Mustela putorius furo (domestic ferret): 101683109 Help Entry 101683109         CDS       T07239                                  Symbol JAK1 Name (RefSeq) tyrosine-protein kinase JAK1   KO K11217   Janus kinase 1 [EC:2.7.10.2] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf01521   EGFR tyrosine kinase inhibitor resistance mpuf04151   PI3K-Akt signaling pathway mpuf04217   Necroptosis mpuf04380   Osteoclast differentiation mpuf04550   Signaling pathways regulating pluripotency of stem cells mpuf04620   Toll-like receptor signaling pathway mpuf04621   NOD-like receptor signaling pathway mpuf04630   JAK-STAT signaling pathway mpuf04658   Th1 and Th2 cell differentiation mpuf04659   Th17 cell differentiation mpuf05140   Leishmaniasis mpuf05145   Toxoplasmosis mpuf05152   Tuberculosis mpuf05160   Hepatitis C mpuf05161   Hepatitis B mpuf05162   Measles mpuf05163   Human cytomegalovirus infection mpuf05164   Influenza A mpuf05165   Human papillomavirus infection mpuf05166   Human T-cell leukemia virus 1 infection mpuf05167   Kaposi sarcoma-associated herpesvirus infection mpuf05168   Herpes simplex virus 1 infection mpuf05169   Epstein-Barr virus infection mpuf05171   Coronavirus disease - COVID-19 mpuf05200   Pathways in cancer mpuf05203   Viral carcinogenesis mpuf05212   Pancreatic cancer mpuf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mpuf00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101683109 (JAK1)    04151 PI3K-Akt signaling pathway     101683109 (JAK1)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101683109 (JAK1)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101683109 (JAK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     101683109 (JAK1)    04621 NOD-like receptor signaling pathway     101683109 (JAK1)    04658 Th1 and Th2 cell differentiation     101683109 (JAK1)    04659 Th17 cell differentiation     101683109 (JAK1)   09158 Development and regeneration    04380 Osteoclast differentiation     101683109 (JAK1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101683109 (JAK1)    05203 Viral carcinogenesis     101683109 (JAK1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101683109 (JAK1)   09162 Cancer: specific types    05212 Pancreatic cancer     101683109 (JAK1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101683109 (JAK1)    05161 Hepatitis B     101683109 (JAK1)    05160 Hepatitis C     101683109 (JAK1)    05171 Coronavirus disease - COVID-19     101683109 (JAK1)    05164 Influenza A     101683109 (JAK1)    05162 Measles     101683109 (JAK1)    05168 Herpes simplex virus 1 infection     101683109 (JAK1)    05163 Human cytomegalovirus infection     101683109 (JAK1)    05167 Kaposi sarcoma-associated herpesvirus infection     101683109 (JAK1)    05169 Epstein-Barr virus infection     101683109 (JAK1)    05165 Human papillomavirus infection     101683109 (JAK1)   09171 Infectious disease: bacterial    05152 Tuberculosis     101683109 (JAK1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101683109 (JAK1)    05140 Leishmaniasis     101683109 (JAK1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101683109 (JAK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpuf01001]     101683109 (JAK1) Enzymes [BR:mpuf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101683109 (JAK1) Protein kinases [BR:mpuf01001]  Non-receptor tyrosine kinases   JAK family [OT]    101683109 (JAK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Jak1_Phl FERM_F2 FERM_F1 ABC1 SH2 RIO1 FERM_C_FAK1 Motif Other DBs NCBI-GeneID:  101683109 NCBI-ProteinID:  XP_004762995 Ensembl:  ENSMPUG00000000719 UniProt:  M3XNR7 LinkDB All DBs Position Unknown AA seq 1153 aa AA seqDB search MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEI