Mycobacterium tuberculosis KZN 1435: TBMG_00988
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Entry
TBMG_00988 CDS
T00940
Name
(GenBank) D-alanine-D-alanine ligase ddlA
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
mtb
Mycobacterium tuberculosis KZN 1435
Pathway
mtb00470
D-Amino acid metabolism
mtb00550
Peptidoglycan biosynthesis
mtb01100
Metabolic pathways
mtb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mtb00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TBMG_00988
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TBMG_00988
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TBMG_00988
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
mtb01011
]
TBMG_00988
Enzymes [BR:
mtb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TBMG_00988
Peptidoglycan biosynthesis and degradation proteins [BR:
mtb01011
]
Precursor biosynthesis
Amino acid ligase
TBMG_00988
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_3
ATP-grasp_4
CPSase_L_D2
RimK
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
ACT24032
LinkDB
All DBs
Position
1075907..1076983
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AA seq
358 aa
AA seq
DB search
MFGGRSNEHAISCVSAGSILRNLDSRRFDVIAVGITPAGSWVLTDANPDALTITNRELPQ
VKSGSGTELALPADPRRGGQLVSLPPGAGEVLESVDVVFPVLHGPYGEDGTIQGLLELAG
VPYVGAGVLASAVGMDKEFTKKLLAADGLPVGAYAVLRPPRSTLHRQECERLGLPVFVKP
ARGGSSIGVSRVSSWDQLPAAVARARRHDPKVIVEAAISGRELECGVLEMPDGTLEASTL
GEIRVAGVRGREDSFYDFATKYLDDAAELDVPAKVDDQVAEAIRQLAIRAFAAIDCRGLA
RVDFFLTDDGPVINEINTMPGFTTISMYPRMWAASGVDYPTLLATMIETALARGVGLH
NT seq
1077 nt
NT seq
+upstream
nt +downstream
nt
gtgttcggcgggcgcagcaacgagcacgccatctcgtgtgtgtccgccggcagcatcctg
cgcaacctggactcgcggcggttcgacgtgatcgcggtgggtatcaccccggcaggttcg
tgggtgctcaccgacgccaaccccgacgccctgacgatcaccaaccgggagcttcctcag
gtcaaatcaggatcgggcaccgagctggcgctgccggccgatccgcggcgtggtggccag
ttggtgtcgctgccgcccggggccggcgaggttctggagtcggtcgacgtggtgttcccg
gtactgcacggcccgtacggcgaggacggcacgatccagggactgctcgaactcgccggg
gtgccctacgtgggcgccggtgtgctggccagtgccgtcggcatggacaaggagttcacc
aagaagctgctcgccgccgatggacttccggtgggtgcgtacgcggtgctgcgtccgccg
cggtcgacactgcaccgccaggagtgcgaacggctgggcttaccggtgttcgtcaaaccc
gcccgaggcggctcgtcgatcggtgttagccgggtgtcgagttgggatcaactgcccgcc
gcggtcgcgcgggcccgccggcatgaccctaaggtcatcgtcgaggccgcgatcagcggc
cgcgagctggaatgcggtgtgctcgaaatgccggacggcacactggaagccagcacgctg
ggggagatccgggtggccggggtgcggggacgcgaggactctttctacgacttcgcaacc
aagtatctcgacgacgcagccgaattggacgtgcccgccaaggtcgatgaccaggtcgca
gaggcgattcgtcagctggcgatccgggcgttcgcggctatcgactgccggggtctggcc
agggtggacttcttcctcaccgacgacggtccggtgatcaacgagatcaacacgatgccg
ggattcaccacgatctcgatgtacccgcggatgtgggcggccagcggtgtcgactatccg
accctgctggcgacgatgatcgagacggcattggcccgcggcgtgggcctgcactag
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