Mycobacterium tuberculosis EAI5: M943_03935
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Entry
M943_03935 CDS
T02749
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
mtx
Mycobacterium tuberculosis EAI5
Pathway
mtx00280
Valine, leucine and isoleucine degradation
mtx00410
beta-Alanine metabolism
mtx00562
Inositol phosphate metabolism
mtx00640
Propanoate metabolism
mtx01100
Metabolic pathways
mtx01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
mtx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
M943_03935
00562 Inositol phosphate metabolism
M943_03935
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
M943_03935
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
M943_03935
Enzymes [BR:
mtx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
M943_03935
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
M943_03935
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
AGQ34264
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Position
complement(844433..845965)
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AA seq
510 aa
AA seq
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MTTQISHFIDGQRTAGQSTRSADVFDPNTGQIQAKVPMAGKSDIDAAVASAVEAQKGWAA
WNPQRRARVLMRFIELVNDTIDELAELLSREHGKTLADARGDVQRGIEVIEFCLGIPHLL
KGEYTEGAGPGIDVYSLRQPLGVVAGITPFNFPAMIPLWKAGPALACGNAFVLKPSERDP
SVPVRLAELFIEAGLPAGVFQVVHGDKEAVDAILHHPDIKAVGFVGSSDIAQYIYAGAAA
TGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGDQTAERLR
ARLIERINNLRVGHSLDPKADYGPLVTGAALARVRDYIGQGVAAGAELVVDGRDRASDDL
TFGLPEGDANLEGGFFIGPTLFDHVAAHMSIYTDEIFGPVLCMVRARDYEEALRLPSEHE
YGNGVAIFTRDGDAARDFVSRVQVGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPAA
IQFYTKVKTVTSRWPSGIKDGAEFVIPTMS
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgaccacacagatttcacatttcatcgacggacaacgcaccgccggccagtccacgcgc
tcggccgacgtcttcgaccccaacaccggccagatccaggcgaaggtaccgatggccggc
aagtcagacatcgacgcggccgtggcctccgcggtcgaggcccaaaagggctgggccgca
tggaatccccagcgccgtgcccgggtgttgatgcggtttatcgaactggtcaacgacacc
atcgacgagttggccgagctgttgtcgcgtgagcacggcaaaacgctggccgacgcccgc
ggcgacgtccagcgcggcatcgaggtaatcgagttctgcctgggcattccccacctgctc
aagggcgagtacaccgagggtgccggccccggcatcgacgtctattcgctgcggcagccc
ctgggtgtggtcgcggggatcaccccgttcaacttcccggcgatgattccgctgtggaag
gccggcccggccctagcgtgcggcaacgccttcgtgctcaagccaagtgagcgcgacccg
tcggttccggtgaggctggccgagctgttcatcgaggcgggcctgccggcgggcgtgttc
caggtggtgcacggcgacaaggaggccgtcgacgccatcctgcaccaccccgacatcaag
gccgtcggcttcgtcggcagctcggatatcgctcagtacatctacgctggtgccgccgcc
accggcaagcgggcgcagtgtttcggcggtgccaagaaccacatgatcgtgatgcccgac
gcggacctggatcaggccgtggacgcactgatcggcgccggatacggcagcgccggcgaa
cgctgcatggcgatcagcgtcgccgtgccggtgggcgatcagaccgcggagcggttgcgc
gccaggctgatcgagcggatcaataacttgcgggtgggacacagcctggaccccaaggcg
gactacggcccgctggtcaccggggcggcgctggcgcgggtgcgcgactacatcggccag
ggtgtggccgccggtgccgagctggtcgttgacggccgcgaccgcgccagcgacgacctg
acctttgggctgcctgaaggcgatgcgaacctggagggcggcttcttcatcgggccgacc
ctgttcgaccatgtcgctgcccacatgtcgatctacaccgacgaaatcttcgggccggtg
ttgtgcatggttcgcgcccgcgactacgaagaggcgttgcggctgccgtcggagcacgaa
tacggcaacggggtggcgatcttcacccgcgacggcgacgcggcccgcgacttcgtctcc
cgggtgcaggtgggcatggtcggcgtcaacgtgccgatcccggtgccggtggcctaccac
actttcggcggctggaagcgctccggcttcggcgacctcaaccagcacggcccggcggca
atccagttctacaccaaggtcaagaccgtcacgtcgcgatggccgtcaggcatcaaggac
ggtgccgaattcgtcatccccacaatgagttag
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