Mycobacterium sp. JS623: Mycsm_02248
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Entry
Mycsm_02248 CDS
T02423
Name
(GenBank) isocitrate/isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00290
Valine, leucine and isoleucine biosynthesis
msa00660
C5-Branched dibasic acid metabolism
msa01100
Metabolic pathways
msa01110
Biosynthesis of secondary metabolites
msa01210
2-Oxocarboxylic acid metabolism
msa01230
Biosynthesis of amino acids
Module
msa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Mycsm_02248
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mycsm_02248
Enzymes [BR:
msa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
Mycsm_02248
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-ProteinID:
AGB22599
UniProt:
L0IUU6
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Position
2212493..2213503
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AA seq
336 aa
AA seq
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MKLAIIAGDGIGPEVVSEALKVLDAVVPGVEKTEYDLGARRYHATGELLTEATIEELRGH
DAILLGAIGDPSVPSGVLERGLLLKLRFALDHHVNLRPGRLYPGVSSPLSGVTGIDFVVV
REGTEGPYTGNGGVLRAGTPQEVATEVSVNTAYGVERVVRDAFTRAQSRRKHLTLVHKTN
VLTFAGGLWSRIFAEVGKDFPDVEVAYQHIDAVTIHMVTDPGRFDVIVTDNLFGDIITDL
AAVVCGGIGLAASGNIDATRTNPSMFEPVHGSAPDIAGQGVADPTAAIMSVALLLSHVGE
HDAAARVDKAVEQHLATRGDAKLTTAQIGERIAASL
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
gtgaaattggcgatcattgccggcgacggcatcggccccgaggtcgtcagcgaggccctc
aaggtgctcgacgcagtcgtccccggcgtcgagaagaccgagtacgacctgggcgcacgg
cgctaccacgccaccggcgaactgctcaccgaagccactatcgaagagttgcgcggtcac
gacgcgatcctgctcggtgccatcggcgacccgtcagtacccagcggggtgctggaacgc
ggcctgctactgaagttgcgcttcgcgctggaccaccacgtcaacctgcggccgggccgg
ctgtatcccggtgtcagcagcccgctttcgggggtgactggcatcgacttcgtcgtcgtc
cgcgagggcaccgagggcccctacaccggcaacggcggcgtgctgcgggccggaactccg
caggaggtggcgaccgaggtcagcgtcaacaccgcctacggcgtcgagcgtgttgtccgt
gacgccttcacccgagcgcaaagccgtcgcaagcatctgaccctggtgcacaagacgaat
gtgctgacgttcgcgggcggtctatggtcgcgcatcttcgccgaagtcggcaaggatttc
ccggacgtggaagtcgcataccaacacatcgacgcggtgaccattcacatggtcaccgat
ccgggccggttcgacgtgatcgtcaccgacaacctgttcggcgacatcatcaccgacctc
gccgcggtggtgtgcggtggcataggactggccgcgagcggcaatatcgacgcgacgcgg
acgaatccgtcgatgttcgaaccggtgcacggcagcgcgccggacatcgcgggtcagggc
gtcgcagatccaaccgcggcgatcatgtcggtggcgctgctgctttcgcacgtcggtgaa
cacgacgccgcggcccgcgtcgacaaggccgtcgagcagcatctcgccacccgcggcgac
gcaaagctgaccacagcgcagatcggcgagcggatcgcggcgagcctttag
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