Mycobacterium tuberculosis RGTB423: MRGA423_05890
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Entry
MRGA423_05890 CDS
T01994
Name
(GenBank) ATP-dependent DNA ligase
KO
K01971
bifunctional non-homologous end joining protein LigD [EC:
6.5.1.1
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti03450
Non-homologous end-joining
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09120 Genetic Information Processing
09124 Replication and repair
03450 Non-homologous end-joining
MRGA423_05890
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
mti03400
]
MRGA423_05890
Enzymes [BR:
mti01000
]
6. Ligases
6.5 Forming phosphoric-ester bonds
6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
6.5.1.1 DNA ligase (ATP)
MRGA423_05890
DNA repair and recombination proteins [BR:
mti03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
Two-component NHEJ DNA repair complex
MRGA423_05890
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
LigD_Prim-Pol
LigD_N
DNA_ligase_A_M
DNA_ligase_A_C
DNA_primase_S
RNA_ligase
Motif
Other DBs
NCBI-ProteinID:
AFE12226
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All DBs
Position
1046898..1049180
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AA seq
760 aa
AA seq
DB search
MGSASEQRVTLTNADKVLYPATGTTKSDIFDYYAGVAEVMLGHIAGRPATRKRWPNGVDQ
PAFFEKQLALSAPPWLSRATVAHRSGTTTYPIIDSATGLAWIAQQAALVGGRVPQWRFVA
EPGSGELNPGPATRLVFDLDPGEGVMMAQLAEVARAVRDLLADIGLVTFPVTSGSKGLHL
YTPLDEPVSSRGATVLAKRVAQRLEQAMPALVTSTMTKSLRAGKVFVDWSQNSGSKTTIA
PYSLRGRTHPTVAAPRTWAELDDPALRQLSYDEVLTRIARDGDLLERLDADAPVADRLTR
YRRMRDASKTPEPIPTAKPVTGDGNTFVIQEHHARRPHYDFRLERDGVLVSWAVPKNLPD
NTSVNHLAIHTEDHPLEYATFEGAIPSGEYGAGKVIIWDSGTYDTEKFHDDPHTGEVIVN
LHGGRISGRYALIRTNGDRWLAHRLKNQKDQKVFEFDNLAPMLATHGTVAGLKASQWAFE
GKWDGYRLLVEADHGAVRLRSRSGRDVTAEYPQLRALAEDLADHHVVLDGEAVVLDSSGV
PSFSQMQNRGRDTRVEFWAFDLLYLDGRALLGTRYQDRRKLLETLANATSLTVPELLPGD
GAQAFACSRKHGWEGVIAKRRDSRYQPGRRCASWVKDKHWNTQEVVIGGWRAGEGGHSSG
VGSLLMGIPGPGGLQFAGRVGTGLSERELANLKEMLAPLHTDESPFDVPLPARDAKGITY
VKPALVAEVRYSEWTPEGRLRQSSWRGLRPDKKPSEVVRE
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
atgggttcggcgtcggagcaacgggtgacgctgaccaacgccgacaaggtgctctatccc
gccaccgggaccacaaagtccgatatcttcgactactacgccggtgttgccgaagtcatg
ctcggccacatcgcgggacggccggcgacgcgcaagcgctggcctaacggcgtcgaccaa
cccgcgttcttcgaaaagcagttggcgttgtcggcgccgccttggctgtcacgtgcaacg
gtggcgcaccggtccgggacgacgacctatccgatcatcgatagcgcaaccgggctggcc
tggatcgcccaacaggcggcgctggtggggggccgagtgccgcagtggcggtttgtcgcc
gagcccggatcaggtgagttaaatccgggcccggcaacgcgtttggtgttcgacctggac
ccgggcgaaggcgtgatgatggcccagctggccgaggtggcgcgcgcggttcgtgatctt
ctcgccgatatcgggttggtcaccttcccggtcaccagcggcagcaagggattgcatctg
tacacaccgctggatgagccggtgagcagcaggggagccacggtgttggccaagcgcgtc
gcgcagcgattggagcaggcgatgcccgcgttggtcacctcgaccatgaccaaaagcctg
cgggccgggaaggtgtttgtggactggagccagaacagcggctcgaagaccaccatcgcg
ccgtactcactacgtggccggacgcatccgaccgtcgcggcgccacgcacctgggcggag
ctcgacgaccccgcactgcgtcagctctcctacgacgaggtgctgacccggattgcccgc
gacggcgatctgctcgagcggctggatgccgacgctccggtagcggaccggttgacccga
taccgccgcatgcgcgacgcatcgaaaactcccgagccgattcccacggcgaaacccgtt
accggagacggcaatacgttcgtcatccaggagcatcacgcgcgtcggccgcactacgat
ttccggctggaacgcgacggcgtgctggtctcgtgggcggtaccgaaaaacctgcccgac
aacacatcggttaaccatctagcgatacacaccgaggaccacccgctggaatacgccacg
ttcgagggcgcgattcccagcggggagtacggcgccggcaaggtgatcatctgggactcc
ggcacttacgacaccgagaagttccacgatgacccgcacacgggggaggtcatcgtgaat
ctgcacggcggccggatctctgggcgttatgcgctgattcggaccaacggcgatcggtgg
ctggcgcaccgcctaaagaatcagaaagaccagaaggtgttcgagttcgacaatctggcc
ccaatgcttgccacgcacggcacggtggccggtctaaaggccagccagtgggcgttcgaa
ggcaagtgggacggctaccggttgctggttgaggctgaccacggcgccgtgcggctgcgg
tcccgcagcgggcgcgatgtcaccgccgagtatccgcaattgcgggcattggcggaggat
ctcgccgatcaccacgtggtgctggacggcgaggccgtcgtacttgactcctctggtgtg
cccagcttcagccagatgcagaatcggggccgcgacacccgtgtcgagttctgggcgttc
gacctgctctacctcgacggccgcgcgctgctaggcacccgctaccaagaccggcgtaag
ctgctcgaaaccctagctaacgcaaccagtctcaccgttcccgagctgctgcccggtgac
ggcgcccaagcgtttgcgtgctcgcgcaagcacggctgggagggcgtgatcgccaagagg
cgtgactcgcgctatcagccgggccggcgctgcgcgtcgtgggtcaaggacaagcactgg
aacacccaggaagtcgtcattggtggctggcgcgccggggaaggcgggcacagcagtggc
gtcgggtcgctgctcatgggcatccccggtccaggtgggctgcagttcgccgggcgggtc
ggtaccggcctcagcgaacgcgaactggccaacctcaaggagatgctggcgccgctgcat
accgacgagtcccccttcgacgtaccactgcccgcgcgtgacgccaagggcatcacatat
gtcaagccggcgctggttgcagaggtgcgctacagcgagtggactccggagggccggctg
cgtcaatcaagctggcgtgggctgcggccggacaagaaacccagtgaggtggtgcgcgaa
tga
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