Mycolicibacterium smegmatis MC2 155: MSMEG_1654
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Entry
MSMEG_1654 CDS
T00434
Name
(GenBank) isocitrate dehydrogenase, NADP-dependent
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
msm
Mycolicibacterium smegmatis MC2 155
Pathway
msm00020
Citrate cycle (TCA cycle)
msm00480
Glutathione metabolism
msm01100
Metabolic pathways
msm01110
Biosynthesis of secondary metabolites
msm01120
Microbial metabolism in diverse environments
msm01200
Carbon metabolism
msm01210
2-Oxocarboxylic acid metabolism
msm01230
Biosynthesis of amino acids
Module
msm_M00009
Citrate cycle (TCA cycle, Krebs cycle)
msm_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
msm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MSMEG_1654
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MSMEG_1654
Enzymes [BR:
msm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
MSMEG_1654
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Paralog
Gene cluster
GFIT
Motif
Pfam:
IDH
Motif
Other DBs
NCBI-ProteinID:
ABK69615
UniProt:
A0QSZ3
Structure
PDB
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All DBs
Position
1748543..1750774
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AA seq
743 aa
AA seq
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MSAQQPTIIYTLTDEAPLLATYAFLPVVRKFAEAAGIDVKTSDISVAARILAEFGDHLTE
EQRVPDNLGELGALTQDPSANIIKLPNISASVPQLLAAIKELQGKGYNVPDYPANPKTDD
EKKIKDRYAKILGSAVNPVLREGNSDRRAPKAVKEYARKHPHSMGEWSQASRTHVATMKT
GDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALIAFYEE
QIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNVNNGLS
DLYDKIEALPASQREEIIEDLHKCHEHRPELAMVDSAKGISNFHSPSDVIVDASMPAMIR
LGGKMYGADGRTKDTKAVNPESTFSRMYQEMINFCKTHGQFDPTTMGTVPNVGLMAQKAE
EYGSHDKTFEIPEDGVADIVDIDTGEVLLTQNVEEGDIWRMPIVKDAPIRDWVKLAVTRA
RLSGMPVVFWLDTERPHEVELRKKVKEYLKDHDTEGLKIQIMPQVWAMRYTLERVVRGKD
TIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEEN
HLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDNR
GSQFYLSLFWAQALAEQTEDAELAERFKPLAKALAEQEEAIVSELNSVQGKTVDIGGYYY
PDPEKTSEVMRPSKTFNTTLESV
NT seq
2232 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcccagcagccgaccatcatctacacgctgaccgacgaggcgccgctgcttgcg
acctatgccttcttgccggtggtacggaaattcgccgaagcggcaggcatcgacgtcaaa
accagcgacatctcggttgcggcccgcatcctggccgagttcggggatcacctgaccgag
gagcagcgggtcccggacaacctgggtgagctgggcgcgctgacgcaggaccccagcgcc
aacatcatcaagctgccgaacatcagcgcttcggtgccgcagctgctcgcggcgatcaag
gagctgcagggcaaggggtacaacgtgccggattacccggccaacccgaagaccgacgac
gagaagaagatcaaggaccgctacgccaagatcctcggcagcgcggtgaaccccgttctg
cgcgaaggcaactcggaccgccgcgcacccaaggcggtcaaggagtacgcgcgcaagcac
ccgcacagcatgggtgagtggagccaggcgtcgcgcacccacgtcgcgaccatgaagacc
ggcgacttctaccacggcgagaagtcgatgacgctggaccgcgaccgccgcgtcaagatg
gtgctcaagaccaagagcggcgaggagatcgtcctcaagcccgaggtcaagctcgacgcg
ggcgacatcatcgactcgatgtacatgagcaagaaggcgctcatcgcgttctacgaggag
cagatcgaggacgcctacaagaccggcgtcatgttcagccttcacgtcaaggcgaccatg
atgaaggtgtcgcaccccatcgtgttcggccacgcggtcaaggtcttctacaaggacgcg
ttcgccaagcacgagaagctgttcgacgagctcggtgtcaacgtcaacaacggtctgtcc
gatctgtacgacaagatcgaggcgctgcccgcgtcgcagcgcgaggagatcatcgaggat
ctgcacaagtgccacgagcaccggccggagctcgcgatggtcgactcggccaagggcatc
tcgaacttccactcgccgtccgacgtcatcgtcgacgcctcgatgcccgcgatgatccgc
ctcggcggcaagatgtacggcgcagacggccgcaccaaggacaccaaggccgtcaacccg
gagtcgaccttctcccgcatgtaccaggagatgatcaacttctgcaagacgcacggccag
ttcgatcccaccaccatgggcacggtgccgaacgtcggactgatggcgcagaaggccgag
gagtacggcagccacgacaagaccttcgagatccccgaggacggcgtcgccgacatcgtc
gacatcgacaccggtgaggtgctgctcacccagaacgtcgaagagggcgatatctggcgc
atgccgatcgtcaaggacgcgccgatccgcgactgggtcaagctggccgtcacgcgcgct
cggctgtccggcatgcccgtggtgttctggctcgacaccgagcgtccgcacgaggtcgag
ctgcgcaagaaggtcaaggagtacctcaaggaccacgacaccgaaggcctgaaaatccag
atcatgccgcaggtgtgggccatgcggtacacgctggagcgggtcgtccgcggcaaggac
accatcgccgcgaccggcaacatcctgcgcgactacctcaccgacctgttcccgatcctg
gagctgggcaccagcgccaagatgctgtcgatcgtgccgctgatggccggcggcggtctg
tacgagaccggggcgggcggctcggcgcccaagcatgtgcaccagctcgtcgaggagaac
cacctgcggtgggattcgctgggtgagttcctcgcactcggcgccagccttgaggacatg
ggcaacaagaccggcaacgagaaggccaaggtgctggccaaggcgctcgacaccgcgacc
ggaaagttgttggaggagaacaagagcccgtcgcgtcgtaccggtgagctggacaaccgc
ggcagccagttctacctgtcgctgttctgggcccaggccctggccgagcagaccgaggac
gccgaactcgccgagcgcttcaagccgctggccaaggcgctcgccgagcaggaggaggcc
atcgtctccgagctgaactcggtgcagggcaagacggtcgacatcggcggttactactac
ccggatccggagaagacctccgaggtgatgcgtccgagcaagacgttcaacaccacgctc
gaatcggtgtaa
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