Mycobacterium tuberculosis CDC1551: MT0777
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Entry
MT0777 CDS
T00053
Symbol
mmsA
Name
(GenBank) methylmalonic acid semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
mtc
Mycobacterium tuberculosis CDC1551
Pathway
mtc00280
Valine, leucine and isoleucine degradation
mtc00410
beta-Alanine metabolism
mtc00562
Inositol phosphate metabolism
mtc00640
Propanoate metabolism
mtc01100
Metabolic pathways
mtc01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
mtc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MT0777 (mmsA)
00562 Inositol phosphate metabolism
MT0777 (mmsA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MT0777 (mmsA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
MT0777 (mmsA)
Enzymes [BR:
mtc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
MT0777 (mmsA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
MT0777 (mmsA)
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Gene cluster
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
AAK45018
UniProt:
Q7D9C1
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Position
complement(846562..848094)
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AA seq
510 aa
AA seq
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MATQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA
WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL
KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP
SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA
TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR
ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL
TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE
YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA
IQFYTKVKTVTSRWPSGIKDGAEFVIPTMS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atggccacacagatttcacatttcatcgacggacaacgcaccgccggccagtccacgcgc
tcggccgacgtcttcgaccccaacaccggccagatccaggcgaaggtaccgatggccggc
aagtcagacatcgacgcggccgtggcctccgcggtcgaggcccaaaagggctgggccgca
tggaatccccagcgccgtgcccgggtgttgatgcggtttatcgaactggtcaacgacacc
atcgacgagttggccgagctgttgtcgcgtgagcacggcaaaacgctggccgacgcccgc
ggcgacgtccagcgcggcatcgaggtaatcgagttctgcctgggcattccccacctgctc
aagggcgagtacaccgagggtgccggccccggcatcgacgtctattcgctgcggcagccc
ctgggtgtggtcgcggggatcaccccgttcaacttcccggcgatgattccgctgtggaag
gccggcccggccctagcgtgcggcaacgccttcgtgctcaagccaagtgagcgcgacccg
tcggttccggtgaggctggccgagctgttcatcgaggcgggcctgccggcgggcgtgttc
caggtggtgcacggcgacaaggaggccgtcgacgccatcctgcaccaccccgacatcaag
gccgtcggcttcgtcggcagctcggatatcgctcagtacatctacgctggtgccgccgcc
accggcaagcgggcgcagtgtttcggcggtgccaagaaccacatgatcgtgatgcccgac
gcggacctggatcaggccgtggacgcactgatcggcgccggatacggcagcgccggcgaa
cgctgcatggcgatcagcgtcgccgtgccggtgggcgatcagaccgcggagcggttgcgc
gccaggctgatcgagcggatcaataacttgcgggtgggacacagcctggaccccaaggcg
gactacggcccgctggtcaccggggcggcgctggcgcgggtgcgcgactacatcggccag
ggtgtggccgccggtgccgagctggtcgttgacggccgcgaccgcgccagcgacgacctg
acctttgggctgcctgaaggcgatgcgaacctggagggcggcttcttcatcgggccgacc
ctgttcgaccatgtcgctgcccacatgtcgatctacaccgacgaaatcttcgggccggtg
ttgtgcatggttcgcgcccgcgactacgaagaggcgttgcggctgccgtcggagcacgaa
tacggcaacggggtggcgatcttcacccgcgacggcgacgcggcccgcgacttcgtctcc
cgggtgcaggtgggcatggtcggcgtcaacgtgccgatcccggtgccggtggcctaccac
actttcggcggctggaagcgctccggcttcggcgacctcaaccagcacggcccggcggca
atccagttctacaccaaggtcaagaccgtcacgtcgcgatggccgtcaggcatcaaggac
ggtgccgaattcgtcatccccacaatgagttag
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