVTSAQMLQGCTILKGN
LLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYS
FYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKADKIPIRKYADGTIDVEEVTENPKTEVCGGDKGPCCACPKTEAEKQAEKEEAEY
RKVFENFLHNSIFVPRPERRRRDVMQVANTTMSSRSKNTTVADTYNVTDPEEFETEYPFF
ESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPV
TWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNP
GNYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAILLIVGGLVIMLYVF
HRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVA
KGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVI
MELMTRGDLKSYLRSLRPEVEQNNLVLIPPSLSKMIQMAGEIADGMAYLNANKFVHRDLA
ARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWS
FGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRP
SFLEIIGSIKDEMEPSFQEVSFYYSEENKPPEPEELEMELELEPENMESVPLDPSASSAS
LPLPERHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERALPLPQSSTC
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcgtgtttctctcc
gccgcgctctctctctggccgacgagtggagaaatctgtgggcccggcattgacatccgc
aacgactatcagcagctgaagcgcctggaaaactgcacggtgatcgagggcttcctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcaccgtc
atcactgagtacttgctgctgttccgagtggccggcctcgagagcctgggagacctcttc
ccgaacctcacggtcatccgtggctggaaactcttctacaactacgcactggtcatcttc
gagatgaccaatctcaaggatatcgggctttataatctgaggaacattactcggggggcc
atcaggattgagaagaacgccgacctctgttacctctccaccatagactggtctctcatc
ttggatgcagtgtccaataactacattgtggggaacaagcccccaaaggaatgtggggac
ctgtgtccagggactttggaggagaagcccatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaatcgctgccagaaaatgtgcccaagtgtgtgcggg
aagcgagcctgcaccgagaacaacgagtgctgccacccggagtgcctgggcagctgccac
acaccggacgacaacacaacctgcgtggcctgcagacactactactacaaaggcgtgtgc
gtgcccgcctgcccgcctggcacctacaggtttgagggctggcgctgtgtggaccgcgat
ttctgcgccaacatccccaacgctgaaagcagtgactcggatggcttcgttatccacgac
gacgagtgcatgcaggagtgtccctcaggcttcatccgcaacagcacccagagcatgtac
tgtatcccctgtgaaggcccctgccccaaagtctgcggcgatgaagaaaagaaaacgaaa
accatcgattcggttacctctgctcaaatgctccaaggctgcaccatcttgaagggcaat
ctgcttattaacatccggcgaggcaataacattgcctcggagttggagaacttcatgggg
ctcatcgaggtggtgaccggctacgtgaagatccgccattctcatgccttggtctccttg
tccttcctgaagaacctccgtctcatcttaggagaggagcagctggaagggaactattcc
ttctacgtcctggacaaccagaacttgcagcagctgtgggactggaaccaccggaacctg
accgtcaggtcggggaaaatgtactttgctttcaaccccaagctgtgtgtctctgaaatt
taccgcatggaagaagtgactggaaccaagggacgccagagcaaaggggacataaacacc
aggaacaatggagagcgagcttcctgtgaaagtgatgttctccgtttcacctccaccacg
acctggaagaaccgaatcatcataacgtggcaccggtaccggccaccggactaccgggat
ctcatcagcttcacagtttactacaaggaggcaccctttaaaaacgttacggaatatgac
gggcaggatgcctgtggctccaacagctggaacatggtggatgtggacctgcctccgaac
aaggagggggagcctggcattttactgcatgggctgaagccctggacccagtatgctgtc
tatgtcaaggctgtgaccctcaccatggtggaaaacgaccacatccgtggggccaaaagt
gaaatcttgtacattcgtaccaatgcttcagtcccttccatccccctggatgtcctctcg
gcatcaaactcttcctctcagctgattgtgaagtggaaccccccaactctgcccaatggg
aacctgagttactacattgtgaggtggcagcggcagccccaggatggttacctgtaccgg
cacaactactgctccaaagcagacaaaatacccatcagaaagtatgccgatggtaccatc
gacgtggaggaggtgacagaaaatcccaagacagaagtatgtggtggtgataaagggcca
tgctgcgcttgccctaaaactgaagctgagaagcaggctgagaaggaggaggcagagtac
cgtaaagtctttgagaatttccttcacaattccatctttgtgcccagacccgaaaggagg
cggagagatgtcatgcaagtggccaacaccaccatgtccagccggagcaagaacaccaca
gtagctgacacctacaatgtcacagacccggaggagttcgagacagagtaccctttcttt
gagagcagagtggataacaaggagaggactgtcatctccaacctccggcctttcactcta
taccgcatcgatattcacagctgcaaccacgaggctgagaagctgggctgcagcgcctcc
aacttcgtctttgcgagaaccatgccagcagaaggagcagatgatattcctggtccagtg
acctgggagccaagacccgaaaactccatctttttaaagtggccagaacccgagaacccc
aacggattgatcctaatgtatgaaataaaatacggatcgcaaatcgaggatcagcgggaa
tgtgtgtccagacaggagtacaggaagtacggaggggccaaacttaaccgtctaaaccca
gggaactatacagcccggattcaggctacctccctctctgggaatgggtcatggacagat
cctgtgttcttctatgtcccagccaaaacaacgtatgagaacttcatgcatctgatcatt
gctctgccggttgccatcctgctgatcgttggggggctggttatcatgctgtatgtcttc
catagaaagagaaataacagcaggttgggcaatggagtgctgtatgcttctgtgaaccct
gagtatttcagcgcagctgatgtgtacgtgcctgatgaatgggaggtagctcgagagaag
atcaccatgaaccgagagctcggacaagggtcctttgggatggtctatgaaggagtggcc
aagggcgtggtcaaggatgaacccgaaaccagagtggccatcaagacggtgaacgaggct
gcaagtatgcgtgaaagaatcgagtttctcaacgaggcctcggtgatgaaagagttcaat
tgtcaccatgtggtccggttgctgggtgtggtatcccaaggccagcccaccctggtcatc
atggaactaatgacacgtggcgatctcaaaagttatctccggtctctgaggccagaagtg
gagcagaataatctagtcctcattcctccgagcttaagcaagatgatccagatggctgga
gagattgcagatggcatggcttacctcaatgccaacaagttcgtccacagagaccttgct
gctcggaactgcatggtagccgaagatttcactgtcaaaattggagactttggtatgaca
cgggatatctacgagacagactactaccggaaaggcgggaaggggctgctgcctgtgcgc
tggatgtctcccgagtcgctcaaggatggcgtcttcactactcattctgatgtctggtcc
tttggggtcgtcctctgggagatcgccacgctggctgagcagccgtaccagggcttgtcc
aacgagcaagttcttcgtttcgtcatggagggcggccttctggacaagccggacaactgc
cccgatatgctgtttgaactcatgcgcatgtgctggcagtataaccccaagatgcggccc
tccttcctggagatcatcggcagcatcaaggatgagatggagcctagcttccaggaggtc
tccttctactacagcgaggagaacaagcctcccgagccggaggagctggagatggagctg
gagctggagcccgagaatatggagagcgttccgctggacccttccgcctcctcagcctcc
ctgcctctgcctgaaagacactcaggacacaaggctgagaatggcccgggccctggcgtg
ctggttctccgtgccagttttgatgagagacagccttacgctcacatgaatgggggacgc
gccaacgagagggccttgcctctgccccagtcctcgacctgctga
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integrated database retrieval system
