Mus pahari (shrew mouse): 110325466
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Entry
110325466 CDS
T05929
Symbol
Mapk8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah01522
Endocrine resistance
mpah04010
MAPK signaling pathway
mpah04012
ErbB signaling pathway
mpah04014
Ras signaling pathway
mpah04024
cAMP signaling pathway
mpah04068
FoxO signaling pathway
mpah04071
Sphingolipid signaling pathway
mpah04137
Mitophagy - animal
mpah04140
Autophagy - animal
mpah04141
Protein processing in endoplasmic reticulum
mpah04210
Apoptosis
mpah04215
Apoptosis - multiple species
mpah04217
Necroptosis
mpah04310
Wnt signaling pathway
mpah04380
Osteoclast differentiation
mpah04510
Focal adhesion
mpah04530
Tight junction
mpah04620
Toll-like receptor signaling pathway
mpah04621
NOD-like receptor signaling pathway
mpah04622
RIG-I-like receptor signaling pathway
mpah04625
C-type lectin receptor signaling pathway
mpah04657
IL-17 signaling pathway
mpah04658
Th1 and Th2 cell differentiation
mpah04659
Th17 cell differentiation
mpah04660
T cell receptor signaling pathway
mpah04664
Fc epsilon RI signaling pathway
mpah04668
TNF signaling pathway
mpah04722
Neurotrophin signaling pathway
mpah04723
Retrograde endocannabinoid signaling
mpah04728
Dopaminergic synapse
mpah04750
Inflammatory mediator regulation of TRP channels
mpah04910
Insulin signaling pathway
mpah04912
GnRH signaling pathway
mpah04914
Progesterone-mediated oocyte maturation
mpah04917
Prolactin signaling pathway
mpah04920
Adipocytokine signaling pathway
mpah04926
Relaxin signaling pathway
mpah04930
Type II diabetes mellitus
mpah04931
Insulin resistance
mpah04932
Non-alcoholic fatty liver disease
mpah04933
AGE-RAGE signaling pathway in diabetic complications
mpah04935
Growth hormone synthesis, secretion and action
mpah04936
Alcoholic liver disease
mpah05010
Alzheimer disease
mpah05012
Parkinson disease
mpah05016
Huntington disease
mpah05017
Spinocerebellar ataxia
mpah05020
Prion disease
mpah05022
Pathways of neurodegeneration - multiple diseases
mpah05132
Salmonella infection
mpah05133
Pertussis
mpah05135
Yersinia infection
mpah05142
Chagas disease
mpah05145
Toxoplasmosis
mpah05152
Tuberculosis
mpah05161
Hepatitis B
mpah05162
Measles
mpah05166
Human T-cell leukemia virus 1 infection
mpah05167
Kaposi sarcoma-associated herpesvirus infection
mpah05169
Epstein-Barr virus infection
mpah05170
Human immunodeficiency virus 1 infection
mpah05171
Coronavirus disease - COVID-19
mpah05200
Pathways in cancer
mpah05208
Chemical carcinogenesis - reactive oxygen species
mpah05210
Colorectal cancer
mpah05212
Pancreatic cancer
mpah05231
Choline metabolism in cancer
mpah05415
Diabetic cardiomyopathy
mpah05417
Lipid and atherosclerosis
mpah05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
110325466 (Mapk8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
110325466 (Mapk8)
04012 ErbB signaling pathway
110325466 (Mapk8)
04014 Ras signaling pathway
110325466 (Mapk8)
04310 Wnt signaling pathway
110325466 (Mapk8)
04668 TNF signaling pathway
110325466 (Mapk8)
04068 FoxO signaling pathway
110325466 (Mapk8)
04071 Sphingolipid signaling pathway
110325466 (Mapk8)
04024 cAMP signaling pathway
110325466 (Mapk8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110325466 (Mapk8)
04137 Mitophagy - animal
110325466 (Mapk8)
09143 Cell growth and death
04210 Apoptosis
110325466 (Mapk8)
04215 Apoptosis - multiple species
110325466 (Mapk8)
04217 Necroptosis
110325466 (Mapk8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
110325466 (Mapk8)
04530 Tight junction
110325466 (Mapk8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
110325466 (Mapk8)
04621 NOD-like receptor signaling pathway
110325466 (Mapk8)
04622 RIG-I-like receptor signaling pathway
110325466 (Mapk8)
04625 C-type lectin receptor signaling pathway
110325466 (Mapk8)
04660 T cell receptor signaling pathway
110325466 (Mapk8)
04658 Th1 and Th2 cell differentiation
110325466 (Mapk8)
04659 Th17 cell differentiation
110325466 (Mapk8)
04657 IL-17 signaling pathway
110325466 (Mapk8)
04664 Fc epsilon RI signaling pathway
110325466 (Mapk8)
09152 Endocrine system
04910 Insulin signaling pathway
110325466 (Mapk8)
04920 Adipocytokine signaling pathway
110325466 (Mapk8)
04912 GnRH signaling pathway
110325466 (Mapk8)
04914 Progesterone-mediated oocyte maturation