CIRAAQECCISPLCHNLFALYDENSKLWYAPNRAITVDDKTSLRLHYRMRFYFTNWHGTN DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENELN WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLIDGYFRLTADAH HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPLHCPDEVYQLMRKCWEFQPSNRTT FQNLIEGFEALLK NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg agctctaagaagacagaggtgaatctggaggcccccgagccaggagtggaagtgctcttc tatctttctgatagggagcccctccggctgggcagcggagagtacactgcggaggagatc tgcatcagggctgcgcaggaatgctgtatctctcccctgtgtcacaacctctttgccctg tatgacgagaacagcaagctctggtatgccccgaatcgcgccatcactgttgacgacaag acatccctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa aaaaaagtcccagatgcaacccctcttcttgatgccagttctttggaatatctgtttgct cagggacagtatgatttggtcaaatgtctggctcctattcgagaccccaagaccgagcag gatgggcatgatatcgagaacgagtgtctgggaatggctgtcctggccatctcccactat gccatgatgaagaagatgcagttgccagaactgcccaaggacatcagctacaagcgttat attccagaaacattaaataagtccatcagacagaggaaccttctcaccaggatgcggata aataatgttttcaaggatttcctaaaggaatttaacaacaagactatttgcgacagcagt gtatctactcatgacctaaaggtgaagtacctggccaccttggaaacactgacaaaacat tacggcgcagaaatatttgagacttccatgttactgatttcttcagaaaatgagttgaat tggtttcatccaaacgacagtggaaacgttctctactatgaagtgatggtaactggaaat cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccgg gaagagtggaacaatttttcttatttccctgaaatcactcacattgtaataaaggagtct gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcgtcccatgaa gaggccttgtcctttgtgtccctgatagatggctacttccggctcacagcagatgcccat cattacctctgcaccgatgtggctcccccattgatcgtccacaacatacagaatggttgt cacggtccaatttgcacggaatatgccatcaataagttgcggcaagaaggaagcgaggag gggatgtatgtgctgaggtggagctgtaccgactttgataatatcctcatgacggtcacc tgctttgagaaatctgaggtgctgggtggccagaagcagttcaagaactttcagatcgaa gtgcagaagggccgctatagcctgcacggctcggaccgcagcttccccagcctgggggac ctgatgagccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtgctgaag cgctgctgccagcccaagccccgagagatctccaatctgctggtggctacaaagaaagcc caggagtggcagcctgtctaccccatgagccagctgagttttgaccggatcctcaagaaa gacatcgtgcaaggtgagcatctcgggagaggcacacggacacacatctactccggcacc ctggtggattacaaggatgacgaaggaacttcggaagagaagagaataaaagtgatcctc aaagtcttagaccccagccacagggacatttctctggccttcttcgaagcagccagcatg atgaggcaggtctcccacaaacacatcgtgtacctctatggtgtctgtgttcgagatgta gagaatatcatggtggaggagtttgtggaaggggggcccctggatctcttcatgcaccgg aaaagcgatgtcctcaccacaccatggaagttcaaagttgccaaacagctagccagcgcc ctgagttacttggaggataaagacctggtccatggaaacgtgtgcacgaaaaaccttctc ctggcccgtgagggcattgacagcgagtgtggcccattcatcaagctcagtgaccctggc atccccatcaccgtgctgtccaggcaagagtgcatagaacgaatcccgtggattgctcct gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc acactctgggaaatctgctacaatggcgagatccctctgaaagataagaccctgattgag aaagagagattctacgaaagccggtgccggccagtgacaccatcttgtaaggagctggct gacctcatgacacgctgcatgaactatgaccccaaccagagacccttcttccgagccatt atgagagacatcaacaaactagaagagcagaatccagacattgtttctgaaagaaagccg gcaaccgaagtagatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg ggagagggccactttgggaaggttgagctctgcaggtatgaccctgagggggacaatacc ggggagcaagtggcggtgaagtccctgaagcccgagagtggaggcaaccacatagctgat ctgaagaaggaaattgaaatcctaaggaacctctatcacgagaacattgtgaagtacaaa ggcatctgtacagaagatggaggaaatggtattaaactcatcatggaatttctgccttca ggaagccttaaggaatatcttccaaagaacaagaacaaaattaacctcaaacagcaatta aaatacgctgttcagatttgtaaggggatggactatttgggttctcggcagtatgttcac cgggacttggcagcaagaaacgtccttgttgagagtgagcaccaagtgaaaattggagac tttggtttgaccaaagcaatcgaaactgacaaagagtactacaccgtcaaggatgatcgg gacagccctgtgttttggtatgctcccgaatgtttaattcagtgtaaattttacatcgcc tctgatgtctggtcatttggagtgactctgcatgagttgcttacttactgtgactcagat tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagtc acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacttcactgccca gatgaggtttatcaacttatgagaaaatgctgggagttccaaccatccaatcggacaact tttcagaaccttatcgaaggatttgaagcacttttaaaataa

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