110325466 (Mapk8)
04917 Prolactin signaling pathway
110325466 (Mapk8)
04926 Relaxin signaling pathway
110325466 (Mapk8)
04935 Growth hormone synthesis, secretion and action
110325466 (Mapk8)
09156 Nervous system
04728 Dopaminergic synapse
110325466 (Mapk8)
04723 Retrograde endocannabinoid signaling
110325466 (Mapk8)
04722 Neurotrophin signaling pathway
110325466 (Mapk8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
110325466 (Mapk8)
09158 Development and regeneration
04380 Osteoclast differentiation
110325466 (Mapk8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
110325466 (Mapk8)
05208 Chemical carcinogenesis - reactive oxygen species
110325466 (Mapk8)
05231 Choline metabolism in cancer
110325466 (Mapk8)
09162 Cancer: specific types
05210 Colorectal cancer
110325466 (Mapk8)
05212 Pancreatic cancer
110325466 (Mapk8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
110325466 (Mapk8)
05170 Human immunodeficiency virus 1 infection
110325466 (Mapk8)
05161 Hepatitis B
110325466 (Mapk8)
05171 Coronavirus disease - COVID-19
110325466 (Mapk8)
05162 Measles
110325466 (Mapk8)
05167 Kaposi sarcoma-associated herpesvirus infection
110325466 (Mapk8)
05169 Epstein-Barr virus infection
110325466 (Mapk8)
09171 Infectious disease: bacterial
05132 Salmonella infection
110325466 (Mapk8)
05135 Yersinia infection
110325466 (Mapk8)
05133 Pertussis
110325466 (Mapk8)
05152 Tuberculosis
110325466 (Mapk8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
110325466 (Mapk8)
05142 Chagas disease
110325466 (Mapk8)
09164 Neurodegenerative disease
05010 Alzheimer disease
110325466 (Mapk8)
05012 Parkinson disease
110325466 (Mapk8)
05016 Huntington disease
110325466 (Mapk8)
05017 Spinocerebellar ataxia
110325466 (Mapk8)
05020 Prion disease
110325466 (Mapk8)
05022 Pathways of neurodegeneration - multiple diseases
110325466 (Mapk8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
110325466 (Mapk8)
05418 Fluid shear stress and atherosclerosis
110325466 (Mapk8)
05415 Diabetic cardiomyopathy
110325466 (Mapk8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110325466 (Mapk8)
04936 Alcoholic liver disease
110325466 (Mapk8)
04932 Non-alcoholic fatty liver disease
110325466 (Mapk8)
04931 Insulin resistance
110325466 (Mapk8)
04933 AGE-RAGE signaling pathway in diabetic complications
110325466 (Mapk8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
110325466 (Mapk8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpah01001
]
110325466 (Mapk8)
Enzymes [BR:
mpah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
110325466 (Mapk8)
Protein kinases [BR:
mpah01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
110325466 (Mapk8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
110325466
NCBI-ProteinID:
XP_021059138
Ensembl:
MGP_PahariEiJ_G0030120
LinkDB
All DBs
Position
8:complement(24662169..24736253)
Genome browser
AA seq
427 aa
AA seq
DB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAMINGSQHPSSSPSVNDMSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaaacgtgacaacaatttttatagtgtagagattggagattctacattc
acagttctaaaacgataccagaatttaaagcctataggctcaggagctcaaggaatagtg
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctcagccggcca
tttcagaatcagacccatgctaagcgcgcctaccgagaactagttcttatgaagtgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaaatccctagaagaa
tttcaagatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggagttagatcatgaaagaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcctagtaatatagtagtcaaa
tcagactgcactttgaagattcttgattttggactggcgaggactgcaggaacgagtttt
atgatgacgccttacgtggtgactcgctactacagagcaccagaggtcattctcggcatg
ggctacaaggagaacgtggatttatggtctgtggggtgcattatgggagaaatggtttgc
cacaaaatcctctttccaggaagggactatattgatcagtggaataaagttattgaacag
ctcggaacaccttgtcctgaattcatgaagaaactacaaccaacagtaaggacttatgtt
gaaaacaggcctaaatatgccggatatagctttgagaaactattccctgatgtgcttttc
ccagctgactcagagcataacaaacttaaagccagtcaggcaagagatttgttatccaaa
atgctagtaatagacgcatccaaaaggatctccgtagatgaagctctccagcacccatac
atcaatgtctggtatgacccttcagaagcagaagccccgccaccaaagatccctgacaag
cagttagatgaaagggagcacacaatcgaggagtggaaagaactgatatacaaggaggta
atggatttggaggaacgaactaagaatggagtcataagagggcagccatctcctttaggt
gcagcaatgatcaatggctctcagcatccatcgtcttcgccgtctgtcaatgacatgtct
tcaatgtccacagatccgactttggcctcggatacagacagcagtctagaagcatcagct
ggacctctgggctgctgtagatga
DBGET
integrated database retrieval system